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Our top choices for South Central Houston hotels

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (159 reviews)
"Great place. The staff is very friendly and the place is clean."
United States
Fernando
The price is ¥13,825
¥16,176 total
includes taxes & fees
Jun 8 - Jun 9
Downtowner Inns - Houston Downtown

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1,949 reviews)
"Great stay and clean room"
United States
Ethel
The price is ¥14,241
¥16,849 total
includes taxes & fees
Jun 6 - Jun 7
Hilton Houston Plaza/Medical Center

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,157 reviews)
"Clean room,restaurant exceptional,excellent staff."
United States
Craig
The price is ¥30,221
¥37,615 total
includes taxes & fees
Jun 6 - Jun 7
The Westin Houston Medical Center/Museum District

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (2 reviews)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is ¥10,051
¥12,765 total
includes taxes & fees
Jun 10 - Jun 11
Golden Motel Near Houston Medical Center

Houston Hideaway Near Downtown Attractions

Houston Hideaway Near Downtown Attractions
2.0 star property
South Central Houston
The price is ¥9,333
¥79,508 total
includes taxes & fees
Jun 8 - Jun 9
Houston Hideaway Near Downtown Attractions

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
8.8 out of 10, Excellent, (48 reviews)
"Very chic, very interesting room. Love this place"
United States
Chase
The price is ¥30,242
¥40,063 total
includes taxes & fees
Jun 8 - Jun 9
Sentral Forme Houston

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1,007 reviews)
"Convenient location and comfortable room."
United States
Rogelio
The price is ¥13,281
¥15,539 total
includes taxes & fees
Jun 7 - Jun 8
Americas Best Value Inn Medical Center Downtown

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,012 reviews)
"Overall great hotel. Definitely will be staying here again. Shout out to the staff crew."
United States
Vincent
The price is ¥32,237
¥44,965 total
includes taxes & fees
Jun 6 - Jun 7
Hotel Zaza Houston Museum District

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,007 reviews)
"Great stay, nice staff"
United States
Allen David
The price is ¥25,454
¥32,981 total
includes taxes & fees
Jun 7 - Jun 8
InterContinental Houston by IHG

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
"Nice and helpful staff, clean rooms, nice amenities "
United States
Andrea
The price is ¥30,242
¥40,614 total
includes taxes & fees
Jun 6 - Jun 7
Houston Marriott Medical Center/Museum District

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,016 reviews)
"Perfect place for my family and I to stay when one of us has an appointment at MD Anderson. Super affordable and extremely close to the appointment locations. Stayed there 4 times with out any issues."
United States
Catherine
The price is ¥13,526
¥15,873 total
includes taxes & fees
Jun 7 - Jun 8
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (950 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is ¥23,270
¥27,226 total
includes taxes & fees
Jun 12 - Jun 13
Hilton University of Houston

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (597 reviews)
"was ok"
United States
Guillermo
The price is ¥23,825
¥27,875 total
includes taxes & fees
Jun 7 - Jun 8
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Cozy 2BR Near NRG & Downtown FIFA World Cup

Cozy 2BR Near NRG & Downtown FIFA World Cup
3.0 star property
South Central Houston
The price is ¥17,172
¥46,872 total
includes taxes & fees
Jun 8 - Jun 9
Cozy 2BR Near NRG & Downtown FIFA World Cup

2-bedroom - Equipped Kitchen - Gated Parking

2-bedroom - Equipped Kitchen - Gated Parking
2.0 star property
South Central Houston
The price is ¥11,760
¥97,140 total
includes taxes & fees
Jun 9 - Jun 10
2-bedroom - Equipped Kitchen - Gated Parking

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (213 reviews)
"Neat place. They had snacks available and also helped with our bags."
United States
David
The price is ¥33,099
¥41,125 total
includes taxes & fees
Jun 8 - Jun 9
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (575 reviews)
"We felt welcome from the moment we walked in. The owners are so hospitable and the place such a delight. Loved the generous breakfast and ambiance- great parking as well!"
United States
Carolina
The price is ¥27,783
¥32,506 total
includes taxes & fees
Jul 6 - Jul 7
La Maison in Midtown an urban B&B

Luxury Med Center Fully Equipped King Sized Bed Condos

Luxury Med Center Fully Equipped King Sized Bed Condos
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (92 reviews)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
United States
Gordon
The price is ¥22,345
¥41,345 total
includes taxes & fees
Jun 30 - Jul 1
Luxury Med Center Fully Equipped King Sized Bed Condos

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (238 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is ¥16,478
¥19,278 total
includes taxes & fees
Jun 8 - Jun 9
Southmore Boulevard Motel

MorningSide Inn

MorningSide Inn
2.0 star property
South Central Houston
6.0 out of 10, (514 reviews)
"There is no coffeemaker anywhere no schuttel. This place should be razed ."
United States
Barbara
The price is ¥11,201
¥13,106 total
includes taxes & fees
Jun 6 - Jun 7
MorningSide Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in South Central Houston

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
575 reviews
View
Laptop workspace, blackout drapes, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
159 reviews
View
Premium bedding, pillowtop beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,012 reviews
View
Outdoor pool, free cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,157 reviews
View
Exterior
InterContinental Houston by IHG
4.0 star property
9.2
Wonderful
1,007 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Rothko Chapel while you're exploring the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.
What's the best accommodation in South Central Houston?
Based on our traveler data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and Sentral Forme Houston.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1197 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Houston Zoo and Fertitta Center are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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