
Vacation Rentals in St. Lucie County
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Our top choices for St. Lucie County vacation rentals

9.4 out of 10, Exceptional, (98 reviews)

Sheraton PGA Vacation Resort, Port St. Lucie
Sheraton PGA Vacation Resort, Port St. LuciePort Saint Lucie
9.0 out of 10, Wonderful, (656 reviews)

Mins to Beaches & HCA Hospital: Fort Pierce Home
Mins to Beaches & HCA Hospital: Fort Pierce HomeLakewood Park

Casita Luna - Sunny boho retreat with a pool
Casita Luna - Sunny boho retreat with a poolFort Pierce
9.8 out of 10, Exceptional, (8 reviews)

Luxurious Pool Cottage Sleep 2
Luxurious Pool Cottage Sleep 2Port St. Lucie
9.4 out of 10, Exceptional, (25 reviews)

Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!Port St. Lucie
9.8 out of 10, Exceptional, (7 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find vacation rentals that suit your style
Aparthotels
Private vacation homes
Save an average of 15% on thousands of hotels when you're signed in
Top St. Lucie County Hotel Reviews

At Home Inn
2/10 Terrible
Find out more about St. Lucie County
Vacation Apartments in St. Lucie County
Search for Vacation rentals in St. Lucie County on Expedia! You can easily find your home rentals, villas, Vacation apartments in St. Lucie County using one of the methods below:
- View our selection of featured Vacation rentals in St. Lucie County
- Use the map to find apartments and other Vacation homes in the St. Lucie County neighbourhood you prefer
- Enter your travel dates to view the best deals on Vacation rentals in St. Lucie County while they last
Look no further and take a look at our great range of rental properties in St. Lucie County!

















































































