A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Resorts & Hotels with Spas

Tonight
Oct 19 - Oct 20
Tomorrow
Oct 20 - Oct 21
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Southern Indiana hotels with a spa

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern interior with a fireplace, bookshelves, and seating areas.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

1. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
￥32,110
￥37,780 total
includes taxes & fees
Nov 16 - Nov 17
Omni Louisville Hotel
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A balcony with a view of a river, a bridge, and a cityscape.

2. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
￥22,156
￥26,070 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
A restaurant with round tables, chairs, chandeliers, and a bar area.
A spacious lobby with a geometric chandelier, a reception desk, and a red accent wall.
A large hotel with a prominent 'Caesars' sign, multiple floors, and a symmetrical facade.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.

3. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
￥9,563
￥13,774 total
includes taxes & fees
Nov 17 - Nov 18
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A treatment room with a massage table, a desk with a computer, and a large mirror.
A luxurious bathroom with a large mirror, a bathtub, and a shower area.
A golf course with a flag, a sand bunker, and a building in the background.
A poolside area with lounge chairs and a towel with a monogram.

4. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
￥17,625
￥21,685 total
includes taxes & fees
Nov 19 - Nov 20
Belterra Casino Resort
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A steam fountain in a brick alleyway.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

5. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville.
￥24,043
￥29,079 total
includes taxes & fees
Nov 9 - Nov 10
21c Museum Hotel Louisville
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.
A spacious indoor area with a staircase, a vending machine, and a business center sign.
An indoor swimming pool with clear water, surrounded by lounge chairs and a small seating area.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center.
￥12,759
￥14,290 total
includes taxes & fees
Nov 17 - Nov 18
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A living room with a sofa, coffee table, and a television mounted on the wall.
A modern bathroom with a shower, a vanity with a sink, and a toilet. There are wooden shelves and a vase with flowers on the vanity.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
￥52,653
￥58,044 total
includes taxes & fees
Oct 27 - Oct 28
Pillow and Paddock B&B
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Choose what matters most at spa hotels in Southern Indiana

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Indiana Hotel Reviews

Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

10/10 Excellent
"Clean room, staff were great"
Benjamin 1-night trip
Posted 16 hours ago
Drury Inn & Suites Evansville East
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

8/10 Good
"Bed was clean and very comfortable. The toilet sat very low however, the bathroom was very clean. Breakfast bar was extremely good and well maintained and frequently stocked by the employees. Would recommend this facility."
Gary 1-night trip
Posted 1 day ago
Hampton Inn New Albany Louisville West
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent
"remodeled recently. very clean. nice. comfy bed..at least for us. quiet.. but we were at end of the hall. room had plenty of space. nice long bathroom counter for toiletries etc. that was outside of tub and potty area. plenty of choices for breakfast. employees friendly. would definitely stay again!!"
Marilyn 1-night trip
Posted 5 days ago
Ramada by Wyndham Sellersburg/Louisville North

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