Photo by Serendipity Trip

Find Boutique Hotels in Southeastern Indiana

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeastern Indiana Boutique Hotels

Our top choices for Southeastern Indiana boutique hotels

Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1146)
"I loved everything about this place"
United States
Steven
The Brown Hotel
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is ￥21,591
￥26,183 total
includes taxes & fees
Jan 1 - Jan 2, 2026
21c Museum Hotel Louisville
Free daily full breakfast
Market Street Inn

Market Street Inn

3.5 star property
Jeffersonville
9.8 out of 10, Exceptional, (120)
"I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice."
United States
Megan
The price is ￥28,862
￥32,615 total
includes taxes & fees
Dec 10 - Dec 11
Market Street Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeastern Indiana Hotel Reviews

Explore a world of travel with Expedia