Find hotels in Santo Tomé from ￥1,592

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 25 - Aug 26
Tomorrow
Aug 26 - Aug 27
This weekend
Aug 29 - Aug 31
Next weekend
Sep 5 - Sep 7

Filter by

Guest rating
Guest rating
Star rating

Compare 134 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santo Tomé

Head to Getulio Vargas Museum and Joao Goulart Museum—just two of the sights around Santo Tomé.

See all hotels in Santo Tomé

Top Santo Tomé Hotel Reviews

More cheap stays in Santo Tomé

More cheap stays in Santo Tomé

Apart Hotel Las Violetas

Apart Hotel Las Violetas

Barrio del Lago, 3008, Candelaria, Misiones
Get rates

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

If I need to cancel my hotel reservation in Santo Tomé, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santo Tomé.

Where can I learn more about changing or cancelling my trip to Santo Tomé?

For more details about updating your trip to Santo Tomé or cancelling it, click here.

What should I see while I'm in Santo Tomé?

Places to visit in the wider area include Getulio Vargas Museum and Joao Goulart Museum. Check out what more to see and do in Expedia's Santo Tomé guide.

What's the weather like in Santo Tomé?

The hottest months are usually January and February with an average temp of 78°F, while the coldest months are July and June with an average of 60°F. The rainiest months in Santo Tomé are October, November, March, and January, with each month seeing an average of 8 inches of rainfall.