Santiago Vacation Rentals

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Vacation Rentals in Santiago

Aparthotel in Jobos

2.5 star property
4.8 out of 10, (45)
"Loved it "
United States
Ingry N
The price is ¥20,970
¥22,438 total
includes taxes & fees
Dec 9 - Dec 10
Jobos Luxury Condos

Aparthotel in Aguadilla

2.5 star property
9.8 out of 10, Exceptional, (102)
"Staff was kind and courteous, room was modern and clean. "
United States
Vincent
The price is ¥21,910
¥26,270 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Aguadilla Surf Lodge

Vacation Home in Isabela

3.5 star property
9.0 out of 10, Wonderful, (35)
"Very comfortable apartment (1st floor) will definitely rent again."
United States
Abimael
Colinas del Atlantico Vacational House 1st Floor

Villa in Hatillo

9.2 out of 10, Wonderful, (49)
"Very comfortable home with a great pool area in a quiet neighborhood. Great for large families or a group of friends. One of the rooms is detached and by the pool with its own bathroom which was great for our needs. While there are a few areas of the house that could use some improvements, the host is extremely accommodating and quick to respond, which makes up for any minor issues."
United States
Cynthia M.
The price is ¥74,558
¥131,564 total
includes taxes & fees
Dec 15 - Dec 16
Utopia Luxury Villa - Private Pool, Hydromassage Jacuzzi & Near Amazing Beaches

Vacation Home in Isabela

3.5 star property
9.0 out of 10, Wonderful, (48)
"Good amount of space, beds & pillows were comfortable. Hosts were responsive. House was clean. My only complaint was that power went out for about 5 hours and it was hot! I also didn’t like that it was high up on a long road with many turns and barely visible street signs. This aside, it was fine with enough room for all."
United States
Lillian
The price is ¥8,646
¥27,461 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Casa vacacional en Arenales Isabela

Apartment in Arecibo

2.5 star property
7.0 out of 10, Good, (249)
"Is a nice place to relax and stepping out from your normal life routine. The pool and the beach so near are the best combo. The staff is very friendly and helpful. Love the place. "
United States
Reinaldo E.
The price is ¥16,931
¥23,863 total
includes taxes & fees
Dec 9 - Dec 10
Ventana al Atlantico at Arecibo 681 Ocean Drive

Condo in Isabela, PR

9.8 out of 10, Exceptional, (183)
"Beautiful and peaceful!!! "
United States
Leila
Million Dollar View, Guaranteed! 4br, 3ba Corner Penthouse, Jobos' Beach Isabela

Apartment in Isabela

9.6 out of 10, Exceptional, (73)
"Yes enjoyed my stay very clean view is nice. Only downside is basically like on a 4th floor all stairs no elevator. It’s quite close to the beach. Restaurants are very accessible near the apartments. "
United States
Glenda Ivelise De S.
Beachfront Modern Loft with Large Private Terrace

Villa in Jarealito

9.6 out of 10, Exceptional, (257)
"My stay at the beach house in Arecibo, Puerto Rico was unforgettable. The property was incredibly clean and well-maintained, making it feel like a true home away from home. The private pool was stunning—crystal clear and perfect for relaxing any time of day. Best of all, the beach was just steps away, giving us easy access to breathtaking ocean views and peaceful walks along the shore. The combination of comfort, beauty, and location made this an amazing experience I’d absolutely recommend."
United States
james w.
Escape to Beach Paradise & Light House -The Best for Families & Great for Events

Villa in Isabela

9.8 out of 10, Exceptional, (69)
"Lovely stay would highly recommend and will def be back!! "
United States
Jennifer R.
Room with a View! Stay LOVE PLAY on the beach in Isabela, between Jobos & Shacks

Vacation Home in Utuado

9.6 out of 10, Exceptional, (86)
"This property is ideal for our needs. It has everything one needs for a stay. Just bring your clothes."
United States
Jose Orlando R.
Beautiful and roomy residence close to nature adventure attractions!

Vacation Home in Jarealito

9.8 out of 10, Exceptional, (17)
"We had an amazing 3 week vacation in PR with friends and family!! This house fit our needs and made our trip!! The beach is amazing and not crowded. The pool was perfect. We cooked, ate, relaxed and had so much fun here! And as an added bonus the restaurant across the street had fabulous food and the best margaritas!! I would recommend this house to all!!!"
United States
Jeanne P.
Blue Nest at the Beach

Condo in Isabela

9.8 out of 10, Exceptional, (23)
"Great location, great property, excellent communication!"
United States
Sara P.
#20 Stunning 4BR Beachfront Penthouse Jobos Beach

Vacation Home in Moca

3.5 star property
8.4 out of 10, Very Good, (44)
"Best thing was the location and lots of space. But did not feel like the safest place and also a pretty bad smell in one bathroom due to a jacuzzi (said temporary under construction, but it seem"
United States
Britta
Big vacational house in Isabela

Villa in Isabela

3.5 star property
9.2 out of 10, Wonderful, (39)
"Grate place to stay wife and kid's love it will stay again "
United States
Jonathan
The price is ¥12,395
¥32,873 total
includes taxes & fees
Dec 11 - Dec 12
Golden Dream Villas 306 A

Vacation Home in Isabela

3.5 star property
9.4 out of 10, Exceptional, (12)
"This property was spacious and great for our family of 14"
United States
Maria
The price is ¥23,626
¥52,539 total
includes taxes & fees
Dec 9 - Dec 10
Colinas del Atlantico for 18 People

Vacation Home in Aguadilla

3.5 star property
10.0 out of 10, Exceptional, (1)
"Great place to stay while visiting Puerto Rico. Large property with recreational area and pool. Careful when walking through grass red fire ants! Typical in PR. Listen to the coquis at night . Laundry area was convenient. "
United States
Vincent Gabriel
Granero Kenyard

Vacation Home in Isabela

3.5 star property
8.0 out of 10, Very Good, (33)
"The apartment was great in great conditiond an lots of space. "
United States
Samarie
The price is ¥6,848
¥24,974 total
includes taxes & fees
Dec 10 - Dec 11
Colinas del Atlantico Vacational House 2nd Floor

Vacation Home in Jobos

9.8 out of 10, Exceptional, (100)
"We had a family member get married at this part of the island and had a large group. This house was SO perfect for everything our family needed! So close to the beach (Jobos beach is the best! Cafes (Good Start!) And food trucks within walking distance. A oerfect memorabke vacation!!And food tricks in walkimg "
United States
Geri J.
Steps from Water & Restaurants, right at Jobos beach!, Great Location!

Aparthotel in Arecibo

2.5 star property
9.0 out of 10, Wonderful, (2)
"Angel worked us in on a same-day booking and met with us at 9:00pm for check and was truly a holiday life-saver (thanks to a different VRBO booking never responding on check in). Nice amenities and right next to ocean (more surfing spot rather than swimming, but pool was nice as well). With more times notice and some updates, this place could easily be 5 star. Again, super thanks to Angel for the last-minute accomodations."
United States
Justin
The price is ¥29,823
¥41,895 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Casita Linda
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santiago Hotel Reviews

Find out more about Santiago

Search for holiday rentals in Santiago on Expedia! You can easily find your home rentals, villas, holiday apartments in Santiago using one of the methods below:

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Look no further and take a look at our great range of rental properties in Santiago!

Frequently asked questions

Can I find a vacation rental in Santiago?

Yes, we have vacation rentals near top sights in Santiago, or you can go with a secluded option if you're looking for a relaxing stay.

What's the top vacation rental that Santiago has to offer?

Colinas del Atlantico Vacational House 1st Floor: This vacation home rental near Santiago offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

What can I see and do in Santiago?

While exploring the area, visit family-friendly sights like Arecibo Observatory, or get outside and enjoy nature at Río Camuy. Camuy River Cave Park and Playa Peñón Brusi are a couple of places you'll find in the larger area.

What are vacation rentals like in Santiago?

Vacation rentals are private accommodations you can book for a short or long stay in Santiago. Vacation rentals feature extras like laundry facilities and kitchens so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from shared hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive choice for a family getaway.