Find hotels near Duke Regional Hospital, Raleigh from ￥10,601

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Duke Regional Hospital hotels

Free daily buffet breakfast
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.5 star property
2.2 km from Duke Regional Hospital
9.0 out of 10, Wonderful, (1003)
"Clean rooms and courteous staff."
United States
Katina
The price is ￥16,597
￥18,838 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hampton Inn & Suites Durham/North I-85
Free buffet breakfast
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.5 star property
2.4 km from Duke Regional Hospital
8.8 out of 10, Excellent, (957)
"Room was great"
United States
Barbara
The price is ￥15,219
￥17,274 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Express Durham by IHG
Lobby
Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.0 star property
2.3 km from Duke Regional Hospital
6.8 out of 10, (1003)
"Good motel...clean, easy acess "
United States
Howard
The price is ￥9,106
￥10,601 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Red Roof Inn Durham - Duke Univ Medical Center
Terrace/patio
Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
2.5 star property
5 km from Duke Regional Hospital
9.6 out of 10, Exceptional, (399)
"Great breakfast, clean rooms and beds "
United States
Fabiola B
The price is ￥17,885
￥20,299 total
includes taxes & fees
Dec 29 - Dec 30
Hampton Inn & Suites Durham University Medical Center
Carolina Log Cabin | Terrace/patio
Arrowhead Inn

Arrowhead Inn

Arrowhead Inn
4.5 star property
8.9 km from Duke Regional Hospital
9.8 out of 10, Exceptional, (119)
"Bed was very comfortable, breakfast was yummy, and the surroundings were beautiful"
United States
Ronald
The price is ￥30,784
￥34,939 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Arrowhead Inn
Exterior
JB Duke Hotel

JB Duke Hotel

JB Duke Hotel
4.0 star property
6.2 km from Duke Regional Hospital
9.4 out of 10, Exceptional, (542)
"Excellent on all levels! Will definitely stay here again!"
United States
Cherie Nan
The price is ￥23,378
￥26,535 total
includes taxes & fees
Dec 24 - Dec 25
JB Duke Hotel
Front of property
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
4.0 star property
6.6 km from Duke Regional Hospital
9.4 out of 10, Exceptional, (1002)
"Everything fabulous!"
United States
Terri
The price is ￥24,853
￥28,209 total
includes taxes & fees
Dec 25 - Dec 26
Washington Duke Inn & Golf Club
Reception
Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
3.0 star property
9th Street District, 4.1 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (1001)
"Just right for an overnight business trip "
United States
Cody
The price is ￥15,102
￥17,139 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn Durham/University Medical Center
Lobby
AC Hotel Durham

AC Hotel Durham

AC Hotel Durham
3.0 star property
5.4 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (617)
"Room was very clean, staff very helpful and nice. "
United States
Tia
The price is ￥18,538
￥21,041 total
includes taxes & fees
Dec 26 - Dec 27
AC Hotel Durham
Exterior
SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
3.5 star property
5.4 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (455)
"Yess the room was spotless and clean the check in was smooth "
United States
Vonisha
The price is ￥16,161
￥18,343 total
includes taxes & fees
Dec 28 - Dec 29
SpringHill Suites by Marriott Durham City View
Outdoor dining
The Durham Hotel

The Durham Hotel

The Durham Hotel
4.0 star property
Downtown Durham, 4.5 km from Duke Regional Hospital
9.0 out of 10, Wonderful, (641)
"Great stay. Very nice boutique hotel. "
United States
nadav
The price is ￥29,185
￥33,125 total
includes taxes & fees
Dec 26 - Dec 27
The Durham Hotel
Front of property
Aloft Durham Downtown

Aloft Durham Downtown

Aloft Durham Downtown
3.0 star property
American Tobacco District, 4.9 km from Duke Regional Hospital
9.0 out of 10, Wonderful, (731)
"Very friendly staff, very clean and convenient location"
United States
Robert
The price is ￥29,183
￥33,123 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Aloft Durham Downtown
Property grounds
Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
4.0 star property
17 km from Duke Regional Hospital
9.6 out of 10, Exceptional, (1001)
"Friendly staff, beautiful grounds to explore and excellent accommodations."
United States
Jason
The price is ￥22,138
￥25,126 total
includes taxes & fees
Dec 26 - Dec 27
Rizzo Center, a Destination by Hyatt Hotel
Hallway
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center
2.0 star property
4.5 km from Duke Regional Hospital
8.8 out of 10, Excellent, (1001)
"Great place"
United States
Chase
The price is ￥16,804
￥19,074 total
includes taxes & fees
Dec 24 - Dec 25
University Inn Durham next to Duke University Medical Center
Restaurant
The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
4.0 star property
18.6 km from Duke Regional Hospital
9.6 out of 10, Exceptional, (265)
"The room was great. Very clean. The staff was absolutely amazing! 10 out of 10! "
United States
Stuart
The price is ￥21,072
￥23,917 total
includes taxes & fees
Jan 12 - Jan 13, 2026
The Colonial Inn, an Ascend Collection Hotel
Premium bedding, desk, blackout drapes, iron/ironing board
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University
2.5 star property
Croasdaile Farm Master, 3.3 km from Duke Regional Hospital
8.6 out of 10, Excellent, (1005)
"Friendly staff, clean room, nice breakfast"
United States
Jessica
The price is ￥14,670
￥16,651 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn & Suites Durham near Duke University
Outdoor pool, sun loungers
Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
3.0 star property
16.1 km from Duke Regional Hospital
9.4 out of 10, Exceptional, (1003)
"The staff was awesome! The place very clean."
United States
Amy
The price is ￥19,142
￥21,726 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Place Durham Southpoint
Lobby
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
2.5 star property
18.2 km from Duke Regional Hospital
9.4 out of 10, Exceptional, (1000)
"Wonderful hotel "
United States
Robert
The price is ￥17,240
￥19,524 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Seasonal outdoor pool
The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport
4.0 star property
18.1 km from Duke Regional Hospital
9.4 out of 10, Exceptional, (280)
"Besides the last day of no electricity for the most part good stay"
United States
Chandra
The price is ￥32,321
￥36,604 total
includes taxes & fees
Jan 2 - Jan 3, 2026
The Westin Raleigh-Durham Airport
Property amenity
SpringHill Suites by Marriott Durham Chapel Hill

SpringHill Suites by Marriott Durham Chapel Hill

SpringHill Suites by Marriott Durham Chapel Hill
3.0 star property
12.7 km from Duke Regional Hospital
9.2 out of 10, Wonderful, (1006)
"I would stay there again if I was in the area! "
United States
Deborah
The price is ￥17,102
￥19,410 total
includes taxes & fees
Jan 4 - Jan 5, 2026
SpringHill Suites by Marriott Durham Chapel Hill
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Duke Regional Hospital Hotel Reviews

Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

10/10 Excellent
"Friendly staff, clean room, nice breakfast"
Jessica 1-night trip
Posted 2 days ago
Comfort Inn & Suites Durham near Duke University

Hotels near other Duke Regional Hospital attractions

Sennett's hole is a swimming hole accessed from the west point outpost on the eno river. There are lots of rocks to lounge on on one side, and a rope swing on the other. It's great spot to hang out!
Photo by Nikki Benson
Open Photo by Nikki Benson

West Point on the Eno

Explore the great outdoors at West Point on the Eno, a lovely green space in Durham. Attend a sporting event or visit the stunning cathedral in this family-friendly area.
See properties
Brightleaf is part of downtown Durham, NC's renaissance. Old tobacco warehouses have found new life as shops and restaurants.
Photo by Jeff Bechtel
Open Photo by Jeff Bechtel

Brightleaf Square

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Duke Regional Hospital?
Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 11 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Duke Regional Hospital?
Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 1.3 mi (2.2 km) from Duke Regional Hospital. Other good choices within a few miles include Comfort Inn & Suites Durham near Duke University and Holiday Inn Express Durham by IHG.
How many hotels can I expect to find near Duke Regional Hospital?
Expedia has 11 hotels and other accommodations within a mile from Duke Regional Hospital.
If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.
Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?
To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.
What can I see and do near Duke Regional Hospital?
You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can watch performances at Carolina Theatre, Durham Performing Arts Center, and Manbites Dog Theater if you're interested in local theater.