What's it like in San Antonio?

Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.

What's a favorite place to stay in San Antonio?

Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Another good option for your stay in the area is Viajero Cali Hostel & Salsa School .

How many hotels should I expect to find in the San Antonio area?

If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Antonio, will I receive a refund?

Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.

Where can I learn more about changing or cancelling my trip to San Antonio?

For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page .

What can I see and do in this Cali neighborhood?

Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.

Top San Antonio Hotels

An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

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Our top choices for San Antonio hotels

An outdoor patio with a glass table and chairs, surrounded by lush greenery and illuminated by green lighting.

1. Alko Hotel Casa Nispero

San Antonio

ALVARO

￥16,024 total

Oct 18 - Oct 19

A modern living room with a sofa, a coffee table, and decorative items.

2. Hotel habitat san antonio

San Antonio

Giovanny

￥7,979 total

Oct 17 - Oct 18

A lobby with a fountain, indoor plants, a dining area, and a painting of a house on the wall.

3. San Antonio Hotel Boutique

San Antonio

Jung

￥13,495 total

Nov 4 - Nov 5

An indoor dining area with tables and chairs, surrounded by hanging plants and greenery.

4. Viajero Cali Hostel & Salsa School

San Antonio

Jasmine

￥9,150 total

Nov 16 - Nov 17

A room with two beds, a blue wall, a door, and a window.

5. Our Home San Antonio

San Antonio

gloria

￥7,529 total

Nov 5 - Nov 6

A modern kitchen with a central island, two wicker bar stools, a red pendant light, and a large window with a view.

6. Epifania Guest House

San Antonio

David Alejandro

￥3,159 total

Oct 25 - Oct 26

A courtyard with a wooden table and chairs, surrounded by potted plants and a climbing plant wall.

7. Hotel Casa Bresse

San Antonio

Stanislaw

￥7,270 total

Oct 19 - Oct 20

A hallway with a large potted plant, a wooden bench, and a chandelier.

8. Casa feliz

San Antonio

￥2,442 total

Nov 1 - Nov 2

A stone fountain with a child statue, surrounded by potted plants and a tiled wall with a window and a framed picture.

9. casa hostal ave maria san antonio cali

San Antonio

Meyer

￥2,560 total

Oct 29 - Oct 30

A swimming pool with a tiled deck, a dining area with chairs and a table, and a wall decorated with posters.

10. hotel boutique casa vecchia

0.4 km from San Antonio

carolina

￥6,597 total

Oct 19 - Oct 20

A hotel with a modern facade, a prominent sign, and a landscaped entrance area.

11. InterContinental Cali by IHG

El Peñon, 0.3 km from San Antonio

Pedro

￥20,711 total

Nov 16 - Nov 17

A modern hotel with a flat facade, balconies with plants, and a visible entrance.

12. Hotel Foresto 365

El Peñon, 0.5 km from San Antonio

Axel

￥8,896 total

Oct 17 - Oct 18

A hotel lobby with a grand chandelier, seating area, and a decorative plant centerpiece.

13. Hotel Dann Carlton Cali

El Peñon, 0.4 km from San Antonio

Sarah

￥14,733 total

Oct 25 - Oct 26

A multi-story hotel with a prominent '007' sign, a restaurant named 'Cooks', and a well-lit entrance area with potted plants.

14. Sonesta Hotel Cali

1.6 km from San Antonio

Luis

￥17,019 total

Oct 17 - Oct 18

A modern outdoor patio area with a staircase leading to an upper level, a seating area with chairs, and a bar counter.

15. Hampton by Hilton Cali, Colombia

1.1 km from San Antonio

Michael

￥12,468 total

Oct 25 - Oct 26

A restaurant with outdoor seating, a brick wall, and hanging lights.

16. Hotel el Peñón By Bithotels

El Peñon, 0.4 km from San Antonio

ross

￥10,463 total

Oct 26 - Oct 27

A modern indoor space with hanging wicker lamps, large windows, and indoor plants.

17. Now Hotel Cali - Adults Only

Juanambú, 1.1 km from San Antonio

Osvaldo

￥11,192 total

Oct 18 - Oct 19

A modern building with a glass facade, a tree in front, and a sign reading "Cr3A D4-62".

18. Altio hotel

El Peñon, 0.7 km from San Antonio

Manuel

￥6,448 total

Oct 18 - Oct 19

A dining area with wooden chairs and tables, a central plant, and wall-mounted lights.

19. NH Boulevard Del Río Cali

Centenario, 0.7 km from San Antonio

Regis

￥11,374 total

Oct 25 - Oct 26

A spacious lobby with a beige sofa, a chandelier, and a reception desk.

20. Hotel Obelisco

El Peñon, 0.7 km from San Antonio

James

￥13,069 total

Nov 3 - Nov 4

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Compare popular hotels in San Antonio

Property	Star rating	Guest rating
Alko Hotel Casa Nispero	4.0 star property	9.4 Exceptional 249 reviews	View
San Antonio Hotel Boutique	3.0 star property	9.2 Wonderful 69 reviews	View
Hotel Casa Bresse	2.5 star property	9.2 Wonderful 5 reviews	View
Viajero Cali Hostel & Salsa School	2.0 star property	9.0 Wonderful 70 reviews	View
casa hostal ave maria san antonio cali	2.0 star property	4.0 2 reviews	View

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.

A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

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A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

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An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

When in El Peñon, you can plan a visit to Gato de Tejada Monument and Calima Gold Museum of the Bank of the Republic, some noteworthy sights in the nearby area.

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Pance

Pance might not have many top sights, but Chorrera del Indio and Los Arrayanes Recreational Center are two attractions nearby that you can check out.

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Las Vegas

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Top San Antonio Hotel Reviews

Hotel Spirito by Spiwak

10/10 Excellent

"Todo estuvo bien nos atendimos bien"

MS Pacífico Chipichape Plus

10/10 Excellent

"We had a great stay at this hotel while traveling with our family. We booked two rooms, and everything was clean and comfortable. The staff was very friendly and always willing to help. Breakfast was included and was good, although a little more variety would have been nice. The location was excellent! We were within walking distance of chipichape, exito, restaurants, pharmacies, small grocery stores., which made everything more convenient. Overall we really enjoyed our stay and would definitely recommend this hotel to other families visiting the area. We would happily stay here again!"

San Antonio Hotel Boutique

10/10 Excellent

"I had an enjoyable albeit short (3 nights) stay at the San Antonio Hotel Boutique. Unfortunately, I left my phone in the taxi that dropped me off but Fonseco at the front desk was very helpful in trying to locate the driver. Although we were unable to contact him, I have since been in touch with someone who has the phone and am coordinating its return to the US. Both of the hotel proprietors, Ricardo and Nelson, were also extremely helpful and fluent English speakers. My room had a safe and was very comfortable and quiet, and came with breakfast each morning, with a selection that included eggs, ham, cheese, toast, coffee/chocolate/tea, juice and fruit. The San Antonio neighborhood was safe to walk around with excellent restaurants, art galleries, cafes and shops within walking distance - I visited and would recommend for dining La Boheme, Primos, and the Valle Pacific Ancestral Restaurante (shoutout to my server Dayana!). I was in Cali for a short side trip from Bogata in between dental clinic appointments and would have been more adventurous and explored more of the city but the short duration of my stay and not having a phone limited my choices. I also enjoyed the warmer weather compared to Bogota and definitely hope to go back some day for a longer visit!"

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Our top choices for San Antonio hotels

1. Alko Hotel Casa Nispero

2. Hotel habitat san antonio

3. San Antonio Hotel Boutique

4. Viajero Cali Hostel & Salsa School

5. Our Home San Antonio

6. Epifania Guest House

7. Hotel Casa Bresse

8. Casa feliz

9. casa hostal ave maria san antonio cali

10. hotel boutique casa vecchia

11. InterContinental Cali by IHG

12. Hotel Foresto 365

13. Hotel Dann Carlton Cali

14. Sonesta Hotel Cali

15. Hampton by Hilton Cali, Colombia

16. Hotel el Peñón By Bithotels

17. Now Hotel Cali - Adults Only

18. Altio hotel

19. NH Boulevard Del Río Cali

20. Hotel Obelisco

Compare popular hotels in San Antonio

Where to stay in San Antonio

Ciudad Jardín

Granada

El Peñon

Pance

Las Vegas

Top San Antonio Hotel Reviews

Hotel Spirito by Spiwak

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