Centro Histórico Vacations
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Where to stay in Centro Histórico
Find the best Centro Histórico areas and neighborhoods for the activities you enjoy most. Learn more about Centro Histórico
Equipetrol
Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.
Hamacas
While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.
Zona Sur (South Zone)
Zona Sur (South Zone) might not have many top sights, but Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre are two attractions nearby that you can check out.
Urubó
While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.
Centro Histórico Hotel Deals
Lido Hotel
Calle 21 de Mayo 527 Santa Cruz
￥3,677
￥3,677 total
Nov 9 - Nov 10
Hotel Las Américas
Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department
Fully refundableReserve now, pay when you stay
￥3,681
￥3,681 total
Oct 26 - Oct 27
8/10 Very Good! (35 reviews)
"Great place for the price. Only issue I had was the music blaring one of two nights across the street - all night, from 9pm to 6am. Not the hotels fault; but frustrating. Would stay again though"
Reviewed on Oct 22, 2026
Cosmopolitano Hotel Boutique
Pari, 70 Santa Cruz
￥8,289
￥8,289 total
Nov 16 - Nov 17
9.2/10 Wonderful! (138 reviews)
"Good location. I had tour the next day, they helped me prepare my breakfast takeaway. Nice"
Reviewed on Oct 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Centro Histórico attractions
Plaza 24 de Septiembre
8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
San Lorenzo Cathedral
9.0/10 (84 reviews)
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
Arenal Park
7.4/10 (16 reviews)
After visiting Arenal Park, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.
La Recova Artisan Walk
8.8/10 (20 reviews)
During your trip to Santa Cruz, you can search for that perfect souvenir at La Recova Artisan Walk. Make some time to visit the cathedral while you're in the area.
Artecampo
8.8/10 (12 reviews)
During your trip to Santa Cruz, you can enjoy retail therapy at Artecampo. Make some time to visit the cathedral while you're in the area.
Ethno-folkloric Museum
9.0/10 (16 reviews)
You can spend an afternoon studying the exhibits at Ethno-folkloric Museum during your trip to Santa Cruz. While in the area, you can find time to visit its shops.
Sacred Art Museum
8.8/10 (10 reviews)
You can spend an afternoon exploring the galleries in Sacred Art Museum in Santa Cruz. While in the area, you can find time to visit its shops.
Guarani Nandereko Nomai Art and Culture Center
9.4/10 (3 reviews)
Enjoy an outing to Guarani Nandereko Nomai Art and Culture Center during your stay in Santa Cruz. While in the area, you can find time to visit its shops.
Things to do
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
￥13,335
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
￥46,907
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
￥125,347
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.