Santo Domingo Vacation Rentals

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Check prices for these dates

Tonight
Dec 20 - Dec 21
Tomorrow
Dec 21 - Dec 22
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Our top choices for Santo Domingo vacation rentals

Exterior detail
Nostra Casa Vagón

Vacation Home in Coamo

Nostra Casa Vagón
2.0 star property
10.0 out of 10, Exceptional, (1)
"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "
United States
Carlos Reyes
The price is ￥8,714
￥20,608 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Nostra Casa Vagón
Terrace/patio
The Place at the Sea

Aparthotel in Ponce

The Place at the Sea
2.0 star property
9.2 out of 10, Wonderful, (214)
"Everything was excellent, rooms super clean, friendly staff. Great location right by the beach. Will definitely stay on our next vacations."
United States
Ednardo
The Place at the Sea
Fridge, coffee/tea maker, cookware/dishes/utensils, lobster pot
Hacienda Vista Del Rio 1

Apartment in Orocovis

Hacienda Vista Del Rio 1
The price is ￥7,780
￥30,218 total
includes taxes & fees
Dec 25 - Dec 26
Hacienda Vista Del Rio 1
Fridge, oven, stovetop, coffee/tea maker
Apartamento Vista Del Río #2

Apartment in orocovis

Apartamento Vista Del Río #2
The price is ￥8,558
￥32,194 total
includes taxes & fees
Dec 22 - Dec 23
Apartamento Vista Del Río #2
Comfort Studio | Living area | Smart TV
Chandelier 301

Apartment in Ponce Centro

Chandelier 301
3.0 star property
7.0 out of 10, Good, (8)
"Great stay if you are touring the area. Very secured spot and close to a lot of places. "
United States
Luis
The price is ￥17,505
￥22,893 total
includes taxes & fees
Dec 24 - Dec 25
Chandelier 301
Beach
Homey Escape with Patio Access and FREE Laundry

Apartment in Ponce

Homey Escape with Patio Access and FREE Laundry
9.0 out of 10, Wonderful, (17)
"Easy check in. Sweet people. "
United States
Dene
The price is ￥9,654
￥21,080 total
includes taxes & fees
Dec 22 - Dec 23
Homey Escape with Patio Access and FREE Laundry
Beach
Private Patio Retreat with Zen Vibe and Laundry

Apartment in Ponce

Private Patio Retreat with Zen Vibe and Laundry
9.2 out of 10, Wonderful, (11)
"Better than expected perfect location cleaned up-to-date modern I will definitely book again"
United States
Anonymous traveler
The price is ￥11,043
￥22,567 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Private Patio Retreat with Zen Vibe and Laundry
TV
Beautiful Chandeliers, Cozy & Enjoyable Studio - Balcony / FREE WIFI - 302

Apartment in Ponce Centro

Beautiful Chandeliers, Cozy & Enjoyable Studio - Balcony / FREE WIFI - 302
8.0 out of 10, Very Good, (1)
"Deberian darle acceso a la piscina a todos los huespedes."
Mexico
Yesenia
The price is ￥19,450
￥28,397 total
includes taxes & fees
Dec 21 - Dec 22
Beautiful Chandeliers, Cozy & Enjoyable Studio - Balcony / FREE WIFI - 302
Beach
Spacious Retreat with Private Jacuzzi and Tropical Patio

Vacation Home in Ponce

Spacious Retreat with Private Jacuzzi and Tropical Patio
10.0 out of 10, Exceptional, (1)
"This property was convenient, super clean and had everything that we needed! "
United States
Heather L.
The price is ￥17,116
￥33,026 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Spacious Retreat with Private Jacuzzi and Tropical Patio
Beach
Private Jacuzzi Oasis with Mountain Views. FREE Parking and Laundry

Apartment in Ponce

Private Jacuzzi Oasis with Mountain Views. FREE Parking and Laundry
7.6 out of 10, Good, (7)
"The home is lovely! Has good WiFi access, the kitchen is modern & functional! Getting here from the airport was literally a breeze after picking up our rental from the airport! Check-in took longer than expected b/c the host provided us the wrong code, he took a while to respond but eventually we got in! "
United States
Ray G.
The price is ￥19,719
￥36,015 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Private Jacuzzi Oasis with Mountain Views. FREE Parking and Laundry
Beach
Luxury Retreat with Private Jacuzzi and Mountain Views. FREE Parking and Laundry

Apartment in Ponce

Luxury Retreat with Private Jacuzzi and Mountain Views. FREE Parking and Laundry
9.2 out of 10, Wonderful, (10)
"Had a lovely time. The apartment was great, with an excellent location. Armando was a great host. Would definitely recommend to a friend."
United States
Gail C.
The price is ￥18,205
￥34,036 total
includes taxes & fees
Dec 21 - Dec 22
Luxury Retreat with Private Jacuzzi and Mountain Views. FREE Parking and Laundry
Smart TV
Gladiolas 1102 - This is it Puerto Rico

Apartment in Ponce Centro

Gladiolas 1102 - This is it Puerto Rico
10.0 out of 10, Exceptional, (2)
"Muchos sitios de comida buenos alrededor y los mantecados. Área tranquila y con mucha seguridad."
United States
Griselle
The price is ￥16,533
￥24,965 total
includes taxes & fees
Dec 21 - Dec 22
Gladiolas 1102 - This is it Puerto Rico
Smart TV
Savvy’s Place

Apartment in Ponce Centro

Savvy’s Place
10.0 out of 10, Exceptional, (2)
"Very clean, good location, beautiful place. Definitely recommend!! "
United States
Karina G.
The price is ￥14,471
￥29,574 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Savvy’s Place
Interior
Gladioli 1206 - That's all Puerto Rico

Apartment in Ponce Centro

Gladioli 1206 - That's all Puerto Rico
The price is ￥21,006
￥29,906 total
includes taxes & fees
Dec 22 - Dec 23
Gladioli 1206 - That's all Puerto Rico
Apartment, 1 Bedroom | Living area | Flat-screen TV
Gladiolas 2202

Apartment in Ponce Centro

Gladiolas 2202
3.0 star property
7.4 out of 10, Good, (8)
"I like that it was close to different type of restaurants. "
United States
rosy
The price is ￥22,336
￥28,061 total
includes taxes & fees
Dec 21 - Dec 22
Gladiolas 2202
Beach
Expansive Paradise with Private Jacuzzi and Tropical Patio

Vacation Home in Ponce

Expansive Paradise with Private Jacuzzi and Tropical Patio
The price is ￥26,029
￥50,094 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Expansive Paradise with Private Jacuzzi and Tropical Patio
Smart TV
Modern and Colonial - Gladiolas II /Room Plus /Queen Bed /Free WIFI /AC - 2202

Apartment in Ponce Centro

Modern and Colonial - Gladiolas II /Room Plus /Queen Bed /Free WIFI /AC - 2202
8.0 out of 10, Very Good, (2)
"It was fine."
United States
Daisy S.
The price is ￥22,874
￥32,165 total
includes taxes & fees
Dec 21 - Dec 22
Modern and Colonial - Gladiolas II /Room Plus /Queen Bed /Free WIFI /AC - 2202
Terrace/patio
3-bedroom apartment in delightful Ponce with Patio, Parking and Laundry

Apartment in Ponce

3-bedroom apartment in delightful Ponce with Patio, Parking and Laundry
The price is ￥23,340
￥44,782 total
includes taxes & fees
Dec 22 - Dec 23
3-bedroom apartment in delightful Ponce with Patio, Parking and Laundry
Property grounds
Apartment Double Bed- Sleeps 2 - Free WIFI

Apartment in Ponce Centro

Apartment Double Bed- Sleeps 2 - Free WIFI
6.0 out of 10, (5)
"I stayed for 10 days, it was great. Location, amenities, locals and the Host was great. Amazing services! Keep up the great work. Would recommend ."
United States
ErnestV
The price is ￥7,490
￥19,056 total
includes taxes & fees
Dec 22 - Dec 23
Apartment Double Bed- Sleeps 2 - Free WIFI
Beach
Compact Haven with Private Entrance and FREE Parking and Laundry

Apartment in Ponce

Compact Haven with Private Entrance and FREE Parking and Laundry
9.2 out of 10, Wonderful, (17)
"Apartment was very good, location was close to everything. Off street parking great."
United States
Anonymous traveler
The price is ￥10,648
￥22,145 total
includes taxes & fees
Dec 22 - Dec 23
Compact Haven with Private Entrance and FREE Parking and Laundry
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Domingo Hotel Reviews

Holiday Inn Ponce & Tropical Casino by IHG

Holiday Inn Ponce & Tropical Casino by IHG

10/10 Excellent
"Did not have breakfast at the hotel nor did I use the bar "
Julio 2-night trip
Posted 3 days ago
Holiday Inn Ponce & Tropical Casino by IHG

Find out more about Santo Domingo

Search for holiday rentals in Santo Domingo on Expedia! You can easily find your home rentals, villas, holiday apartments in Santo Domingo using one of the methods below:

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Look no further and take a look at our great range of rental properties in Santo Domingo!

Frequently asked questions

Can I find a vacation rental in Santo Domingo?

Yes, we have vacation rentals close to popular attractions in Santo Domingo, or you can select a more secluded option if you'd like a relaxing place to stay.

What are some of the best vacation rentals that Santo Domingo has to offer?

Beautiful and roomy residence close to nature adventure attractions!: This vacation home rental outside of Santo Domingo is located on a lake and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You can relax into your vacation with a hot tub and a selection of books.

What’s there to see and do in Santo Domingo?

Explore the area and family-friendly sights such as Castillo del Niño, or get out into nature at a spot like Playa de Tamarindo. In the larger area, you’ll find Guayanilla Bay and Hacienda Buena Vista.

What’s a vacation rental in Santo Domingo like?

A vacation rental is a private property you can book for a long or short time in Santo Domingo. Vacation rentals offer extras like laundry facilities and kitchens so you'll have everything you need. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a small group gathering.