A signpost with distance markers for Chicago and Los Angeles.

Find hotels in Adrian, TX from ￥12,267

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Filter by

Property class

Guest rating

Our top choices for Adrian hotels

Lobby
Room
View from property
Reception

1. Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn
Vega
United States
Niki
￥10,951
￥12,267 total
includes taxes & fees
Sep 12 - Sep 13
Route 66 Desert Rose Country Inn
Pool
Room
Exterior
Bathroom

2. Days Inn by Wyndham Vega TX

Days Inn by Wyndham Vega TX
Vega
United States
Gerald
￥14,079
￥15,768 total
includes taxes & fees
Sep 10 - Sep 11
Days Inn by Wyndham Vega TX
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Adrian attractions

Midway Point of Route 66

Stand at the exact midpoint of Route 66, where Chicago and Los Angeles are precisely 1,139 miles away. The historic Midpoint Café serves "ugly crust pies" in the spot that inspired Flo's V8 Café in Pixar's "Cars."
See properties

Learn more about Adrian

At the midpoint of Route 66, stop at the Midpoint Café for their famous 'ugly crust' pies and Route 66 memorabilia. Snap a photo with the town's midway marker, then chat with locals who'll share stories about this tiny highway community.

See all hotels in Adrian
A signpost with distance markers for Chicago and Los Angeles.

Top Adrian Hotel Reviews

Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn

10/10 Excellent
"Clean rooms, comfortable beds"
Jahdid 1-night trip
Posted 11 hours ago
Route 66 Desert Rose Country Inn

More cheap stays in Adrian

Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn

1800 West Vega Boulevard Vega TX
￥10,951
￥12,267 total
Sep 12 - Sep 13
includes taxes & fees
8/10 Very Good! (412 reviews)
Route 66 Desert Rose Country Inn
Days Inn by Wyndham Vega TX

Days Inn by Wyndham Vega TX

1005 S Main St Vega TX
￥14,079
￥15,768 total
Sep 10 - Sep 11
includes taxes & fees
Days Inn by Wyndham Vega TX

Frequently asked questions

What's the best place for a stay in Adrian?
Located 13 mi (20.9 km) from the heart of Adrian, Route 66 Desert Rose Country Inn is a top choice for your stay based on our traveler data. Days Inn by Wyndham Vega TX is another good option for your stay in the area. See all available top hotels, or vacation rentals in Adrian.
What are some of the best vacation rentals that Adrian has to offer?
Route 66 Retreat: This vacation home rental outside of Adrian has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Adrian.
If I need to cancel my hotel reservation in Adrian, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Adrian.
Where can I learn more about changing or cancelling my trip to Adrian?
To find more details about picking new dates or cancelling your trip to Adrian, head over to our customer service page.
What's the best hotel for staying near Rick Husband Amarillo International Airport (AMA)?
Holiday Inn Amarillo East is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an indoor pool. It's located 3.1 mi (5 km) from Rick Husband Amarillo Intl. Airport. Other good choices near the airport include Fairfield Inn & Suites Amarillo Airport and La Quinta Inn & Suites by Wyndham Amarillo Airport.
What's it like to stay in Adrian?
Visitors can enjoy all that Adrian has to offer including the local tours, shopping, and museums. There are 3 hotels and other accommodations in the surrounding area. Find out more about Adrian.
What should I see while I'm in Adrian?
A favorite place to visit is Midway Point of Route 66. Additionally, you'll find Magnolia Gas Station in the area. Check out what more to see and do in Expedia's Adrian guide.
What's the seasonal weather like in Adrian?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and December with an average of 43°F. Average annual precipitation for Adrian is 16 inches.

Explore a world of travel with Expedia