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Check prices for these dates

This weekend
Jun 5 - Jun 7
Next weekend
Jun 12 - Jun 14

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,005 reviews)
"great safe place will be back "
United States
Tracy
The price is ￥17,137
￥19,251 total
Jun 14 - Jun 15
Wyndham Guayaquil Puerto Santa Ana
Rooftop terrace

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (53 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ￥12,808
￥12,968 total
Jun 9 - Jun 10
River View suites Puerto Santa Ana gye
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
Luxury Suites Riverfront GYE
Outdoor pool, sun loungers

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
5.4 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is ￥17,449
￥19,408 total
Jun 26 - Jun 27
Iguanazu Bed & Breakfast
Living area

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
9.7 km from Puerto Santa Ana
The price is ￥7,527
￥7,687 total
Jun 21 - Jun 22
NP Hotel & Suites
Terrace/patio

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (115 reviews)
"Breakfast excellent"
United States
Priscilla
The price is ￥45,955
￥50,550 total
Jun 11 - Jun 12
Hotel del Parque
Exterior

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ￥7,675
￥7,675 total
Jun 9 - Jun 10
Hotel La Ria Durán
Cafe

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,007 reviews)
"Great place"
Canada
Michael
The price is ￥15,681
￥17,649 total
Jun 13 - Jun 14
Holiday Inn Guayaquil Airport by IHG
Children's activities

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,007 reviews)
"Great place to stay"
United States
Daniel
The price is ￥13,601
￥15,361 total
Jun 6 - Jun 7
Oro Verde Guayaquil
Daily buffet breakfast for a fee

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (653 reviews)
"The food was delicious the staff was very friendly I recommend this hotel "
Canada
Monica
The price is ￥17,601
￥20,641 total
Jun 6 - Jun 7
Sheraton Guayaquil Hotel
Lobby

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 3.2 km from Puerto Santa Ana
8.6 out of 10, Excellent, (920 reviews)
"Excellent stay highly recommended"
United States
Carol
The price is ￥17,371
￥19,508 total
Jun 28 - Jun 29
Hilton Colon Guayaquil
Exterior detail

NCG Suite 5

NCG Suite 5
2.5 star property
7.1 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"loved everything "
United States
Betty
The price is ￥5,597
￥5,597 total
Jun 14 - Jun 15
NCG Suite 5
Front of property

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 3.5 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (181 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is ￥15,409
￥15,569 total
Jun 6 - Jun 7
Luxva Hotel Boutique
Property grounds

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (10 reviews)
"Very convenient to airport and local shopping. Outstanding service and price."
United States
Scottie
The price is ￥11,171
￥11,331 total
Jun 9 - Jun 10
Hostal Macaw
Lobby lounge

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (139 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ￥9,498
￥10,608 total
Jun 14 - Jun 15
Mansión del Río
Lobby

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (97 reviews)
"The river view is spectacular"
United States
silvia
The price is ￥10,113
￥11,924 total
Jun 21 - Jun 22
Doubletree By Hilton Guayaquil
Terrace/patio

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 3.7 km from Puerto Santa Ana
8.6 out of 10, Excellent, (262 reviews)
"Very close to the airport. Our triple room was very spacious, clean, and modern. When our taxi did not show up, the security guard drove us to the airport."
Canada
Glenn
The price is ￥8,871
￥9,111 total
Jun 13 - Jun 14
Hotel Puerto Pacifico Guayaquil Airport
Lobby

Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,005 reviews)
"Great location!"
United States
Laura
The price is ￥12,001
￥13,441 total
Jun 12 - Jun 13
Courtyard by Marriott Guayaquil
Double Room, 1 Queen Bed, Private Bathroom, Ground Floor | Outdoor pool | Outdoor pool, sun loungers

MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 3 km from Puerto Santa Ana
8.4 out of 10, Very Good, (172 reviews)
"We stay here anytime that we have a late arrival or early flight from Ecuador. They are always helpful when we are looking for something. There is a traditional Ecuadorian family type restaurant 100 feet from the hotel and several rental car agencies a couple of hundred meters from there. And naturally my daughter loves the pool. "
United States
Christopher
The price is ￥7,475
￥7,635 total
Jun 17 - Jun 18
MundialCity Hotel Guayaquil
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice place, close to everything"
United States
Amira
The price is ￥14,401
￥16,081 total
Jun 6 - Jun 7
Wyndham Garden Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and La Rotonda while you're in town.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Sports Federation of Guayas are some notable places to visit nearby.

Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Puerto Santa Ana Hotel Reviews

Oro Verde Guayaquil

Oro Verde Guayaquil

10/10 Excellent
"All good. Great food and service. I’ll be back soon."
Christian 5-night trip
Posted 10 hours ago
Oro Verde Guayaquil

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 80 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.