An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

Find hotels in San Antonio, Cali

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Jul 10 - Jul 12
In two weeks
Jul 17 - Jul 19

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Property class

Our top choices for San Antonio hotels

Exterior

Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (238 reviews)
"Good breakfast included‼️ helpful stuff"
United States
Andrea
The price is ￥18,938
￥18,938 total
Jul 5 - Jul 6
Alko Hotel Casa Nispero
Garden view

Casa Ruta Sur

Casa Ruta Sur
3.0 star property
San Antonio
9.8 out of 10, Exceptional, (31 reviews)
"Great location in Cali, close to everything. Friendly host and quiet place to rest."
United States
Arthur
The price is ￥11,413
￥11,413 total
Jul 13 - Jul 14
Casa Ruta Sur
Reception

San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (68 reviews)
"Gracious folks. Helpful and clean and not fancy. 5 star service. Will consider this again if I am back. "
United States
Nirmal Arogyaswami
The price is ￥12,631
￥15,533 total
Jul 22 - Jul 23
San Antonio Hotel Boutique
Double Room | Hypo-allergenic bedding, desk, free WiFi, bed sheets

HOTEL ALTANA

HOTEL ALTANA
3.0 star property
San Antonio
8.0 out of 10, Very Good, (2 reviews)
"The staff is very courteous. The breakfast is simple but delicious . The room was clean, spacious and with excellent AC. The only thing to consider is that there is a very cannabis friendly bar downstairs in the lobby area and you walk through it to get to your room. The rooms do not smell of cannabis but you walk through a lot of it. "
United States
Eva
The price is ￥7,260
￥23,394 total
Jul 5 - Jul 6
HOTEL ALTANA
Standard Single Room | Living area

Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
9.2 out of 10, Wonderful, (5 reviews)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is ￥8,756
￥8,756 total
Aug 1 - Aug 2
Hotel Casa Bresse
Restaurant

Viajero Cali Hostel & Salsa School

Viajero Cali Hostel & Salsa School
2.0 star property
San Antonio
8.8 out of 10, Excellent, (63 reviews)
"Excellent stay. I stayed in a private room which was small, basic but comfortable. The staff were friendly. The hostel is in a excellent location close to restaurants, bars and attractions. The extra activities and the salsa school were amazing."
Australia
Jasmine
The price is ￥7,976
￥7,976 total
Jul 6 - Jul 7
Viajero Cali Hostel & Salsa School
Full-size fridge, microwave, blender, cookware/dishes/utensils

Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is ￥3,375
￥3,375 total
Jul 12 - Jul 13
Epifania Guest House
Interior

Casa feliz

Casa feliz
1.0 star property
San Antonio
The price is ￥2,544
￥2,544 total
Jul 12 - Jul 13
Casa feliz
Interior

casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
4.0 out of 10, (2 reviews)
"Cheap and convenient location. But mosquitoes in room every night and leaky toilet. There are better options available. "
Australia
Meyer
The price is ￥2,786
￥2,786 total
Jul 7 - Jul 8
casa hostal ave maria san antonio cali
Outdoor pool

Hotel Boutique Iyarí

Hotel Boutique Iyarí
3.0 star property
27.7 km from San Antonio
The price is ￥7,750
￥7,750 total
Jul 5 - Jul 6
Hotel Boutique Iyarí
View from property

Hotel Campestre El Molino Dapa Cali

Hotel Campestre El Molino Dapa Cali
3.0 star property
10.3 km from San Antonio
8.0 out of 10, Very Good, (19 reviews)
"Vwry good "
Canada
David
The price is ￥9,453
￥9,453 total
Jul 11 - Jul 12
Hotel Campestre El Molino Dapa Cali
2 outdoor pools

Hotel Real Elim International

Hotel Real Elim International
4.5 star property
18.9 km from San Antonio
8.8 out of 10, Excellent, (357 reviews)
"Family friendly and great staff."
United States
Roxana
The price is ￥16,673
￥16,673 total
Jul 19 - Jul 20
Hotel Real Elim International
In-room safe, laptop workspace, iron/ironing board, free WiFi

HOTEL AIKOS

HOTEL AIKOS
3.0 star property
5.9 km from San Antonio
The price is ￥9,743
￥9,743 total
Jul 6 - Jul 7
HOTEL AIKOS
Reception

Casa Aurora Luxury Hotel

Casa Aurora Luxury Hotel
3.0 star property
12.2 km from San Antonio
8.6 out of 10, Excellent, (4 reviews)
"Hotel precioso, con habitaciones de lujo en todo sentido"
Mexico
Sebastián
The price is ￥13,668
￥13,668 total
Jul 7 - Jul 8
Casa Aurora Luxury Hotel
Exterior

Hotel On By Zenya Host

Hotel On By Zenya Host
4.0 star property
El Peñon, 0.5 km from San Antonio
The price is ￥4,843
￥4,843 total
Jul 7 - Jul 8
Hotel On By Zenya Host
Front of property - evening/night

Hotel Pance 122

Hotel Pance 122
3.5 star property
11.6 km from San Antonio
8.8 out of 10, Excellent, (46 reviews)
"Amazing stay!!"
United States
Jahiem
The price is ￥15,131
￥15,131 total
Jul 12 - Jul 13
Hotel Pance 122
Exterior

Tru By Hilton Cali Sur

Tru By Hilton Cali Sur
2.5 star property
10 km from San Antonio
9.0 out of 10, Wonderful, (103 reviews)
"Great place to stay"
United States
Mario
The price is ￥11,029
￥11,029 total
Jul 31 - Aug 1
Tru By Hilton Cali Sur
Reception

Mirago Hotel

Mirago Hotel
2.5 star property
6 km from San Antonio
7.2 out of 10, Good, (10 reviews)
The price is ￥10,429
￥10,429 total
Aug 3 - Aug 4
Mirago Hotel
Free WiFi, bed sheets

La Villa The View

La Villa The View
3.0 star property
13.2 km from San Antonio
8.0 out of 10, Very Good, (1 review)
The price is ￥7,500
￥7,500 total
Jul 15 - Jul 16
La Villa The View
Standard Room, Multiple Beds | Living area | 42-inch TV with cable channels

Hotel Thama Palmira

Hotel Thama Palmira
3.0 star property
28 km from San Antonio
8.2 out of 10, Very Good, (96 reviews)
"The staff was very nice and helpful The hotel location was Perfect i like the the hotel was very clean "
United States
Margarita
The price is ￥7,731
￥7,731 total
Jul 11 - Jul 12
Hotel Thama Palmira
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Antonio

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Garden view
Casa Ruta Sur
3.0 star property
9.8
Exceptional
31 reviews
View
Exterior
Alko Hotel Casa Nispero
4.0 star property
9.4
Exceptional
238 reviews
View
Restaurant
Viajero Cali Hostel & Salsa School
2.0 star property
8.8
Excellent
63 reviews
View
Reception
San Antonio Hotel Boutique
3.0 star property
9.2
Wonderful
68 reviews
View
Standard Single Room | Living area
Hotel Casa Bresse
2.5 star property
9.2
Wonderful
5 reviews
View

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.
A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

When in El Peñon, you can plan a visit to El Gato Del Rio and Gato de Tejada Monument, some noteworthy sights in the nearby area.

Pance

Pance might not have many top sights, but Chorrera del Indio and Los Arrayanes Recreational Center are two attractions nearby that you can check out.

Top San Antonio Hotel Reviews

Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels

8/10 Good
"The room was big and spacious. The staff is very nice and helpful. The breakfast is very good and the location is great. The only issue I have weee that the WiFi and the hot water didn’t work in my room. I had to reservations because we traveled from Cali to El Eje Cafetero. The room I had for the first 3 days WiFi didn’t work and the room I had after we came back from El Eje the hot water wasn’t working."
Ana Karina 3-night trip
Posted less than an hour ago
Hotel el Peñón By Bithotels

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Other good options for your stay in the area include Viajero Cali Hostel & Salsa School and San Antonio Hotel Boutique.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 50 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.

Explore a world of travel with Expedia