Lodging Image

Find hotels in Uptown, Collinsville

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Jul 17 - Jul 19
In two weeks
Jul 24 - Jul 26

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Uptown hotels

Lobby

Comfort Inn Alton near I-255

Comfort Inn Alton near I-255
2.5 star property
29.1 km from Uptown
7.4 out of 10, Good, (580 reviews)
"Beautiful area!!"
United States
Krystyne
The price is ￥14,406
￥16,420 total
includes taxes & fees
Jul 26 - Jul 27
Comfort Inn Alton near I-255
Breakfast, dinner and brunch served

The Principal Hotel

The Principal Hotel
3.5 star property
30.7 km from Uptown
9.6 out of 10, Exceptional, (337 reviews)
"Great hotel and nice staff!"
United States
Michelle
The price is ￥17,455
￥19,371 total
includes taxes & fees
Jul 13 - Jul 14
The Principal Hotel
Deluxe Studio Suite, 1 King Bed, Non Smoking | Pillowtop beds, in-room safe, desk, laptop workspace

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon
2.0 star property
14.1 km from Uptown
6.6 out of 10, (1,041 reviews)
"Very solid value for the money spent. Most super 8 hotels I have stayed in were sketchy. My room at this super 8 was clean and smelled nice, the breakfast was good, and the pool area was well-kept. Would go back if my flight gets canceled again."
United States
Lucas
The price is ￥8,108
￥9,323 total
includes taxes & fees
Jul 19 - Jul 20
Super 8 by Wyndham O'Fallon
Exterior

Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
20.9 km from Uptown
8.0 out of 10, Very Good, (348 reviews)
"It was really clean. Stuff was great. "
United States
Mark
The price is ￥17,124
￥20,022 total
includes taxes & fees
Aug 9 - Aug 10
Comfort Inn & Suites Saint Louis Lafayette Square
Suite, 1 King Bed, Non Smoking (One-Bedroom, Honeymoon) | Jetted tub

Seasons Inn & Suites Highland

Seasons Inn & Suites Highland
2.5 star property
28.5 km from Uptown
8.0 out of 10, Very Good, (668 reviews)
"The staff is very friendly and accommodating they took care of us very well. "
United States
Philip
The price is ￥17,694
￥19,636 total
includes taxes & fees
Jul 13 - Jul 14
Seasons Inn & Suites Highland
5 restaurants; breakfast, lunch, dinner, and brunch served

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
28.2 km from Uptown
9.2 out of 10, Wonderful, (1,662 reviews)
"Friendly staff and clean room, great value"
United States
Christian
The price is ￥15,365
￥20,235 total
includes taxes & fees
Aug 3 - Aug 4
River City Casino & Hotel
Exterior

Bel Air Motel

Bel Air Motel
3.5 star property
23.6 km from Uptown
8.6 out of 10, Excellent, (224 reviews)
"Clean rooms, good stay"
United States
Tai
The price is ￥12,369
￥15,182 total
includes taxes & fees
Jul 13 - Jul 14
Bel Air Motel
Gazebo

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
13.6 km from Uptown
8.6 out of 10, Excellent, (720 reviews)
"We had a great stay and the breakfast was really good."
United States
Tonya
The price is ￥16,006
￥18,404 total
includes taxes & fees
Aug 2 - Aug 3
Country Hearth Inn & Suites Edwardsville St. Louis
Free daily buffet breakfast

Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
19.9 km from Uptown
9.0 out of 10, Wonderful, (1,004 reviews)
"Great stay. Clean facility and professional staff"
United States
Ira
The price is ￥18,423
￥20,998 total
includes taxes & fees
Jul 19 - Jul 20
Best Western Plus MidAmerica Hotel
Indoor pool

Best Western Troy Hotel

Best Western Troy Hotel
2.5 star property
10.1 km from Uptown
8.0 out of 10, Very Good, (1,007 reviews)
"We stayed at the best western in May 2026. The room was very clean, staff was helpful, we had all that we needed. The breakfast was also great. We would definitely stay here again."
United States
Joyce
The price is ￥12,805
￥14,211 total
includes taxes & fees
Jul 13 - Jul 14
Best Western Troy Hotel
Room, 1 Queen Bed, Jetted Tub | Blackout drapes, free WiFi, bed sheets

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
12.3 km from Uptown
7.8 out of 10, Good, (690 reviews)
"GREAT PLACE GREAT HELPFUL STAFF ASWELL"
United States
maurice
The price is ￥10,833
￥12,264 total
includes taxes & fees
Aug 7 - Aug 8
Red Lion Inn & Suites Pontoon Beach
Lobby

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
10.9 km from Uptown
8.4 out of 10, Very Good, (887 reviews)
"Enjoyed my stay! Hotel was nice and convenient"
United States
Renita M.
The price is ￥14,228
￥16,359 total
includes taxes & fees
Aug 10 - Aug 11
Comfort Inn Edwardsville - St. Louis
Indoor pool

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
9.9 km from Uptown
8.0 out of 10, Very Good, (1,007 reviews)
"Good customer service well put together hotel"
United States
Donta
The price is ￥11,681
￥12,964 total
includes taxes & fees
Jul 19 - Jul 20
Super 8 by Wyndham Troy IL/St. Louis Area
Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, laptop workspace, blackout drapes

Comfort Inn & Suites O'Fallon - St. Louis Area

Comfort Inn & Suites O'Fallon - St. Louis Area
2.0 star property
9.6 km from Uptown
6.4 out of 10, (162 reviews)
"Convenient location "
United States
Peter
The price is ￥12,134
￥13,952 total
includes taxes & fees
Jul 15 - Jul 16
Comfort Inn & Suites O'Fallon - St. Louis Area
Free daily buffet breakfast

Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights
2.5 star property
7.3 km from Uptown
7.8 out of 10, Good, (33 reviews)
"The room was clean well kept and a good location!!"
United States
Landra
The price is ￥12,920
￥14,598 total
includes taxes & fees
Jul 19 - Jul 20
Best Western St. Louis Fairview Heights
Reception

Motel 6 Troy, IL

Motel 6 Troy, IL
2.0 star property
9.8 km from Uptown
7.6 out of 10, Good, (550 reviews)
"Rooms are dirty tovels pillow all dirty but staff is helpful room big but dirty"
United States
Baturalp
The price is ￥11,316
￥12,559 total
includes taxes & fees
Jul 13 - Jul 14
Motel 6 Troy, IL
Free daily continental breakfast

Days Inn by Wyndham Troy IL

Days Inn by Wyndham Troy IL
2.0 star property
9.7 km from Uptown
7.8 out of 10, Good, (329 reviews)
"Unfortunately we had to move rooms because there were multiple roaches when we went in. The room we were moved to appeared to have not been used in a while so it was hot when we walked in. We also had to kill two brown recluses (one on the floor under air conditioner and one in the sink). There were spider webs in the corners and dead bugs on the floor. I would not stay here again."
United States
Cameron
The price is ￥12,094
￥13,422 total
includes taxes & fees
Jul 14 - Jul 15
Days Inn by Wyndham Troy IL
Bar (on property)

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
17.9 km from Uptown
8.8 out of 10, Excellent, (1,334 reviews)
"Great location, walkable, dog friendly. Beautiful room, comfy bed, excellent value for cost."
United States
kristin Elizabeth
The price is ￥22,474
￥26,728 total
includes taxes & fees
Jul 13 - Jul 14
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Standard King Room with Whirlpool - Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn O'Fallon IL - St. Louis

Quality Inn O'Fallon IL - St. Louis
3.0 star property
9 km from Uptown
7.4 out of 10, Good, (1,009 reviews)
"Great place to stay"
United States
Tammy
The price is ￥11,473
￥13,192 total
includes taxes & fees
Jul 15 - Jul 16
Quality Inn O'Fallon IL - St. Louis
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
17.8 km from Uptown
9.6 out of 10, Exceptional, (3,579 reviews)
"Wonderful place to stay in St Louis! Great location, great staff, wonderful breakfast buffet, and reasonably priced!"
United States
Christopher
The price is ￥27,484
￥32,136 total
includes taxes & fees
Jul 14 - Jul 15
Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most.
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.

Mulberry Hills

While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

A large, historic building with arched windows and a prominent corner entrance.

Historic Downtown Collinsville

While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.

Top Uptown Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

8/10 Good
"Great property! Clean and convenient for a Cardinals game. A word of advice: If you are staying here and going the game, arrive EARLY! The valet parking is grid-lock. You could be sitting in traffic for up to an hour before your car gets parked."
John 1-night trip
Posted less than an hour ago
Hyatt Regency St. Louis at The Arch

Frequently asked questions

What is Uptown like?
Travelers to the Uptown neighborhood in Collinsville will be sure to enjoy their stay. Are you looking for Uptown travel tips? Be sure to check out World's Largest Catsup Bottle and Kruta Bakery while you're in the neighborhood.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer in Uptown.
Where can I learn more about changing or cancelling my trip to Uptown?
For additional details about picking new dates or cancelling your trip to Uptown, click here.
What is there to do in this Collinsville neighborhood?
A few attractions you might want to check out while you're in Uptown are World's Largest Catsup Bottle and Kruta Bakery. While you're out sightseeing, Gateway Conference Center and Gateway Fun Park are a couple of additional sights to visit in Collinsville.