An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

Find hotels in San Antonio, Cali

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for San Antonio hotels

A lobby with a fountain, indoor plants, a dining area, and a painting of a house on the wall.

1. San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (69 reviews)
"The location was excellent, within close distance to many good restaurants. The breakfast was good, with fruit and made to order eggs. The AC was quite adequate. "
United States
Jung
The price is ￥12,205
￥12,205 total
Sep 11 - Sep 12
San Antonio Hotel Boutique
An outdoor patio with a glass table and chairs, surrounded by lush greenery and illuminated by green lighting.

2. Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (242 reviews)
"Very friendly staff and very helpful"
United States
Juan
The price is ￥22,702
￥22,702 total
Sep 6 - Sep 7
Alko Hotel Casa Nispero
An indoor garden with a brick archway leading to a seating area with a sofa and a coffee table.

3. Casa Ruta Sur

Casa Ruta Sur
3.0 star property
San Antonio
9.8 out of 10, Exceptional, (31 reviews)
"Great location in Cali, close to everything. Friendly host and quiet place to rest."
United States
Arthur
The price is ￥8,822
￥8,822 total
Oct 2 - Oct 3
Casa Ruta Sur
A courtyard with a wooden table and chairs, surrounded by potted plants and a climbing plant wall.

4. Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
9.2 out of 10, Wonderful, (5 reviews)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is ￥7,628
￥7,628 total
Sep 11 - Sep 12
Hotel Casa Bresse
An indoor dining area with tables and chairs, surrounded by hanging plants and greenery.

5. Viajero Cali Hostel & Salsa School

Viajero Cali Hostel & Salsa School
2.0 star property
San Antonio
9.0 out of 10, Wonderful, (68 reviews)
"Excellent stay. I stayed in a private room which was small, basic but comfortable. The staff were friendly. The hostel is in a excellent location close to restaurants, bars and attractions. The extra activities and the salsa school were amazing."
Australia
Jasmine
The price is ￥8,797
￥8,797 total
Sep 2 - Sep 3
Viajero Cali Hostel & Salsa School
A hallway with a large potted plant, a wooden bench, and a chandelier.

6. Casa feliz

Casa feliz
1.0 star property
San Antonio
The price is ￥2,426
￥2,426 total
Sep 11 - Sep 12
Casa feliz
A modern kitchen with a central island, two wicker bar stools, a red pendant light, and a large window with a view.

7. Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is ￥3,358
￥3,358 total
Sep 2 - Sep 3
Epifania Guest House
A stone fountain with a child statue, surrounded by potted plants and a tiled wall with a window and a framed picture.

8. casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
4.0 out of 10, (2 reviews)
"Cheap and convenient location. But mosquitoes in room every night and leaky toilet. There are better options available. "
Australia
Meyer
The price is ￥2,588
￥2,588 total
Sep 9 - Sep 10
casa hostal ave maria san antonio cali
A restaurant with outdoor seating, a brick wall, and hanging lights.

9. Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels
4.0 star property
El Peñon, 0.4 km from San Antonio
9.0 out of 10, Wonderful, (472 reviews)
"Great location and staff and hotel just right"
United States
Avadawn
The price is ￥11,555
￥11,555 total
Sep 27 - Sep 28
Hotel el Peñón By Bithotels
A hotel lobby with a grand chandelier, seating area, and a decorative plant centerpiece.

10. Hotel Dann Cali

Hotel Dann Cali
3.0 star property
El Peñon, 0.4 km from San Antonio
8.6 out of 10, Excellent, (605 reviews)
"Hotel is within walking distance to many attractions."
United States
Helen
The price is ￥15,189
￥15,189 total
Sep 4 - Sep 5
Hotel Dann Cali

11. Passiflora luxury suite

Passiflora luxury suite
3.0 star property
1 km from San Antonio
10.0 out of 10, Exceptional, (1 review)
"No suggestions"
United States
Michelle
The price is ￥5,098
￥7,495 total
Sep 2 - Sep 3
Passiflora luxury suite
A spacious lobby with a reception desk, chandeliers, and a large marble floor.

12. InterContinental Cali by IHG

InterContinental Cali by IHG
4.0 star property
El Peñon, 0.3 km from San Antonio
9.0 out of 10, Wonderful, (1,002 reviews)
"Very good hotel and staff"
United States
Pedro
The price is ￥21,132
￥21,132 total
Sep 12 - Sep 13
InterContinental Cali by IHG
A spacious lobby with a beige sofa, a chandelier, and a reception desk.

13. Hotel Obelisco

Hotel Obelisco
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (542 reviews)
"Hotel was really good, the best is the location, breakfast by the river, they have a terrace restaurant across the street by the river. walking distance from every thing, very happy"
United States
Fernando
The price is ￥11,130
￥11,130 total
Sep 18 - Sep 19
Hotel Obelisco
A historic building with a central courtyard, stone steps, and a traditional balcony.

14. Hotel Stein Colonial

Hotel Stein Colonial
3.0 star property
Juanambú, 0.6 km from San Antonio
9.4 out of 10, Exceptional, (270 reviews)
"Super friendly staff, beautiful historic hotel, & great location/breakfast!"
United States
kevin
The price is ￥9,064
￥9,064 total
Sep 20 - Sep 21
Hotel Stein Colonial
A modern building with a glass facade, a tree in front, and a sign reading "Cr3A D4-62".

15. Altio hotel

Altio hotel
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (191 reviews)
"it was ok. room had no view to outside. Good place to rest for the night but for me I wouldn't want a long stay there."
United States
Eric
The price is ￥7,992
￥7,992 total
Sep 6 - Sep 7
Altio hotel
A building with red and white exterior walls, a tiled roof, and a brick-paved entrance.

16. Laundry House

Laundry House
2.0 star property
El Peñon, 0.3 km from San Antonio
The price is ￥2,411
￥2,411 total
Oct 2 - Oct 3
Laundry House
A rooftop pool area with lounge chairs, a hot tub, and tropical plants.

17. Veca Flats Centenario

Veca Flats Centenario
4.0 star property
Juanambú, 0.7 km from San Antonio
9.0 out of 10, Wonderful, (16 reviews)
"Really awesome place staff was wonderful ⭐️👍"
United States
Danny Carlos
The price is ￥11,034
￥11,034 total
Sep 6 - Sep 7
Veca Flats Centenario
A dining area with wooden chairs and tables, a central plant, and wall-mounted lights.

18. NH Boulevard Del Río Cali

NH Boulevard Del Río Cali
3.5 star property
Centenario, 0.7 km from San Antonio
9.0 out of 10, Wonderful, (379 reviews)
"Good location and staff is very helpful."
United States
David
The price is ￥11,633
￥11,633 total
Sep 19 - Sep 20
NH Boulevard Del Río Cali
A modern hotel with a flat facade, balconies with plants, and a visible entrance.

19. Hotel Foresto 365

Hotel Foresto 365
4.0 star property
El Peñon, 0.5 km from San Antonio
9.4 out of 10, Exceptional, (69 reviews)
"Staff was super friendly."
United Kingdom
Axel
The price is ￥11,777
￥11,777 total
Sep 4 - Sep 5
Hotel Foresto 365
A hotel lobby with a grand chandelier, seating area, and a decorative plant centerpiece.

20. Hotel Dann Carlton Cali

Hotel Dann Carlton Cali
3.5 star property
El Peñon, 0.4 km from San Antonio
8.8 out of 10, Excellent, (480 reviews)
"Loved our stay!"
United States
Doris
The price is ￥15,969
￥15,969 total
Sep 25 - Sep 26
Hotel Dann Carlton Cali
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Antonio

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
An indoor garden with a brick archway leading to a seating area with a sofa and a coffee table.
Casa Ruta Sur
3.0 star property
9.8
Exceptional
31 reviews
View
An outdoor patio with a glass table and chairs, surrounded by lush greenery and illuminated by green lighting.
Alko Hotel Casa Nispero
4.0 star property
9.4
Exceptional
242 reviews
View
A lobby with a fountain, indoor plants, a dining area, and a painting of a house on the wall.
San Antonio Hotel Boutique
3.0 star property
9.2
Wonderful
69 reviews
View
A courtyard with a wooden table and chairs, surrounded by potted plants and a climbing plant wall.
Hotel Casa Bresse
2.5 star property
9.2
Wonderful
5 reviews
View
An indoor dining area with tables and chairs, surrounded by hanging plants and greenery.
Viajero Cali Hostel & Salsa School
2.0 star property
9.0
Wonderful
68 reviews
View

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.
A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

When in El Peñon, you can plan a visit to Centenario Commercial Center and El Gato Del Rio, some noteworthy sights in the nearby area.

Rozo

Check out nearby sights like Fenix Air Museum while you're spending some time in Rozo and the surrounding area.

Top San Antonio Hotel Reviews

Cali Marriott Hotel

Cali Marriott Hotel

10/10 Excellent
"NO NEED"
jose 2-night trip
Posted 8 hours ago
Cali Marriott Hotel

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Another good option for your stay in the area is Viajero Cali Hostel & Salsa School.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.

Explore a world of travel with Expedia