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Check prices for these dates

Next weekend
Jun 12 - Jun 14
In two weeks
Jun 19 - Jun 21

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Airport transfer and breakfast were great!"
United States
Halima
The price is ￥15,260
￥17,187 total
Jun 14 - Jun 15
Wyndham Guayaquil Puerto Santa Ana
Rooftop terrace

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (53 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ￥12,454
￥12,614 total
Jun 9 - Jun 10
River View suites Puerto Santa Ana gye
Living area

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
The price is ￥7,545
￥7,705 total
Jun 15 - Jun 16
NP Hotel & Suites
Outdoor pool, sun loungers

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is ￥16,770
￥18,733 total
Jun 15 - Jun 16
Iguanazu Bed & Breakfast
Terrace/patio

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (115 reviews)
"Breakfast excellent"
United States
Priscilla
The price is ￥46,035
￥50,639 total
Jun 11 - Jun 12
Hotel del Parque
Cafe

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,007 reviews)
"Great place"
Canada
Michael
The price is ￥16,029
￥18,033 total
Jun 21 - Jun 22
Holiday Inn Guayaquil Airport by IHG
Lobby

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (98 reviews)
"Great and safe hotel Always security"
United States
Aaron
The price is ￥10,130
￥11,945 total
Jun 19 - Jun 20
Doubletree By Hilton Guayaquil
Family House, Private Pool | Living area | Flat-screen TV

Casa con Piscina Privada para Familias

Casa con Piscina Privada para Familias
3.0 star property
15.7 km from Puerto Santa Ana
2.0 out of 10, (2 reviews)
"More cleaning, there was rotten garbage and a bad smell emanated"
United States
Isabel
The price is ￥18,638
￥21,844 total
Jun 10 - Jun 11
Casa con Piscina Privada para Familias
Lobby

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.6 out of 10, Excellent, (920 reviews)
"Excellent stay highly recommended"
United States
Carol
The price is ￥15,773
￥17,751 total
Jun 14 - Jun 15
Hilton Colon Guayaquil
Exterior

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ￥7,694
￥7,694 total
Jun 8 - Jun 9
Hotel La Ria Durán
Daily buffet breakfast for a fee

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (653 reviews)
"The food was delicious the staff was very friendly I recommend this hotel "
Canada
Monica
The price is ￥17,632
￥20,678 total
Jun 12 - Jun 13
Sheraton Guayaquil Hotel
Children's activities

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,010 reviews)
"Great place to stay"
United States
Daniel
The price is ￥13,625
￥15,388 total
Jun 12 - Jun 13
Oro Verde Guayaquil
Double Room, 1 Queen Bed, Private Bathroom, Ground Floor | Outdoor pool | Outdoor pool, sun loungers

MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
8.4 out of 10, Very Good, (172 reviews)
"We stay here anytime that we have a late arrival or early flight from Ecuador. They are always helpful when we are looking for something. There is a traditional Ecuadorian family type restaurant 100 feet from the hotel and several rental car agencies a couple of hundred meters from there. And naturally my daughter loves the pool. "
United States
Christopher
The price is ￥7,492
￥7,652 total
Jun 8 - Jun 9
MundialCity Hotel Guayaquil
Exterior detail

NCG Suite 5

NCG Suite 5
2.5 star property
7.1 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"loved everything "
United States
Betty
The price is ￥5,610
￥5,610 total
Jun 12 - Jun 13
NCG Suite 5
Front of property

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 3.5 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (181 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is ￥15,436
￥15,596 total
Jun 8 - Jun 9
Luxva Hotel Boutique
Lobby lounge

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (139 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ￥9,521
￥10,633 total
Jun 9 - Jun 10
Mansión del Río
Free minibar, in-room safe, soundproofing, iron/ironing board

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ￥67,322
￥74,735 total
Jun 10 - Jun 11
Hotel Río Guayas by Art Hotels Ecuador
Property grounds

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (10 reviews)
"Very convenient to airport and local shopping. Outstanding service and price."
United States
Scottie
The price is ￥11,198
￥11,358 total
Jun 8 - Jun 9
Hostal Macaw
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Nice place, close to everything"
United States
Amira
The price is ￥12,823
￥14,345 total
Jun 12 - Jun 13
Wyndham Garden Guayaquil
Property entrance

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (694 reviews)
"Good hotel"
United States
juan pablo
The price is ￥14,266
￥16,094 total
Jun 14 - Jun 15
Radisson Hotel Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and La Rotonda while you're in town.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Sports Federation of Guayas are some notable places to visit nearby.

Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Puerto Santa Ana Hotel Reviews

Oro Verde Guayaquil

Oro Verde Guayaquil

10/10 Excellent
"Everybody were so nice and helpful. Food was delicious. very clean and safe"
Karina 7-night trip
Posted 11 hours ago
Oro Verde Guayaquil

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 80 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.