Defiance Vacation Rentals

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Check prices for these dates

In two weeks
Feb 20 - Feb 22
In two months
Apr 3 - Apr 5
In three months
May 1 - May 3
In four months
May 29 - May 31

Our top choices for Defiance vacation rentals

Smart TV, books

Casa de Saint Charles

Casa de Saint Charles
Saint Charles
9.2 out of 10, Wonderful, (17 reviews)
"The home was perfect for our multi-family gathering. There was lots of room for everyone and the location was great for our needs."
United States
Karla Z.
The price is ￥19,495
￥47,795 total
includes taxes & fees
Feb 10 - Feb 11
Casa de Saint Charles
Terrace/patio

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Augusta
10.0 out of 10, Exceptional, (30 reviews)
"Adorable place to stay!"
United States
Amy F.
The price is ￥25,627
￥44,360 total
includes taxes & fees
Feb 10 - Feb 11
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Exterior

TJ’s Country Getaway- Dog Friendly

TJ’s Country Getaway- Dog Friendly
Union
10.0 out of 10, Exceptional, (45 reviews)
"It had everything you need for a relaxing stay. "
United States
Judith
The price is ￥11,634
￥22,639 total
includes taxes & fees
Feb 16 - Feb 17
TJ’s Country Getaway- Dog Friendly
Smart TV, books

The Robins Nest by Innsbrook Vacations!

The Robins Nest by Innsbrook Vacations!
Innsbrook
9.6 out of 10, Exceptional, (5 reviews)
"Amazing place and property nearby, the overflow from lake is a must see . Just like a waterfall"
United States
John S.
The price is ￥29,576
￥81,745 total
includes taxes & fees
Mar 8 - Mar 9
The Robins Nest by Innsbrook Vacations!
Interior

Tamm Loft | River view, Downtown WashMo, Dog-friendly

Tamm Loft | River view, Downtown WashMo, Dog-friendly
Washington
10.0 out of 10, Exceptional, (18 reviews)
"This is a beautiful place , well equipped kitchen . It was very clean too . It has located downtown and many restaurants in walking distance"
United States
Johanna D.
The price is ￥39,456
￥49,908 total
includes taxes & fees
Feb 10 - Feb 11
Tamm Loft | River view, Downtown WashMo, Dog-friendly
Exterior

Rustic Augusta Cabin by StayLage

Rustic Augusta Cabin by StayLage
Augusta
9.2 out of 10, Wonderful, (5 reviews)
"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "
United States
teresa s.
The price is ￥19,017
￥49,483 total
includes taxes & fees
Feb 10 - Feb 11
Rustic Augusta Cabin by StayLage
Interior

Adorable Augusta Cabin

Adorable Augusta Cabin
Augusta
9.0 out of 10, Wonderful, (10 reviews)
"Absolutely beautiful area. Cabin is so cozy"
United States
Aaron
The price is ￥13,923
￥32,752 total
includes taxes & fees
Feb 10 - Feb 11
Adorable Augusta Cabin
Fridge, microwave, oven, stovetop

The Hidden Gem - 2BR Basement Apartment on 7 Acres

The Hidden Gem - 2BR Basement Apartment on 7 Acres
Moscow Mills
10.0 out of 10, Exceptional, (12 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is ￥21,618
￥43,943 total
includes taxes & fees
Feb 10 - Feb 11
The Hidden Gem - 2BR Basement Apartment on 7 Acres
Interior

Spacious Cottage on Main st- Near Downtown

Spacious Cottage on Main st- Near Downtown
St. Charles Historic District
10.0 out of 10, Exceptional, (7 reviews)
"The house was perfect. Clean, organized and portrayed exactly as in the pictures. We loved our stay here. The host was punctual and attentive to all questions. We would definitely stay again. "
United States
Theresa P.
The price is ￥14,150
￥33,016 total
includes taxes & fees
Feb 10 - Feb 11
Spacious Cottage on Main st- Near Downtown
TV

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
St. Charles Historic District
9.4 out of 10, Exceptional, (13 reviews)
"House was beautiful. Very nice quiet stay"
United States
Amy S.
The price is ￥13,993
￥37,019 total
includes taxes & fees
Feb 10 - Feb 11
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
Bar (on property)

Aspen Sights by Innsbrook Vacations!

Aspen Sights by Innsbrook Vacations!
Innsbrook
9.6 out of 10, Exceptional, (13 reviews)
"Lovely weekend- enjoyed checking out Innsbrook"
United States
Denise L.
The price is ￥10,985
￥34,265 total
includes taxes & fees
Feb 10 - Feb 11
Aspen Sights by Innsbrook Vacations!
2 bedrooms, desk, iron/ironing board, free WiFi

Spacious Townhome Retreat by StayLage

Spacious Townhome Retreat by StayLage
O Fallon
9.8 out of 10, Exceptional, (10 reviews)
"Great quiet neighborhood close to everything!"
United States
Jen D.
The price is ￥21,055
￥60,885 total
includes taxes & fees
Feb 10 - Feb 11
Spacious Townhome Retreat by StayLage
Property grounds

The Ridge by Innsbrook Vacations!

The Ridge by Innsbrook Vacations!
Innsbrook
9.6 out of 10, Exceptional, (22 reviews)
"Adorable property in an amazing resort community. Beds were comfortable, house was stocked with everything we needed. Had an amazing time!"
United States
Stephanie S.
The Ridge by Innsbrook Vacations!
Fridge, microwave, oven, stovetop

4 Bedroom Wentzville Home by StayLage

4 Bedroom Wentzville Home by StayLage
Wentzville
9.8 out of 10, Exceptional, (6 reviews)
"Amazing for attending the fireworks festivals nearby. Great shops walking distance for coffee and food"
United States
Tom K.
The price is ￥27,337
￥79,202 total
includes taxes & fees
Feb 23 - Feb 24
4 Bedroom Wentzville Home by StayLage
Pool

VRBO Brick House of Washington

VRBO Brick House of Washington
Washington
10.0 out of 10, Exceptional, (16 reviews)
"Beautiful, comfy, huge, amazing pool and very kind hosts. A great spot to get together with old friends and their kids of all ages."
United States
Allison D.
The price is ￥33,960
￥92,847 total
includes taxes & fees
Feb 10 - Feb 11
VRBO Brick House of Washington
Interior

Beautiful+Spacious+FencedYard🐕Grill+Patio+Walk2Park+27MileBikeTrail🚴‍♀️

Beautiful+Spacious+FencedYard🐕Grill+Patio+Walk2Park+27MileBikeTrail🚴‍♀️
St. Peters
10.0 out of 10, Exceptional, (23 reviews)
"Clean and close to everything you would want for a stay ."
United States
Judy H.
The price is ￥32,545
￥63,360 total
includes taxes & fees
Feb 22 - Feb 23
Beautiful+Spacious+FencedYard🐕Grill+Patio+Walk2Park+27MileBikeTrail🚴‍♀️
Bar (on property)

Lake Aspen Hideaway by Innsbrook Vacations!

Lake Aspen Hideaway by Innsbrook Vacations!
Wright City
9.8 out of 10, Exceptional, (21 reviews)
"Check-in was easy and property was clean. Great place to stay!"
United States
Casey A.
The price is ￥10,985
￥34,265 total
includes taxes & fees
Feb 10 - Feb 11
Lake Aspen Hideaway by Innsbrook Vacations!
Property amenity

Landing Apartments - Eureka

Landing Apartments - Eureka
4.0 star property
Eureka
Landing Apartments - Eureka
Smart TV

Woodland Retreat with a Swim Spa

Woodland Retreat with a Swim Spa
Innsbrook
9.6 out of 10, Exceptional, (23 reviews)
"Plenty of room for the 6 of us "
United States
Missy G.
The price is ￥28,300
￥62,560 total
includes taxes & fees
Feb 10 - Feb 11
Woodland Retreat with a Swim Spa
Smart TV

Cozy Unit on Historic Main Street

Cozy Unit on Historic Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (11 reviews)
"Wonderful host and accomodations !"
United States
Matthew K.
The price is ￥15,981
￥35,791 total
includes taxes & fees
Feb 15 - Feb 16
Cozy Unit on Historic Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Everything was very, very nice. The casino smoke was unfortunate, but was not noticable in the room, of course."
shawn 1-night trip
Posted 1 day ago
Hollywood Casino & Hotel St. Louis

Find out more about Defiance

Search for holiday rentals in Defiance on Expedia! You can easily find your home rentals, villas, holiday apartments in Defiance using one of the methods below:

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Look no further and take a look at our great range of rental properties in Defiance!

Frequently asked questions

Can I find vacation rentals in Defiance?

Yes, there are vacation rentals close to popular sights in Defiance, or you can choose a more secluded option if you're looking for relaxation. Defiance is known for its wineries and parks.

What are some of the best vacation home rentals that Defiance has to offer?

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟: This vacation home rental outside of Defiance offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop.

How many vacation rentals will I find in Defiance?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Defiance stay.

What’s there to see and do in Defiance?

Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. Other places in town to visit include Yellow Farmhouse Winery and Chandler Hill Vineyards.

What’s a vacation rental in Defiance like?

A vacation rental is a private property where you can stay for a few weeks or just a few days in Defiance. Vacation rentals feature amenities like laundry facilities and kitchens so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great option for families.