A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Resorts & Hotels with Spas

Tonight
Sep 3 - Sep 4
Tomorrow
Sep 4 - Sep 5
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Southern Indiana hotels with a spa

A treatment room with a massage table, a desk with a computer, and a large mirror.
A poolside area with lounge chairs and a towel with a monogram.
A golf course with a flag, a sand bunker, and a building in the background.
A luxurious bathroom with a large mirror, a bathtub, and a shower area.

1. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
￥21,317
￥25,830 total
includes taxes & fees
Sep 17 - Sep 18
Belterra Casino Resort
A restaurant with round tables, chairs, chandeliers, and a bar area.
A spacious lobby with a geometric chandelier, a reception desk, and a red accent wall.
A large hotel with a prominent 'Caesars' sign, multiple floors, and a symmetrical facade.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.

2. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
￥9,609
￥13,843 total
includes taxes & fees
Oct 4 - Oct 5
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.
A balcony with a view of a river, a bridge, and a cityscape.

3. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
￥25,294
￥29,760 total
includes taxes & fees
Sep 6 - Sep 7
Galt House Hotel Trademark Collection by Wyndham
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A modern bathroom with a shower, a sink, and a large mirror.
A steam fountain in a brick alleyway.

4. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville.
￥26,856
￥32,393 total
includes taxes & fees
Oct 4 - Oct 5
21c Museum Hotel Louisville
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern interior with a fireplace, bookshelves, and seating areas.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

5. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
￥31,629
￥37,215 total
includes taxes & fees
Sep 4 - Sep 5
Omni Louisville Hotel
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A living room with a sofa, coffee table, and a television mounted on the wall.
A modern bathroom with a shower, a vanity with a sink, and a toilet. There are wooden shelves and a vase with flowers on the vanity.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.

6. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
￥44,911
￥49,510 total
includes taxes & fees
Sep 15 - Sep 16
Pillow and Paddock B&B
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A hotel room with a bed, desk, chair, and a green accent wall.
An indoor swimming pool with clear water, surrounded by lounge chairs and a small seating area.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.

7. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center.
￥12,820
￥14,359 total
includes taxes & fees
Oct 4 - Oct 5
Quality Inn Seymour I-65
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Choose what matters most at spa hotels in Southern Indiana

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Indiana Hotel Reviews

Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

10/10 Excellent
"Staff was friendly"
Tim 1-night trip
Posted 3 days ago
Drury Inn & Suites Evansville East
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

10/10 Excellent
"It's a very Kool place everything was great food was good people were polite water park was Kool but be ready for a saltwater pool not a chlorine pool"
Tod 2-night trip
Posted 3 weeks ago
Big Splash Adventure Indoor Water Park & Resort

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