The Best Resorts & Hotels with Spas in Southeastern United States from ￥13,711 in 2026

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Check availability on Southeastern United States Resorts & Hotels with Spas

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Our top choices for Southeastern United States hotels with a spa

A modern spa entrance with a wooden slat partition, a reception desk, and a sign reading 'SPA'.

A modern outdoor seating area with a blue sofa, black and wooden chairs, and a view of a mountainous landscape.

A restaurant with a long counter, multiple tables, and chairs, large windows with a mountain view.

A modern hotel with a curved driveway, a parking area, and a well-maintained garden.

1. Harrah's Cherokee Valley River Hotel & Casino – A Caesars Rewards Destination

Murphy

￥8,157

￥15,240 total

includes taxes & fees

Sep 30 - Oct 1

A massage therapy session in a room with a wooden door, teal walls, and framed artwork.

A corridor with glass doors leading to a room, stone walls, and wooden beams.

A spacious lobby with a large chandelier, leather armchairs, and a central seating area.

A restaurant with wooden ceiling, chandeliers, and large windows. Tables are set with wine glasses and plates.

2. Brownwood Hotel & Spa

Wildwood

Rejuvenate at this serene spa hotel with 10 treatment rooms, including couples options, plus an inviting outdoor pool.

￥15,431

￥16,511 total

includes taxes & fees

Sep 16 - Sep 17

A hotel room with three beds, a small round table, and a large potted orchid.

An outdoor dining area with tables set for a meal, surrounded by arches and potted plants.

A spacious living room with a fireplace, large windows, and modern furniture.

A golf course with a pond, surrounded by lush greenery and trees.

3. Mission Resort and Club

Howey-in-the-Hills

Rejuvenate at this upscale lakeside retreat featuring a full-service spa with aromatherapy treatments and outdoor tennis courts.

￥13,748

￥20,401 total

includes taxes & fees

Sep 18 - Sep 19

A boutique hotel interior with a view of the beach, a mannequin, and various items on display.

A large swimming pool with multiple lanes, surrounded by palm trees and lounge chairs, with a hotel building in the background.

A large resort with a central pool, multiple buildings, and a pier extending into the water.

4. Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Punta Gorda

Rejuvenate at this waterfront spa resort with 10 treatment rooms and two outdoor pools for complete serenity.

￥15,116

￥24,710 total

includes taxes & fees

Oct 1 - Oct 2

A well-furnished living room with a sofa, armchairs, a coffee table, and a large abstract painting on the wall.

A spa room with reclining chairs, large windows, and a view of a pool area.

A large indoor swimming pool with blue lounge chairs and umbrellas, surrounded by palm trees and a high-rise building.

A high-rise hotel with a prominent 'Beau Rivage' sign, surrounded by a well-lit urban area with a view of the ocean at sunset.

5. Beau Rivage

Downtown Biloxi

Revitalize at this waterfront resort with 14 treatment rooms and couples massage suites where deep soaking tubs complement spa journeys.

￥24,424

￥30,969 total

includes taxes & fees

Oct 13 - Oct 14

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

A balcony with a wooden table, two glasses of red wine, and a bottle of wine. The balcony overlooks a beach and a building with multiple balconies.

A hotel with multiple buildings, a pool area, and a beach.

A balcony with a view of the beach, a table with a bottle and glass, and two blue chairs.

6. Pink Shell Beach Resort and Marina

Fort Myers Beach

￥31,212

￥44,907 total

includes taxes & fees

Sep 28 - Sep 29

A spa room with two beds, a large mirror, and a view of palm trees.

A modern lobby with a curved reception desk, large hanging lamps, and a neon sign indicating the address.

A lobby with a central staircase, a chandelier, and a reception desk.

A high-rise hotel with a prominent 'IP' sign, surrounded by palm trees and a busy street with light trails.

7. IP Casino Resort Spa - Biloxi

Biloxi

Relax at this resort spa with 19 treatment rooms, sauna, and steam room for rejuvenating escape.

￥11,880

￥16,429 total

includes taxes & fees

Sep 27 - Sep 28

A spa area with a hot tub, candles, and towels.

A spacious hotel lobby with a central staircase, multiple seating areas, and large windows offering views of the outdoor area.

A large hotel with multiple floors, surrounded by a well-maintained golf course and a lake.

An aerial view of a resort with multiple swimming pools, landscaped gardens, and outdoor seating areas.

8. Rosen Shingle Creek

Orlando

Indulge in rejuvenating spa treatments and golf at this riverside retreat with 9 treatment rooms and 4 outdoor pools.

￥17,299

￥19,461 total

includes taxes & fees

Sep 19 - Sep 20

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Choose what matters most at spa hotels in Southeastern United States

Pool

Breakfast included

Hot tub

4 stars

5 stars

Spa hotels with pools in Southeastern United States

A circular bar area with multiple seating arrangements and a central DJ booth.

A modern hotel with a curved roof structure, large glass windows, and a well-lit entrance area.

A large indoor swimming pool with a high ceiling and large windows.

A spacious lobby with a central seating area, a large chandelier, and a Starbucks sign in the background.

Harrah's Cherokee Casino Resort - A Caesars Rewards Destination

Cherokee

￥8,198

￥15,315 total

includes taxes & fees

Sep 30 - Oct 1

A spacious lobby with a grand chandelier, modern seating, and a view of the outdoor area.

A spa entrance with a wooden facade, a sign indicating a sauna, and a patterned metal partition.

A resort pool area with a winding pool design, lounge chairs, and palm trees.

A pool area with a chandelier, a statue, and a view of the outside.

Kompose Boutique Resort at Theme Parks

Kissimmee

￥6,059

￥13,711 total

includes taxes & fees

Sep 29 - Sep 30

A water park with multiple water slides and inflatable tubes in a pool area surrounded by rocky terrain and greenery.

A wooden fence leading to a stone pathway, surrounded by lush greenery and trees.

A spacious lobby with a central fireplace, large windows, and a chandelier.

A cozy cabin interior with a stone fireplace, wooden furniture, and large windows offering a view of the outdoors.

RiverStone Condo Resort & Spa

Pigeon Forge

￥9,427

￥29,677 total

includes taxes & fees

Sep 13 - Sep 14

A bathroom with a bathtub, a window with a view of the sea, and a beige tiled wall.

A modern hotel lobby with a bar area, a staircase, and a decorative neon sign.

IP Casino Resort Spa - Biloxi

Biloxi

￥11,880

￥16,429 total

includes taxes & fees

Sep 27 - Sep 28

A pool area with lounge chairs and palm trees.

A beach with palm trees, a thatched-roof structure, and a building with a red roof.

A multi-story hotel with a red roof, a swimming pool, and a beach area.

A hotel room with a large bed, a seating area with a table and chairs, a flat-screen TV, and a balcony with a view of the sea.

Harborside at Charleston Harbor Resort and Marina

Mount Pleasant

￥13,027

￥22,047 total

includes taxes & fees

Sep 13 - Sep 14

A modern restaurant with wooden flooring, bar seating, and a high ceiling with exposed beams.

Mission Resort and Club

Howey-in-the-Hills

￥13,748

￥20,401 total

includes taxes & fees

Sep 18 - Sep 19

A balcony with a table set for two, featuring a bottle of champagne, glasses, and a plate of fruit.

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Punta Gorda

￥15,116

￥24,710 total

includes taxes & fees

Oct 1 - Oct 2

A modern spa interior with a prominent sign for 'pure THE PALACE SPA'.

A modern hotel with a large pool area, outdoor seating, and a covered pavilion.

A large, two-story building with a stone facade, a central entrance with steps, and a symmetrical design.

A casino with multiple gaming tables and chairs, a large chandelier, and slot machines in the background.

Palace Casino Resort

Biloxi

￥13,466

￥15,081 total

includes taxes & fees

Sep 14 - Sep 15

A hotel pool area with lounge chairs and a covered seating area, reflecting in the water.

A bar area with a circular bar, multiple seating arrangements, and a decorative ceiling.

Beau Rivage

Downtown Biloxi

￥24,424

￥30,969 total

includes taxes & fees

Oct 13 - Oct 14

A beachfront hotel with multiple buildings, a sandy beach, and a water body in the background.

Pink Shell Beach Resort and Marina

Fort Myers Beach

￥31,212

￥44,907 total

includes taxes & fees

Sep 28 - Sep 29

View all properties

Spa hotels with free breakfast in Southeastern United States

A sandy beach with footprints and the word "HOLIDAYS" written in the sand.

A historic building with two towers, arched windows, and a well-lit garden with palm trees.

A corridor with a tray containing a bottle and two glasses.

A swimming pool with lounge chairs and a covered seating area, surrounded by a building with balconies and palm trees.