Isle of Palms, SC Vacation Homes from ￥48,234

A pier extending into calm waters at sunset with a pink and blue sky.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Isle of Palms vacation homes

A kitchen with a marble countertop, a wine bottle, two glasses of red wine, a cheese board with various cheeses and grapes, and a window with a view of greenery.

1. Steps from the beach, extraordinary luxurious home and perfect outdoor space

Isle of Palms

Courtney B.

￥137,343 total

includes taxes & fees

Nov 2 - Nov 3

A multi-story house with a spacious patio area, a covered deck, and a driveway.

2. King's Isle Ocean View, LSV, Pool, Ebikes, Rooftop

Isle of Palms

"The house was beautifully designed, built with high-end materials, and finished with exceptional attention to detail. It was also very well equipped, with plenty of towels, beach chairs, and even paper goods.The host was readily available to answer any questions or address any concerns and responded incredibly quickly every time.I highly recommend this property to anyone staying on Isle of Palms (IOP)."

christian b.

A covered outdoor seating area with a checkered floor, a table, and a chair.

3. Oceanfront Villa w/ Wild Dunes Passes, Golfcart, Private Gym & Sauna & 8 beds!

Isle of Palms

A two-story house with a swimming pool, outdoor seating, and a staircase connecting the levels.

4. The Ivory Tide by Charleston Vacays

Isle of Palms

￥348,872 total

includes taxes & fees

Nov 10 - Nov 11

A room with a white wooden interior, a ceiling fan, a table with wicker chairs, and large windows.

5. Ocean Boulevard | 7BR IOP Beach House | Sleeps 14

Ocean Boulevard

Bridget A.

￥305,237 total

includes taxes & fees

Oct 28 - Oct 29

A modern kitchen with blue cabinets, a large island with stools, and a refrigerator.

6. Modern House in Old Village. Walk to Dining & Coffee. Bikes, Ping Pong, Fire Pit

Old Village

Richard F R.

￥52,348 total

includes taxes & fees

Nov 24 - Nov 25

A dining area with a round table and chairs, a kitchen in the background, and a black door with windows.

7. Southern Comfort | Minutes to CHS | Grill!

Harborgate Shores

Carol K.

￥72,164 total

includes taxes & fees

Oct 29 - Oct 30

A dining area with a glass table, wooden chairs, and a central decorative bowl.

8. Fenced In Backyard! | The Fox Pond

Old Village

Brianne H.

￥64,852 total

includes taxes & fees

Oct 28 - Oct 29

View all properties

Find vacation rentals that suit your style

Private vacation homes

Aparthotels

Save an average of 15% on thousands of hotels when you're signed in

Top Isle of Palms Hotel Reviews

Seaside Inn Oceanfront

10/10 Excellent

"Everyone at the Seaside Inn was so nice and helpful to us. We came from Vermont and met friends who came from Florida. Our friends needed to change rooms the first night through no reason of the Inn, but a problem our friends had. They accommodated them so generously. Then when we could find no place in town to charge the golf cart we rented and had such a great time riding around in, the inn helped us get that charged too! Then there were the 2 pancake machines. I really looked forward to those delicious pancakes!! Also, boiled eggs, grits, oatmeal, bagels, cereal, bananas, apples, oranges, 3 bottled juices that you could take with you, yogurt. There was always bottled water, coffee, and tea available. The ocean was right out front down a short path. The room was spacious and clean. The only problem we had was a lack of a chair in the room. There was one high level, stiff chair in front of a desk, but no real comfortable chair to sit in and plenty of room for even 2 of them! Also worth a mention was the Acme Low Country Cafe restaurant. We ate there four times including breakfast, lunch and dinner and every meal was so tasty and the service was outstanding. It was so close the inn, maybe a 5 minute walk."

Oceanfront Condo with Community Pool, Beach Access, Ocean & Beach Views and Private Covered Balcony

8/10 Good

"We were impressed with how secure and private Wild Dunes was in driving to Seascapes. Upon arriving in the condo…we were blown away by the amazing view and the quiet of the location. The only thing that we could possibly find that could be considered a negative experience was the lack of comfort in the furniture. It’s very difficult to relax in the condo…but the bed and the rest of the facility was excellent!!!!"

Charleston has The Best of all Worlds-Beachfront, 2nd floor A+ Views & Location!

10/10 Excellent

"Susan is AMAZING host! The listing is exactly how she describes. There isn’t updated appliances or granite counters, but a cozy little beach condo in a perfect location. I couldn’t have asked for better communication. Susan was by far an amazing host. She did a check in mid week to ensure we had settled in and enjoying our time."

Find out more about Isle of Palms

Isle of Palms Vacation Homes information

Number of reviews	918
Accommodation	1018 Vacation Homes
Lowest Price	￥48,234
Highest Price	￥348,872

Explore a world of travel with Expedia

More ways to book

Book Vacation Homes in Isle of Palms on Expedia.com

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Isle of Palms vacation homes

1. Steps from the beach, extraordinary luxurious home and perfect outdoor space

2. King's Isle Ocean View, LSV, Pool, Ebikes, Rooftop