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Check prices for these dates

Next weekend
Jun 19 - Jun 21
In two weeks
Jun 26 - Jun 28

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Our top choices for Substance hotels

Exterior

Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
Downtown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,666 reviews)
"Great place!"
United States
Victor Hugo
The price is ￥19,069
￥30,602 total
includes taxes & fees
Jun 16 - Jun 17
Circa Resort & Casino – Adults Only
Exterior

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
Arts District, 1.4 km from Substance
9.4 out of 10, Exceptional, (129 reviews)
"Excellent property "
United States
Leroy
The price is ￥18,588
￥21,004 total
includes taxes & fees
Jun 21 - Jun 22
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
Daily buffet breakfast for a fee

Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery
2.5 star property
Downtown Las Vegas, 0.6 km from Substance
9.0 out of 10, Wonderful, (3,365 reviews)
"Nice people, clean rooms, great food, buffet is the best! would absolutely stay here again."
United States
Nathan J
The price is ￥3,927
￥10,411 total
includes taxes & fees
Jun 28 - Jun 29
Main Street Station Hotel, Casino and Brewery
View from property

Element by Marriott Las Vegas Symphony Park

Element by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
9.2 out of 10, Wonderful, (110 reviews)
"very clean room, easy access, good breakfast, good parking"
United States
Joanna
The price is ￥17,842
￥24,167 total
includes taxes & fees
Jun 30 - Jul 1
Element by Marriott Las Vegas Symphony Park
In-room safe, blackout drapes, iron/ironing board, free WiFi

Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,170 reviews)
"Great stay"
United States
Ronald
The price is ￥8,899
￥10,055 total
includes taxes & fees
Jun 23 - Jun 24
Four Queens Hotel and Casino
Property entrance

El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over
3.0 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very Good, (7,255 reviews)
"Always a great stay"
United States
Sharon
The price is ￥6,124
￥12,352 total
includes taxes & fees
Jul 14 - Jul 15
El Cortez Hotel and Casino - 21 and Over
Coffee shop

Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very Good, (10,034 reviews)
"Great absolutely would stay there again"
United States
Michael
The price is ￥5,624
￥13,417 total
includes taxes & fees
Jun 22 - Jun 23
Downtown Grand Las Vegas
3 restaurants; breakfast, lunch, and dinner served

the D Las Vegas

the D Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very Good, (7,509 reviews)
"Great breakfast deal at their restaurant"
United States
Bertha
The price is ￥4,368
￥12,170 total
includes taxes & fees
Jun 25 - Jun 26
the D Las Vegas
4 bars/lounges

Hotel Apache

Hotel Apache
3.5 star property
Downtown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very Good, (1,139 reviews)
"front desk was amazing and casino had great drink service"
Canada
Darren
The price is ￥6,176
￥6,979 total
includes taxes & fees
Jul 9 - Jul 10
Hotel Apache
Terrace/patio

AC Hotel by Marriott Las Vegas Symphony Park

AC Hotel by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (218 reviews)
"Beautiful hotel, great location! Would definitely stay here again."
United States
Luis Alberto
The price is ￥16,344
￥22,475 total
includes taxes & fees
Jul 5 - Jul 6
AC Hotel by Marriott Las Vegas Symphony Park
2 outdoor pools, cabanas (surcharge), sun loungers

Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very Good, (13,526 reviews)
"Our stay was fantastic!"
United States
Cheyenne
The price is ￥5,304
￥14,323 total
includes taxes & fees
Jun 17 - Jun 18
Golden Nugget Las Vegas Hotel & Casino
Dinner served

Plaza Hotel & Casino

Plaza Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.6 km from Substance
8.2 out of 10, Very Good, (5,290 reviews)
"Had a great time it’s a wonderful place to stay"
United States
Susan
The price is ￥4,903
￥12,603 total
includes taxes & fees
Jun 15 - Jun 16
Plaza Hotel & Casino
4 bars/lounges

Fremont Hotel & Casino

Fremont Hotel & Casino
3.0 star property
Downtown Las Vegas, 0.3 km from Substance
8.8 out of 10, Excellent, (4,353 reviews)
"Great place to stay."
United States
John
The price is ￥4,110
￥10,800 total
includes taxes & fees
Jun 29 - Jun 30
Fremont Hotel & Casino
Courtyard

Oasis at Gold Spike

Oasis at Gold Spike
3.5 star property
Downtown Las Vegas, < 0.1 km from Substance
8.0 out of 10, Very Good, (2,281 reviews)
"Very cozy and fun place to stay! "
United States
Alexis
The price is ￥5,624
￥9,977 total
includes taxes & fees
Jun 15 - Jun 16
Oasis at Gold Spike
Double-King Suite with Kitchen | Bathroom

Desert Moon Motel

Desert Moon Motel
2.5 star property
Downtown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very Good, (499 reviews)
"It may not seem like much from the outside but the rooms are really nice with a lot of amenities. Clean and comfy beds and a nice tv."
United States
maricsa
The price is ￥7,786
￥8,798 total
includes taxes & fees
Jul 14 - Jul 15
Desert Moon Motel
Fairway Double Queen | Premium bedding, iron/ironing board, bed sheets, wheelchair access

Downtowner Boutique Hotel

Downtowner Boutique Hotel
3.0 star property
Downtown Las Vegas, 0.4 km from Substance
7.6 out of 10, Good, (42 reviews)
"Great AC, clean rooms, knowledgeable staff, very close to Freemont street perfect for a fun weekend."
United States
Vivianna
The price is ￥4,903
￥9,161 total
includes taxes & fees
Jun 15 - Jun 16
Downtowner Boutique Hotel
Front of property - evening/night

Golden Gate Hotel and Casino

Golden Gate Hotel and Casino
2.5 star property
Downtown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,069 reviews)
"Fun stay"
United States
Thomas
The price is ￥3,846
￥11,579 total
includes taxes & fees
Jun 15 - Jun 16
Golden Gate Hotel and Casino
Combined shower/tub, free toiletries, hair dryer, towels

Bposhtels Las Vegas

Bposhtels Las Vegas
2.5 star property
1.8 km from Substance
7.6 out of 10, Good, (293 reviews)
"Clean and safe. Would definitely stay there again."
United States
Hugo
The price is ￥4,230
￥6,590 total
includes taxes & fees
Jun 16 - Jun 17
Bposhtels Las Vegas
Exterior

The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower
4.0 star property
Las Vegas Strip, 2.9 km from Substance
7.6 out of 10, Good, (23,536 reviews)
"Great place to stay!"
United States
Ronald
The price is ￥1,514
￥10,791 total
includes taxes & fees
Jun 23 - Jun 24
The STRAT Hotel, Casino & Tower
Front of property

Thunderbird Hotel

Thunderbird Hotel
2.5 star property
Gateway District, 1.8 km from Substance
7.2 out of 10, Good, (1,003 reviews)
"Clean and spacious and quiet room easy parking"
United States
Chandramouli
The price is ￥6,490
￥10,412 total
includes taxes & fees
Jun 15 - Jun 16
Thunderbird Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Substance

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Exterior
Circa Resort & Casino – Adults Only
4.5 star property
9.4
Exceptional
5,666 reviews
View
Exterior
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
9.4
Exceptional
129 reviews
View
Daily buffet breakfast for a fee
Main Street Station Hotel, Casino and Brewery
2.5 star property
9.0
Wonderful
3,365 reviews
View
View from property
Element by Marriott Las Vegas Symphony Park
3.0 star property
9.2
Wonderful
110 reviews
View
In-room safe, blackout drapes, iron/ironing board, free WiFi
Four Queens Hotel and Casino
3.5 star property
8.6
Excellent
7,170 reviews
View

Top Substance Hotel Reviews

Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino

10/10 Excellent
"Friendly staff and helpful."
Anna 2-night trip
Posted less than an hour ago
Golden Nugget Las Vegas Hotel & Casino

Hotels near other Substance attractions

www.alamy.com

Neonopolis

You can spend time studying the exhibits at Neonopolis during your travels in Las Vegas. Discover the entertainment choices and casinos in this family-friendly area.
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Frequently asked questions

What's the area like around Substance?
Substance is located in Las Vegas. This welcoming area is known for its array of dining options and bar scene. If you're looking for a convenient place to stay, check out the 174 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Substance?
Adjacent to Substance, Golden Nugget Las Vegas Hotel & Casino is one of the top choices for your stay based on our traveler data, and this resort offers 2 outdoor pools and a full-service spa. Other good options within a short distance include Downtown Grand Las Vegas and Fremont Hotel & Casino.
How many hotels are there close to Substance?
Expedia has 174 hotels and other accommodations within a mile from Substance.
If I need to cancel the hotel reservation for my stay near Substance, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to review top deals close to Substance.
Where can I learn more about changing or cancelling my trip in the area near Substance?
For more details about rescheduling or cancelling your stay near Substance, click here.
What can I see and do near Substance?
You might want to spend some time browsing the exhibits at Mob Museum, The Neon Museum, or Zak Bagans Haunted Museum. Old Las Vegas Mormon Fort State Historic Park, Harrison House, and First AME Church are monuments to see when you're exploring the area around Substance. You can watch performances at Colosseum at Caesars Palace, Sphere, and Dolby Live if you're interested in local theater.