A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Luxury Hotels

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Southern Indiana luxury hotels

1. The Grady

The Grady
Downtown Louisville
¥29,897
¥35,177 total
includes taxes & fees
Sep 4 - Sep 5
The Grady

2. The Brown Hotel

The Brown Hotel
Downtown Louisville
  • Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.
¥23,893
¥28,113 total
includes taxes & fees
Sep 4 - Sep 5
The Brown Hotel

3. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
¥31,890
¥37,520 total
includes taxes & fees
Sep 2 - Sep 3
Omni Louisville Hotel

4. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.
¥28,656
¥34,518 total
includes taxes & fees
Sep 3 - Sep 4
21c Museum Hotel Louisville

5. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
¥35,244
¥41,467 total
includes taxes & fees
Sep 13 - Sep 14
Hotel Distil, Autograph Collection

6. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
¥14,379
¥16,249 total
includes taxes & fees
Sep 2 - Sep 3
The Pepin Mansion Historic B&B

7. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
¥28,749
¥33,826 total
includes taxes & fees
Sep 6 - Sep 7
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

8. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Upscale riverside hotel features panoramic views, spa services, and gourmet dining in downtown Louisville.
¥24,963
¥29,372 total
includes taxes & fees
Sep 10 - Sep 11
Galt House Hotel Trademark Collection by Wyndham

9. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
¥27,079
¥31,860 total
includes taxes & fees
Sep 5 - Sep 6
Louisville Marriott Downtown

10. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
  • Historic elegance meets modern luxury downtown, with pillowtop beds, designer toiletries, and 24-hour service.
¥24,302
¥28,593 total
includes taxes & fees
Sep 6 - Sep 7
Seelbach Hilton Louisville Downtown
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Top Southern Indiana Hotel Reviews

Howard Johnson by Wyndham Evansville East

Howard Johnson by Wyndham Evansville East

10/10 Excellent
"very clean , staff was very friendly and helpful was little disappointed in breakfast but was ok"
Gary 2-night trip
Posted 5 hours ago
Howard Johnson by Wyndham Evansville East

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