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Nov 6 - Nov 8
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Our top choices for Substance hotels

A rooftop lounge with a fire pit, large windows, and a city view.

1. Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
Downtown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,774 reviews)
"Great place to stay"
United States
Cesar
The price is ￥18,789
￥30,153 total
includes taxes & fees
Nov 11 - Nov 12
Circa Resort & Casino – Adults Only
A spacious dining area with wooden tables and chairs, ornate ceiling design, and a central decorative piece.

2. Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery
2.5 star property
Downtown Las Vegas, 0.6 km from Substance
9.0 out of 10, Wonderful, (3,935 reviews)
"Great place to stay!!!"
United States
Michelle
The price is ￥4,310
￥10,757 total
includes taxes & fees
Nov 18 - Nov 19
Main Street Station Hotel, Casino and Brewery
A storefront with a glass door, a black awning, and a floral archway.

3. The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
Arts District, 1.4 km from Substance
9.2 out of 10, Wonderful, (159 reviews)
"Great stay"
United States
Enrico
The price is ￥25,420
￥28,724 total
includes taxes & fees
Nov 22 - Nov 23
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
A bar area with a leather couch, red chairs, and a bar counter.

4. Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.6 out of 10, Excellent, (9,895 reviews)
"Friendly staff, great location, easy parking."
United States
Amy
The price is ￥6,577
￥14,389 total
includes taxes & fees
Nov 16 - Nov 17
Downtown Grand Las Vegas
A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

5. Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,474 reviews)
"Always a nice place to stay"
United States
jose
The price is ￥8,655
￥9,780 total
includes taxes & fees
Nov 10 - Nov 11
Four Queens Hotel and Casino
An outdoor seating area with a wooden bench, a table with food, potted plants, and a view of the building's interior through a glass door.

6. AC Hotel by Marriott Las Vegas Symphony Park

AC Hotel by Marriott Las Vegas Symphony Park
2.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (295 reviews)
"Great stay. Only thing that wasnt great was bar and restaurant service. Bar staff was very rude and made us feel like we were a hindrance."
United States
Alison
The price is ￥19,653
￥26,170 total
includes taxes & fees
Nov 8 - Nov 9
AC Hotel by Marriott Las Vegas Symphony Park
A modern reception desk with vertical light fixtures and a marble counter.

7. Element by Marriott Las Vegas Symphony Park

Element by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (160 reviews)
"Spotless, brand-new feel in a quiet location ​Fantastic hotel! It was clean, quiet, and still smelled brand new. Staying in Symphony Park provided a relaxing break from the busy Strip while keeping us close to our festival venue. Modern, great facilities, and a wonderful overall stay."
United States
Suzanne
The price is ￥21,157
￥27,854 total
includes taxes & fees
Nov 23 - Nov 24
Element by Marriott Las Vegas Symphony Park
A brick-walled interior with a wooden floor and a black metal railing.

8. the D Las Vegas

the D Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.6 out of 10, Excellent, (7,741 reviews)
"Nice place to stay."
United States
Dave
The price is ￥4,579
￥12,301 total
includes taxes & fees
Nov 22 - Nov 23
the D Las Vegas
A spacious lobby with a stone floor, wooden beams, and a large chandelier.

9. El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over
3.0 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (7,072 reviews)
"I loved our stay. The rooms were cute and conveniently across the casino!"
United States
Evelia
The price is ￥6,235
￥12,397 total
includes taxes & fees
Nov 25 - Nov 26
El Cortez Hotel and Casino - 21 and Over
A large, modern steakhouse with a curved roof and multiple dining areas, surrounded by other buildings.

10. Plaza Hotel & Casino

Plaza Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.6 km from Substance
8.4 out of 10, Very good, (5,706 reviews)
"The location is great free parking and breakfast options"
United States
saul
The price is ￥4,724
￥12,296 total
includes taxes & fees
Nov 9 - Nov 10
Plaza Hotel & Casino
A restaurant with a view of a neon-lit building and a large screen displaying an image of a person.

11. Hotel Apache

Hotel Apache
3.5 star property
Downtown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very good, (1,169 reviews)
"Always a nice place to stay"
United States
jose
The price is ￥7,385
￥8,345 total
includes taxes & fees
Nov 12 - Nov 13
Hotel Apache
A hotel with a prominent sign reading "California Hotel & Casino."

12. California Hotel and Casino

California Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.5 km from Substance
8.8 out of 10, Excellent, (1,476 reviews)
"Friendly staff and clean rooms"
United States
Zoe
The price is ￥5,029
￥11,568 total
includes taxes & fees
Nov 24 - Nov 25
California Hotel and Casino
A bedroom with a bed, a small table, and a chair. There is a bathroom with a sink, mirror, and shower.

13. Desert Moon Motel

Desert Moon Motel
2.5 star property
Downtown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very good, (523 reviews)
"A great value for an extremely nice and clean hotel room. Great staff and location too !"
United States
Grant
The price is ￥8,187
￥9,251 total
includes taxes & fees
Nov 15 - Nov 16
Desert Moon Motel
A hotel with a large indoor pool, palm trees, and a modern building in the background.

14. Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very good, (14,866 reviews)
"Wonderful stay, clean rooms, comfy beds, large bathrooms, and lovely restaurants!"
United States
Andrea
The price is ￥5,589
￥14,523 total
includes taxes & fees
Nov 9 - Nov 10
Golden Nugget Las Vegas Hotel & Casino
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and tall buildings.

15. Oasis at Gold Spike

Oasis at Gold Spike
3.5 star property
Downtown Las Vegas, < 0.1 km from Substance
8.2 out of 10, Very good, (2,344 reviews)
"Great hotel"
United States
Zachary
The price is ￥7,323
￥12,752 total
includes taxes & fees
Nov 8 - Nov 9
Oasis at Gold Spike
A hotel room with two beds, a desk, a chair, a large mirror, and a decorative wall with geometric patterns.

16. Downtowner Boutique Hotel

Downtowner Boutique Hotel
3.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.0 out of 10, Very good, (186 reviews)
"Cute clean hotel, located just off the hustle and bustle of Fremont street."
United States
Nicholas
The price is ￥5,209
￥9,454 total
includes taxes & fees
Nov 12 - Nov 13
Downtowner Boutique Hotel
A nighttime view of a pool area with a city skyline in the background, including a prominent tower.

17. Bposhtels Las Vegas

Bposhtels Las Vegas
2.5 star property
1.8 km from Substance
7.8 out of 10, Good, (353 reviews)
"The manager was very kind The house keeping was great and polite I. Would love to stay again but now have a local id Thanks Nichole"
United States
Nichole
The price is ￥3,631
￥5,887 total
includes taxes & fees
Nov 5 - Nov 6
Bposhtels Las Vegas
A hotel with a prominent tower and the name "STRAT" illuminated on the facade.

18. The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower
4.0 star property
Las Vegas Strip, 2.9 km from Substance
7.6 out of 10, Good, (25,998 reviews)
"I love staying here when I visit!"
United States
Steve
The price is ￥1,874
￥11,066 total
includes taxes & fees
Nov 16 - Nov 17
The STRAT Hotel, Casino & Tower
The exterior of the Golden Gate Hotel with a prominent sign, a modern architectural design, and a parking lot with visible cars.

19. Golden Gate Hotel and Casino

Golden Gate Hotel and Casino
2.5 star property
Downtown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,171 reviews)
"Great place to stay"
United States
Christian
The price is ￥3,789
￥11,409 total
includes taxes & fees
Nov 11 - Nov 12
Golden Gate Hotel and Casino
A hotel room with a large bed, a bedside table, a chair, a desk, and a mirror.

20. Crown Motel

Crown Motel
2.5 star property
Sunrise Manor, 3.1 km from Substance
7.4 out of 10, Good, (80 reviews)
"Decent hotel"
United States
Jeff
The price is ￥21,173
￥25,504 total
includes taxes & fees
Nov 5 - Nov 6
Crown Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Substance

A rooftop lounge with a fire pit, large windows, and a city view.

Circa Resort & Casino – Adults Only

4.5 star property
Downtown Las Vegas, 0.5 km from Substance
View
A spacious dining area with wooden tables and chairs, ornate ceiling design, and a central decorative piece.

Main Street Station Hotel, Casino and Brewery

2.5 star property
Downtown Las Vegas, 0.6 km from Substance
View
A storefront with a glass door, a black awning, and a floral archway.

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

4.0 star property
Arts District, 1.4 km from Substance
View
A bar area with a leather couch, red chairs, and a bar counter.

Downtown Grand Las Vegas

3.5 star property
Downtown Las Vegas, 0.2 km from Substance
View
A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

Four Queens Hotel and Casino

3.5 star property
Downtown Las Vegas, 0.3 km from Substance
View
9.4
Exceptional
5,774 reviews
9.0
Wonderful
3,935 reviews
9.2
Wonderful
159 reviews
8.6
Excellent
9,895 reviews
8.6
Excellent
7,474 reviews
The price is ￥18,789
￥30,153 total
includes taxes & fees
Nov 11 - Nov 12
The price is ￥4,310
￥10,757 total
includes taxes & fees
Nov 18 - Nov 19
The price is ￥25,420
￥28,724 total
includes taxes & fees
Nov 22 - Nov 23
The price is ￥6,577
￥14,389 total
includes taxes & fees
Nov 16 - Nov 17
The price is ￥8,655
￥9,780 total
includes taxes & fees
Nov 10 - Nov 11
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • No WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families near Substance

A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas
8.6 out of 10, Excellent, (7,474)
The price is ￥8,655
￥9,780 total
includes taxes & fees
Nov 10 - Nov 11
Four Queens Hotel and Casino

Top Substance Hotel Reviews

The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower

8/10 Good
"A good clean hotel with really good staff; food choices are expensive, even Starbucks charges $1.35 for a glass of water, free everywhere else."
Azhar 2-night trip
Posted 1 hour ago
The STRAT Hotel, Casino & Tower

Other attractions near Substance

The exterior of the Neonopolis building with the Telemundo Las Vegas sign above.

Neonopolis

You can spend time studying the exhibits at Neonopolis during your travels in Las Vegas. Discover the entertainment choices and casinos in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Substance?
Substance is located in Las Vegas. This welcoming area is known for its array of dining options and bar scene. If you're looking for a convenient place to stay, check out the 156 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Substance?
Adjacent to Substance, Golden Nugget Las Vegas Hotel & Casino is one of the top choices for your stay based on our traveler data, and this resort offers 2 outdoor pools and a full-service spa. Other good options within a short distance include Plaza Hotel & Casino and Downtown Grand Las Vegas.
How many hotels are there close to Substance?
Expedia has 156 hotels and other accommodations within a mile from Substance.
If I need to cancel the hotel reservation for my stay near Substance, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review top deals close to Substance.
Where can I learn more about changing or cancelling my trip in the area near Substance?
For more details about rescheduling or cancelling your stay near Substance, click here.
What can I see and do near Substance?
You might want to spend some time browsing the exhibits at Mob Museum, The Neon Museum, or Zak Bagans Haunted Museum. Old Las Vegas Mormon Fort State Historic Park, Harrison House, and First AME Church are monuments to see when you're exploring the area around Substance. You can watch performances at Colosseum at Caesars Palace, Sphere, and Dolby Live if you're interested in local theater.