St. Catherine of Siena, the saint who prayed at the Basilica di San Domenico and whose relics are still here, fundamentally altered the course of history for the Catholic Church. One of the most famous mystics of her age, St. Catherine is credited, at least partially, with ending the Western Schism that had seen the papacy divided into two. Her own religious faith began in this 13th-century basilica, which stood near the working-class neighborhood where she grew up. Visit Basilica di San Domenico to see the saint’s relics or just come to appreciate the impressive medieval art and architecture preserved here.

Climb Camporegio hill, where the basilica sits overlooking a valley and the Fontebranda district where the saint spent her early years. Admire the basilica’s impressive brickwork, typical of churches built at the time. Walk around to the side entrance, the only point of entry to a church that has been damaged by fire, earthquake and Spanish occupation. Enter directly into the Capella della Volte, the basilica’s largest chapel and the setting for many of Catherine’s visions.

Wander around the church’s interior, which is set out in an Egyptian cross plan and is marked by the gothic expansion that took place in the 14th century. Pay respects to Catherine’s relics, notably her preserved head and thumb, in the St. Catherine Chapel, which also features the only painting of her made during her lifetime. There’s also a chain that is thought to have been used by the saint for flagellation.

The Basilica di San Domenico is located in Siena's Historical Center, right above the Fontebranda. Travel here by bus from the train station in just over 10 minutes or walk in about 20 minutes. The Duomo is a 10-minute walk away. If you drive, use the dedicated metered underground parking garage.

The basilica is freely open to visitors daily from morning to evening, with slight seasonal variations. Check online for Mass schedules. All visitors to the basilica must have their shoulders covered.