The Best Hotels Closest to Six Mile Cypress Slough Preserve in Fort Myers for 2026

A wooden boardwalk through a dense forest with green foliage and a clear blue sky.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Six Mile Cypress Slough Preserve hotels

A reception area with a counter, a sign indicating free Wi-Fi, and a wall-mounted sign for Home Towne Studios.

A swimming pool with a tiled deck, lounge chairs, and a building with multiple windows.

A poolside area with lounge chairs, umbrellas, and a view of the surrounding landscape.

A swimming pool with a tiled deck, a building with multiple windows, and a cloudy sky.

1. HomeTowne Studios by Red Roof Fort Myers

3 km from Six Mile Cypress Slough Preserve

￥9,459

￥10,547 total

includes taxes & fees

Aug 31 - Sep 1

2. 2 Mi to Six Mile Preserve! Family Getaway w/ Pool

2.2 km from Six Mile Cypress Slough Preserve

￥25,005

￥75,677 total

includes taxes & fees

Sep 10 - Sep 11

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

A covered outdoor seating area with wooden beams, white lattice railings, and colorful cushions.

A hotel lobby with a reception desk, a seating area with a sofa and chairs, a kitchenette, and a 'Welcome to Hampton' sign.

A pool area with lounge chairs, a gazebo, and a blue umbrella.

3. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor, 3.6 km from Six Mile Cypress Slough Preserve

Denise

￥11,624

￥12,960 total

includes taxes & fees

Sep 5 - Sep 6

A Holiday Inn Express building with a modern design, featuring a flat facade and a covered entrance area.

A Holiday Inn Express & Suites hotel with a modern facade, multiple floors, and a covered entrance.

A clear swimming pool with a 3 FT depth marker and a no diving sign.

A hotel lobby with a reception desk, seating area, and a large window.

4. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor, 6.3 km from Six Mile Cypress Slough Preserve

Brandon

￥17,360

￥19,356 total

includes taxes & fees

Aug 29 - Aug 30

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

A hotel lobby with a brown sofa, a matching armchair, and a small table. There are three framed pictures on the wall, a wooden cabinet, and a carpeted floor.

A reception desk with a sign reading "Comfort Inn & Suites" and two monitors on either side.

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

5. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve

Stephanie

￥9,896

￥11,034 total

includes taxes & fees

Sep 20 - Sep 21

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

A Best Western Inn & Suites sign on a building with a clear blue sky and palm trees.

A hotel room with a TV, sofa, coffee table, desk, and a bathroom visible in the background.

A breakfast buffet with various food options, including cereals, pastries, and a sign indicating gluten-free items.

6. Best Western Fort Myers Inn & Suites

3.5 km from Six Mile Cypress Slough Preserve

William

￥10,466

￥11,670 total

includes taxes & fees

Sep 6 - Sep 7

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

A gym with treadmills, elliptical machines, and a stationary bike.

A hotel room with two beds, a desk, and a chair.

A hotel lobby with a reception desk, seating area, and a restaurant.

7. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve

Keilyn

￥10,313

￥11,500 total

includes taxes & fees

Sep 3 - Sep 4

An outdoor seating area with a fire pit, outdoor furniture, and a covered patio.

A modern kitchen with wooden cabinets, a white countertop, and a fruit basket.

A multi-story hotel with a modern design, featuring a central entrance with a covered area and a parking lot with marked spaces.

A modern hotel room with a bed, bedside tables, a lamp, a nightstand, a built-in kitchen with a refrigerator, microwave, and cabinets.

8. TownePlace Suites by Marriott Fort Myers Gulf Coast

9.3 km from Six Mile Cypress Slough Preserve

Jameasha

￥14,756

￥16,453 total

includes taxes & fees

Sep 5 - Sep 6

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

An outdoor patio area with tables and chairs, string lights, and potted plants.

A modern living room with a grey sofa, a wooden accent wall, a coffee table with a plant, and sheer curtains allowing natural light.

A modern reception area with a large abstract mural, a wooden reception desk, and a seating area with a long table and chairs.

9. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas, 5.2 km from Six Mile Cypress Slough Preserve

heather

￥14,176

￥15,806 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

A modern hotel lobby with a seating area, a reception desk, and a flat-screen TV.

A hotel room with a bed, a desk with a computer, a chair, a sofa, a mirror, and a nightstand with a lamp.

A multi-story hotel with a modern design, featuring a parking lot and a covered entrance area.

10. Home2 Suites by Hilton Fort Myers Airport

8.2 km from Six Mile Cypress Slough Preserve

Elio

￥16,195

￥18,057 total

includes taxes & fees

Sep 8 - Sep 9

An outdoor patio with a barbecue area, seating, and string lights.

A hotel with a modern facade, a flagpole with an American flag, and a well-lit entrance.

A lobby with a sofa, two armchairs, a coffee table, a fish tank, and a dining area.

A hotel room with a bed, a desk, a chair, a sofa, a mirror, and artwork on the walls.

11. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes, 9.7 km from Six Mile Cypress Slough Preserve

Yamyd

￥15,550

￥17,337 total

includes taxes & fees

Sep 3 - Sep 4

A hotel room with a bed, a desk, a sofa, an ottoman, two lamps, and a framed picture on the wall.

A hotel with a swimming pool, outdoor seating, and a covered patio area.

A self-service kiosk, two refrigerated display cases, and shelves stocked with snacks and beverages.

A modern kitchen with a central island, wooden cabinets, and a blue accent wall.

12. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes, 9.8 km from Six Mile Cypress Slough Preserve

JANINE

￥17,265

￥19,250 total

includes taxes & fees

Sep 3 - Sep 4

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

A modern living room with a blue sofa, red armchairs, and a coffee table. There are two lamps and a wall art piece above the sofa.

A rooftop patio with outdoor seating, a pool, and palm trees.

13. Hampton Inn & Suites Fort Myers - Colonial Blvd

3.4 km from Six Mile Cypress Slough Preserve

Tania

￥18,154

￥20,241 total

includes taxes & fees

Sep 5 - Sep 6

A multi-story hotel with a clear sky, palm trees, and a sign reading "HYATT PLACE".

A hotel room with a sofa, a bed, a desk, and a TV.

A modern restaurant with large windows, indoor plants, and a variety of seating options.

14. Hyatt Place Fort Myers/at The Forum

6.7 km from Six Mile Cypress Slough Preserve

Joe

￥10,677

￥11,905 total

includes taxes & fees

Sep 7 - Sep 8

A poolside area with outdoor seating, a fire pit, and a building with multiple balconies.

A modern hotel lobby with a curved seating area, a flat-screen TV mounted on the wall, and large windows offering a view of the outdoors.

A modern hotel room with a bed, a sofa, an armchair, a small table, and a large window with curtains.

A modern restaurant with a counter, menu boards, and seating area.

15. Courtyard by Marriott Fort Myers I-75/Gulf Coast Town Center

Miromar Lakes, 10.1 km from Six Mile Cypress Slough Preserve

Mario

￥14,756

￥16,452 total

includes taxes & fees

Sep 5 - Sep 6

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

A modern kitchen with a coffee station, stainless steel appliances, and wooden cabinets.

A modern hotel room with a bed, a desk, a sofa, and a red ottoman.

A modern hotel lobby with a central counter, two refrigerators stocked with beverages, and shelves with snacks.

16. Comfort Suites Fort Myers East I-75

9.6 km from Six Mile Cypress Slough Preserve

monika

￥13,817

￥15,406 total

includes taxes & fees

Sep 20 - Sep 21

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

A hotel room with two beds, wooden headboards, white bedding, a nightstand, a lamp, and a window with a view.

A modern kitchen with a microwave, coffee machines, and a trash bin.

A modern kitchen area with a bar counter, seating, and a coffee station.

17. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor, 5.6 km from Six Mile Cypress Slough Preserve

Sierra

￥8,747

￥9,753 total

includes taxes & fees

Aug 30 - Aug 31

An outdoor patio with a round table, chairs, and a grill.

A modern hotel with a prominent sign reading "Towneplace Suites Marriott." It features a spacious entrance with a covered walkway and a parking lot with handicapped-accessible spaces.

A modern hotel lobby with a sofa, round tables, and a reception desk.

A modern kitchen with wooden cabinets, a central island, pendant lights, and a chalkboard sign saying "A Great Day Starts with Breakfast".

18. Towneplace Suites By Marriott Fort Myers Southeast

4.5 km from Six Mile Cypress Slough Preserve

Linette

￥19,431

￥21,665 total

includes taxes & fees

Sep 10 - Sep 11

A hotel room with a bed, a desk, a chair, and a small table.

A modern kitchen with wooden cabinets, a built-in sink, and a coffee maker.

A hotel with a curved entrance, multiple floors, and a parking area.

A modern hotel lobby with a long reception desk, seating area, and a television mounted on the wall.

19. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor, 3.8 km from Six Mile Cypress Slough Preserve

Samantha

￥15,608

￥17,403 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

A modern hotel lobby with a seating area, a reception desk, and a kitchenette.

A hotel with a swimming pool, outdoor seating, and a sign indicating a 5 ft depth limit.

A spacious lobby with a central seating area, a reception desk, and a vending machine.

20. Home2 Suites by Hilton Fort Myers Colonial Blvd

3.5 km from Six Mile Cypress Slough Preserve

Adolfo

￥17,510

￥19,524 total

includes taxes & fees

Sep 6 - Sep 7

View all properties

Top Six Mile Cypress Slough Preserve Hotel Reviews

Best Western Fort Myers Inn & Suites

10/10 Excellent

"Buen lugar de paso para dormir"

Quality Suites Fort Myers I-75

8/10 Good

"We requested to be moved to another room since the room smelled like mildew. The second room was perfect! The front desk staff were pleasant and helpful. The pool was open and clean. The treadmill wasn’t working in the gym."

Hampton Inn Fort Myers-Airport & I-75

10/10 Excellent

"Great travelers hotel."

Residence Inn by Marriott Fort Myers

8/10 Good

"Its a much older hotel and it looks like it. The Air conditioner in the room was working and you could hear it. They only had one person trying to handle breakfast in the morning, cleaning, cooking, restocking, customer service and that was an impossible task even if there were only 10-20 people there. We ended up going out to breakfast because they ran out of food and I didn't want to further stress out the man who was clearly already stressed. This is our brand of hotel we stay at for all of our Disney Trips and this one wasn't quite what we expected when compared to the Orlando counterparts."

Home2 Suites by Hilton Fort Myers Colonial Blvd

8/10 Good

"The breakfast was, meh. With zero atmosphere."

Hampton Inn & Suites Fort Myers - Colonial Blvd

10/10 Excellent

"Everything was wonderful. Room was very clean with the most quiet ac I have ever experienced at a hotel. The room was super clean! The bed was so soft and comfy. The front desk staff was very friendly. We will be back for our next trip."

Spark by Hilton Fort Myers

10/10 Excellent

"Nice reasonable property."

Landing Fort Myers Near Highland Pines

10/10 Excellent

"Great place to stay with kids."

Cozy Luxury Suite In The Heart Of Fort Myers Close To Everything!

10/10 Excellent

"Great communication and easy check in. Very nice place to stay"

Other attractions near Six Mile Cypress Slough Preserve

Brookshire Bath and Tennis Club

Catch an event at Brookshire Bath and Tennis Club during your trip to Fort Myers.

See properties

Topgolf

You can take time to visit Topgolf during your travels to Fort Myers. Amble around the area's beautiful beaches or attend a baseball game.

See properties

Hammond Stadium

Catch an event at Hammond Stadium during your trip to Fort Myers.

See properties

Lee Health Sports Complex

8.6/10 (432 reviews)

Catch an event at Lee Health Sports Complex during your trip to Fort Myers. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.

See properties

Calusa Nature Center and Planetarium

You can spend time studying the exhibits at Calusa Nature Center and Planetarium in Fort Myers. Stroll along the beautiful beaches or attend a baseball game in the area.

See properties

Eagle Ridge Golf Club

Enjoy a round of golf in Fort Myers at Eagle Ridge Golf Club. Stroll along the beautiful beaches or discover the beautiful sunsets in this family-friendly area.

See properties

The Ranch Concert Hall & Saloon

You can make plans for a show at The Ranch Concert Hall & Saloon during your trip to Fort Myers. In the area, take in the great live music and beautiful sunsets.

See properties

Regal Belltower

You can take time to visit Regal Belltower during your travels to Fort Myers. Amble around this relaxing area's beautiful beaches and enjoy its top-notch restaurants.

See properties

Frequently asked questions

What's the area like around Six Mile Cypress Slough Preserve?

Six Mile Cypress Slough Preserve is located in a family-friendly area of Fort Myers known for its beautiful beaches and bird watching. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Six Mile Cypress Slough Preserve?

Landing Fort Myers Near Highland Pines is one of the top choices for your stay based on our traveler data, and this aparthotel offers an outdoor pool and free parking. It's located just a short 1 mi (1.6 km) from Six Mile Cypress Slough Preserve. Other good choices within 5 miles include Baymont by Wyndham Fort Myers Central and HomeTowne Studios by Red Roof Fort Myers.

How many hotels will I find close to Six Mile Cypress Slough Preserve?

Expedia has 22 hotels and other accommodations within a mile from Six Mile Cypress Slough Preserve.

If I need to cancel the hotel reservation for my stay near Six Mile Cypress Slough Preserve, will I receive a refund?

Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals near Six Mile Cypress Slough Preserve.

Where can I learn more about changing or cancelling my trip in the area near Six Mile Cypress Slough Preserve?

For more information about changing or cancelling your stay near Six Mile Cypress Slough Preserve, head over to our customer service page.

What can I see and do near Six Mile Cypress Slough Preserve?

You can check out the local talent at Barbara B Mann Hall, The Ranch Concert Hall & Saloon, and Broadway Palm Dinner Theatre. You might spend a leisurely day outdoors at Lakes Regional Park and Dunbar Park. Calusa Nature Center and Planetarium, Alliance for the Arts, and Railroad Museum of South Florida are fun stops for the whole family while you're in town.

Find hotels near Six Mile Cypress Slough Preserve, Fort Myers from ￥9,753

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Six Mile Cypress Slough Preserve hotels

1. HomeTowne Studios by Red Roof Fort Myers

2. 2 Mi to Six Mile Preserve! Family Getaway w/ Pool

3. Hampton Inn Fort Myers-Airport & I-75

4. Holiday Inn Express & Suites Fort Myers Airport by IHG

5. Comfort Inn & Suites Fort Myers Airport

6. Best Western Fort Myers Inn & Suites

7. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

8. TownePlace Suites by Marriott Fort Myers Gulf Coast

9. Doubletree by Hilton Fort Myers at Bell Tower Shops

10. Home2 Suites by Hilton Fort Myers Airport

11. Homewood Suites by Hilton Fort Myers Airport/FGCU

12. Drury Inn & Suites Fort Myers Airport FGCU

13. Hampton Inn & Suites Fort Myers - Colonial Blvd

14. Hyatt Place Fort Myers/at The Forum

15. Courtyard by Marriott Fort Myers I-75/Gulf Coast Town Center

16. Comfort Suites Fort Myers East I-75

17. Extended Stay America Premier Suites - Fort Myers - Airport

18. Towneplace Suites By Marriott Fort Myers Southeast

19. SpringHill Suites by Marriott Fort Myers Airport

20. Home2 Suites by Hilton Fort Myers Colonial Blvd

Top Six Mile Cypress Slough Preserve Hotel Reviews

Best Western Fort Myers Inn & Suites

Quality Suites Fort Myers I-75

Hampton Inn Fort Myers-Airport & I-75

Residence Inn by Marriott Fort Myers

Home2 Suites by Hilton Fort Myers Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd

Spark by Hilton Fort Myers

Landing Fort Myers Near Highland Pines

Cozy Luxury Suite In The Heart Of Fort Myers Close To Everything!

Other attractions near Six Mile Cypress Slough Preserve

Brookshire Bath and Tennis Club

Topgolf

Hammond Stadium

Lee Health Sports Complex

Calusa Nature Center and Planetarium

Eagle Ridge Golf Club

The Ranch Concert Hall & Saloon

Regal Belltower

Frequently asked questions