I've had mixed luck on finding great Vrbo's but hit the jackpot with The Gallery. We've saved it as a favorite to revisit another time. The location is absolutely perfect if you want to stay in the Riverwalk district. It's basically on the corner of Front St and Market and close to everything you could need. With the noon checkout, we were able to have a leisurely morning before finding a spot for brunch (Dixie Grill is literally right out the door.)
If you don't like a TV in the bedroom, this would be great for you. But, there is a little bit of ambient noise from the streets; you are right at the center of all the bars and clubs, but it wasn't bad at all. We were actually pretty surprised at how quiet it was overall.
If you don't/can't do stairs - this is not the place for you. Likewise, it is not an ideal spot for children. We didn't use the kitchen, other than the fridge, but it seemed fully equipped if you were going to stay long enough to want to make some meals.
Perfect for a couple, maybe even a trio of friends.
We will be back!