A calm river surrounded by dense trees reflecting the greenery.

Vacation Rentals in Pike County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for Pike County vacation rentals

Interior

1. Papa's Cabin - 40 acres & 5 acre lake!

Papa's Cabin - 40 acres & 5 acre lake!
Middletown
10.0 out of 10, Exceptional, (3 reviews)
"Overall stay was amazing! The property was just like described and the hostess was easy to communicate with."
United States
Prisilla B.
The price is ￥18,355
￥32,825 total
includes taxes & fees
Aug 23 - Aug 24
Papa's Cabin - 40 acres & 5 acre lake!
Interior

2. The Yellow Rose Historic Home

The Yellow Rose Historic Home
Louisiana
9.8 out of 10, Exceptional, (19 reviews)
"Everything was great!"
United States
Brendan R.
The price is ￥39,162
￥58,366 total
includes taxes & fees
Aug 23 - Aug 24
The Yellow Rose Historic Home
Room

3. Charming 3-bedroom house, 2-car garage, and pickleball court

Charming 3-bedroom house, 2-car garage, and pickleball court
Hannibal
10.0 out of 10, Exceptional, (2 reviews)
"The space was great for my family. It was clean, comfortable and Shelby was a great host. We will surely be back!"
United States
Jeanne M.
The price is ￥15,507
￥31,172 total
includes taxes & fees
Aug 23 - Aug 24
Charming 3-bedroom house, 2-car garage, and pickleball court
Room

4. Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.2 out of 10, Wonderful, (21 reviews)
"Cozy and well equipped with everything we may have needed"
United States
Olivia
The price is ￥16,250
￥17,286 total
includes taxes & fees
Aug 23 - Aug 24
Cannon Dam Cabins
Children's area

5. Deluxe two queen bed motel room packed with amenities.

Deluxe two queen bed motel room packed with amenities.
Perry
10.0 out of 10, Exceptional, (1 review)
"Older, but very clean and nice. "
United States
Anonymous traveler
The price is ￥15,000
￥19,120 total
includes taxes & fees
Aug 26 - Aug 27
Deluxe two queen bed motel room packed with amenities.
Interior

6. Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
Hannibal
10.0 out of 10, Exceptional, (6 reviews)
"Pretty place. Awesome location. Had such a good time"
United States
janette b.
The price is ￥15,665
￥47,775 total
includes taxes & fees
Aug 23 - Aug 24
Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
Room

7. The Farmhouse Loft "Greene County's Guesthouse"

The Farmhouse Loft "Greene County's Guesthouse"
Carrollton
9.8 out of 10, Exceptional, (62 reviews)
"Stayed at the Farmhouse Loft for a local wedding. It met all our expectations. Great location on the town square. Will definitely stay there again "
United States
Gregory D.
The price is ￥13,450
￥25,993 total
includes taxes & fees
Aug 26 - Aug 27
The Farmhouse Loft "Greene County's Guesthouse"
Dining

8. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (221 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
The price is ￥20,570
￥39,407 total
includes taxes & fees
Aug 24 - Aug 25
Peaceful, Country Cottage with Open Floor Plan
Dining

9. Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (15 reviews)
"Very Nice house!!! Enjoyed my stay there."
United States
Shaun P.
The price is ￥13,453
￥44,404 total
includes taxes & fees
Aug 23 - Aug 24
Vibey home a few blocks from downtown Hannibal
Property grounds

10. MTL HUNTING LAYAWAY & OUTDOOR HANGOUT

MTL HUNTING LAYAWAY & OUTDOOR HANGOUT
Center
8.8 out of 10, Excellent, (3 reviews)
"Perfect for what we needed for a night. The host replied very efficiently to any questions we had. All that we needed was there. Thank you!!!"
United States
Crystal O.
The price is ￥15,032
￥32,570 total
includes taxes & fees
Sep 2 - Sep 3
MTL HUNTING LAYAWAY & OUTDOOR HANGOUT
Room

11. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
9.0 out of 10, Wonderful, (37 reviews)
"Wonderful place to stay!"
United States
Kari
The price is ￥28,399
￥32,758 total
includes taxes & fees
Aug 23 - Aug 24
Lighthouse Inn & Suites
Interior

12. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.6 out of 10, Exceptional, (60 reviews)
"This place was amazing!"
United States
Nancy S.
The price is ￥23,418
￥36,801 total
includes taxes & fees
Sep 8 - Sep 9
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Exterior detail

13. The Library, a 1-bedroom apartment in Hannibal awaits your visit.

The Library, a 1-bedroom apartment in Hannibal awaits your visit.
Hannibal
9.8 out of 10, Exceptional, (14 reviews)
"Great experience! Lots of space and the hostess thought of everything. We will stay here again when we visit Hannibal. "
United States
Dianna M.
The price is ￥18,988
￥23,928 total
includes taxes & fees
Aug 26 - Aug 27
The Library, a 1-bedroom apartment in Hannibal awaits your visit.
Living area

14. The Nest, reconnect with that special someone in our charming birdhouse!

The Nest, reconnect with that special someone in our charming birdhouse!
Troy
9.4 out of 10, Exceptional, (49 reviews)
"Was very clean, great little spot for a weekend get away. Was everything they said it was."
United States
Dillon E.
The price is ￥26,899
￥32,866 total
includes taxes & fees
Aug 23 - Aug 24
The Nest, reconnect with that special someone in our charming birdhouse!
Interior

15. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.8 out of 10, Exceptional, (22 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
The price is ￥26,630
￥40,787 total
includes taxes & fees
Aug 24 - Aug 25
The John Sydney House - Family and Pet Friendly Historic Home Downtown
Private kitchen

16. Shouse Near Mark Twain Lake!

Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (12 reviews)
"This was our second stay, and it was just as great as the first time! Plenty of room to play, huge TVs for family movie night, and a well equipped kitchen for serving meals. Thank you! "
United States
Christina H.
The price is ￥34,811
￥48,291 total
includes taxes & fees
Aug 23 - Aug 24
Shouse Near Mark Twain Lake!
Dining

17. Historic 2BR Home in Downtown Troy - King Bed, Fire Table & Patio

Historic 2BR Home in Downtown Troy - King Bed, Fire Table & Patio
Troy
10.0 out of 10, Exceptional, (1 review)
"We came in town for the fair and this place was a very beautiful place. Very clean and very well decorated. It was the perfect place to stay in Troy. The host was very nice and could be reached instantly if we had any issues."
United States
Unspecified B.
The price is ￥27,216
￥63,057 total
includes taxes & fees
Sep 10 - Sep 11
Historic 2BR Home in Downtown Troy - King Bed, Fire Table & Patio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Pike County Hotel Reviews

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

10/10 Excellent
"Our stay at Quality Inn and Suites Hannibal was just what we needed for our final leg of our trip home. The suite was an actual 2 room suite and was very spacious. Everything was very clean and the front desk staff was very welcoming and courteous. We stay in Choice Hotel properties every time we can and this was the first time we were welcomed with a snack and a bottle of water. Also, the breakfast was by far the best we have had at any Choice Hotels property we have stayed at."
Mike 1-night trip
Posted 4 hours ago
Quality Inn & Suites Hannibal West

Find out more about Pike County

Vacation Apartments in Pike County

Search for Vacation rentals in Pike County on Expedia! You can easily find your home rentals, villas, Vacation apartments in Pike County using one of the methods below:

  • View our selection of featured Vacation rentals in Pike County
  • Use the map to find apartments and other Vacation homes in the Pike County neighbourhood you prefer
  • Enter your travel dates to view the best deals on Vacation rentals in Pike County while they last

Look no further and take a look at our great range of rental properties in Pike County!