Find 4 Star Hotels in Florida Keys from ¥45,793

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Our top choices for Florida Keys 4-star hotels

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.4 out of 10, Exceptional, (1,389 reviews)
"Clean rooms, nice staff, great beach area."
United States
Brittany
The price is ¥47,933
¥60,337 total
includes taxes & fees
Apr 19 - Apr 20
Reefhouse Resort & Marina

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
4.0 star property
Key Largo
8.6 out of 10, Excellent, (1,015 reviews)
"The resort was beautiful. We really enjoyed our time there."
United States
Jessica
The price is ¥61,652
¥78,196 total
includes taxes & fees
Apr 12 - Apr 13
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Amara Cay Resort

Amara Cay Resort
4.0 star property
Matecumbe
8.8 out of 10, Excellent, (1,262 reviews)
"Yes the pool was fabulous. The Ocean view was quite good for a room that was not ocean front."
United States
Joseph
The price is ¥42,585
¥59,584 total
includes taxes & fees
Apr 14 - Apr 15
Amara Cay Resort

Hawks Cay Resort

Hawks Cay Resort
4.0 star property
Marathon
8.0 out of 10, Very Good, (1,001 reviews)
"4.5 of 5 stars - very nice resort"
United States
Robert
The price is ¥53,239
¥71,098 total
includes taxes & fees
Apr 26 - Apr 27
Hawks Cay Resort

Islander Resort

Islander Resort
4.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,005 reviews)
"Wonderful stay. Staff, rooms, grounds, food were all excellent."
United States
Kim
The price is ¥45,008
¥61,412 total
includes taxes & fees
Apr 12 - Apr 13
Islander Resort

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,004 reviews)
"Overall wonderful resort and great location. "
United States
Kristie Howle
The price is ¥79,675
¥98,438 total
includes taxes & fees
Apr 12 - Apr 13
Playa Largo Resort & Spa, Autograph Collection

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
4.0 star property
Islamorada
9.0 out of 10, Wonderful, (179 reviews)
"Very, very good architectural design and construction. And a well-maintained facility."
United States
roy steven
The price is ¥62,296
¥80,681 total
includes taxes & fees
Apr 13 - Apr 14
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

La Siesta Resort & Villas

La Siesta Resort & Villas
4.0 star property
Matecumbe
8.6 out of 10, Excellent, (1,002 reviews)
"We had a enjoyable stay here and would come back again if we were ever in the area. "
United States
angela
The price is ¥30,326
¥45,793 total
includes taxes & fees
Apr 14 - Apr 15
La Siesta Resort & Villas

Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
4.0 star property
Marathon
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing resort "
United States
Joy
The price is ¥76,821
¥97,206 total
includes taxes & fees
Apr 22 - Apr 23
Tranquility Bay Beachfront Hotel and Resort

Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
4.0 star property
Marathon
8.2 out of 10, Very Good, (183 reviews)
"We had a great stay."
United States
Elise
Villas At Hawks Cay Resort

Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
4.0 star property
Marathon
9.4 out of 10, Exceptional, (421 reviews)
"Yes the view was nice, the hotel staff was nice and the room was clean"
United States
DEBORAH LEE
The price is ¥53,501
¥67,884 total
includes taxes & fees
Apr 26 - Apr 27
Grassy Flats Resort & Beach Club

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (73 reviews)
"This place exceeded my expectations. Such a beautiful and quiet setting. Don't want to leave, but I will definitely be backa a beautiful "
United States
Beth
The price is ¥111,609
¥134,362 total
includes taxes & fees
Apr 13 - Apr 14
The Islands of Islamorada

The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys
4.0 star property
Marathon
9.2 out of 10, Wonderful, (15 reviews)
"Absolutely LOVED this place!! Affordable rates first of all, clean! Arrived late for check in and it was a quick smooth process, friendly staff. Definitely going back! "
United States
Angie
The Reef at Marathon, Florida Keys

Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
4.0 star property
Marathon
10.0 out of 10, Exceptional, (2 reviews)
"Wonderful vacation!"
United States
Chardell
Marlin Bay Resort & Marina

Waterfront Luxury Villa

Waterfront Luxury Villa
4.0 star property
Marathon Shores
Waterfront Luxury Villa

The Caribbean Resort Coconut Palm North

The Caribbean Resort Coconut Palm North
4.0 star property
Matecumbe
The Caribbean Resort Coconut Palm North
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Explore similar 5-star hotels

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Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

Top Florida Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favorite in this city that offers a tennis court and a sauna. Another stay that rates highly with travelers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from ¥70,731

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveler experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodations generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.