Find Resorts & Hotels with Spas in Southern Indiana

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Our top choices for Southern Indiana hotels with a spa

Belterra Casino Resort

Belterra Casino Resort
3.5 star property
Florence
8.6 out of 10, Excellent, (1004)
"Room was clean and the staff was good."
United States
Gary
The price is ¥18,638
¥22,817 total
includes taxes & fees
Dec 23 - Dec 24
Belterra Casino Resort

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3896)
"Great place to stay! "
United States
Rochelle
The price is ¥21,028
¥24,742 total
includes taxes & fees
Dec 27 - Dec 28
Galt House Hotel Trademark Collection by Wyndham

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination
3.5 star property
Elizabeth
8.2 out of 10, Very Good, (1001)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
The price is ¥14,041
¥18,739 total
includes taxes & fees
Dec 23 - Dec 24
Caesars Southern Indiana - A Caesars Rewards Destination

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1743)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is ¥26,376
¥31,034 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Omni Louisville Hotel

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1004)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is ¥21,927
¥26,590 total
includes taxes & fees
Jan 1 - Jan 2, 2026
21c Museum Hotel Louisville

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is ¥26,029
¥38,100 total
includes taxes & fees
Dec 28 - Dec 29
The Reserve on Main

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (56)
"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."
United States
John
The price is ¥19,464
¥22,592 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Central Park Bed & Breakfast

Quality Inn Seymour I-65

Quality Inn Seymour I-65
2.5 star property
Seymour
7.0 out of 10, Good, (563)
"Had a room on first floor close to breakfast and desk."
United States
Karlyn
The price is ¥12,737
¥14,266 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Quality Inn Seymour I-65

Pillow and Paddock B&B

Pillow and Paddock B&B
3.5 star property
La Grange
10.0 out of 10, Exceptional, (52)
"Great stay. Great hospitality"
United States
James
The price is ¥56,746
¥62,557 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Pillow and Paddock B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southern Indiana Hotel Reviews