A valley with a town nestled between hills, a winding road, and distant mountains.

Search Vacation Homes in Santee

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Santee vacation homes

1. Spacious 4-bedroom house with AC, fitness equipment in wonderful Lakeside

Spacious 4-bedroom house with AC, fitness equipment in wonderful Lakeside
Lakeside
9.6 out of 10, Exceptional, (7 reviews)
"From the check in process to the stay it was a great experience . The house was clean and well stocked with everything needed to enjoy our stay"
United States
Timothy C.
The price is ￥29,852
￥84,441 total
includes taxes & fees
Sep 29 - Sep 30
Spacious 4-bedroom house with AC, fitness equipment in wonderful Lakeside
A hotel with a large building, a pond with rocks and plants, and a bridge.

2. Private Casita located near San Diego attractions with free onsite laundry

Private Casita located near San Diego attractions with free onsite laundry
Lakeside
9.8 out of 10, Exceptional, (7 reviews)
"We had an amazing stay! Beautiful home with a beautiful view. Brent and Carla were very responsive to any questions. My wife and 12 month old stayed for 3 nights and we had everything we needed. The house is also very baby friendly!"
United States
Daniel C.
The price is ￥22,648
￥46,290 total
includes taxes & fees
Sep 29 - Sep 30
Private Casita located near San Diego attractions with free onsite laundry
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table with upholstered chairs.

3. La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.0 out of 10, Wonderful, (11 reviews)
"The property was well located for us. "
United States
Ann D.
The price is ￥27,524
￥79,584 total
includes taxes & fees
Sep 30 - Oct 1
La Mesa Family Retreat - 20 minutes to Beaches & More!
A gravel pathway with red bricks leading to a gate.

4. La Casita Guest House, private fenced yard & with heat and AC, pet friendly

La Casita Guest House, private fenced yard & with heat and AC, pet friendly
Mount Helix
9.8 out of 10, Exceptional, (13 reviews)
"Thank you so much for the hospitality and your kindness"
United States
Lisa D.
The price is ￥18,874
￥47,074 total
includes taxes & fees
Oct 5 - Oct 6
La Casita Guest House, private fenced yard & with heat and AC, pet friendly
A modern dining area with a long table set for six, a kitchen in the background, and a view of the outdoors.

5. Villa Del Cerro

Villa Del Cerro
Del Cerro
9.4 out of 10, Exceptional, (28 reviews)
"We had a great stay. Beautiful home with lots of activities. Great for a family reunion or retirement gathering. Would love to stay here again! "
United States
Tera F.
The price is ￥64,831
￥165,251 total
includes taxes & fees
Oct 1 - Oct 2
Villa Del Cerro
A deck with two wicker chairs and a small table, overlooking a mountainous landscape and a body of water.

6. Luxury Studio with Lake Views and Spacious Balcony

Luxury Studio with Lake Views and Spacious Balcony
Spring Valley
7.8 out of 10, Good, (7 reviews)
"It was beautiful and very modern. We loved it and hope to come back again!! "
United States
Ronette B.
The price is ￥13,212
￥31,570 total
includes taxes & fees
Oct 25 - Oct 26
Luxury Studio with Lake Views and Spacious Balcony
A living room with a beige sofa, two armchairs, a coffee table, and a rug. There are two lamps, a painting on the wall, and a window with a view of greenery and a blue car outside.

7. 'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!

'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
Encanto
8.8 out of 10, Excellent, (40 reviews)
"Beds were very comfortable."
United States
Paula
The price is ￥12,740
￥37,903 total
includes taxes & fees
Sep 29 - Sep 30
'Ted' 2-bedroom cozy house in central location! 10 minutes to Balboa!
An outdoor dining area with a view of the sunset, a pool, and a pergola.

8. The Overlook at Vista Verde

The Overlook at Vista Verde
Tierrasanta
10.0 out of 10, Exceptional, (22 reviews)
"Beautiful property, great pool, tons of space with good bedrooms for many adults. "
United States
Amy P.
The Overlook at Vista Verde
A living room with a blue sofa, a round coffee table, and a world map on the wall.

9. Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very good, (4 reviews)
"We thoroughly appreciated the communications provided by the host. Initially had a few teething issues, with the keylock code not working, and a smell in the bedroom and the living area, but this was rectified and a cleaning crew came in twice for it. Place is perfectly situated (with car use) but a bit less so if on foot, or public transportation. The laundry in the shed and the kitchen are always welcome especially as our booking was over 2 weeks long! Thanks again for a suitable stay for us!"
United States
Carlo Luis
The price is ￥16,816
￥67,460 total
includes taxes & fees
Sep 29 - Sep 30
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
A modern living room with a sofa, coffee table, and a dining area with chairs and a table.

10. Modern Hideaway in North Park - 3941

Modern Hideaway in North Park - 3941
North Park
10.0 out of 10, Exceptional, (3 reviews)
"Such a great experience here! The host was very communicative and attentive. Spot was clean and perfect for our weekend getaway. There are plenty of bars and cool shops within walking distance. We will definitely be booking the same spot on our next trip!"
United States
Madison S.
Modern Hideaway in North Park - 3941
A pool with a waterfall feature, surrounded by lounge chairs and a patio area.

11. The Outside Inn at The Tipsy Goat Ranch

The Outside Inn at The Tipsy Goat Ranch
Lakeside
10.0 out of 10, Exceptional, (28 reviews)
"Host was fantastic. Property is exactly as described, unique place to stay and definitely memorable."
United States
Tom D.
The price is ￥27,320
￥44,621 total
includes taxes & fees
Oct 7 - Oct 8
The Outside Inn at The Tipsy Goat Ranch

12. Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!

Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!
Spring Valley
9.2 out of 10, Wonderful, (9 reviews)
"Location was perfect for our needs. Great space for the dogs too. "
United States
Hayley G.
The price is ￥23,592
￥57,999 total
includes taxes & fees
Oct 1 - Oct 2
Mid-Century Treehouse with Yard and Views! AMAZING Location! Pet-friendly!
A modern living room with a grey sofa, a small round coffee table, and a ceiling fan.

13. Charming 1-bedroom house in Beautiful San Diego with WiFi, AC

Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
Mid-City
10.0 out of 10, Exceptional, (2 reviews)
"Our stay was excellent. We enjoyed the space. Used TV, sofa and bed… nothing else. Quiet and easy access to property. "
United States
Socorro C.
The price is ￥22,019
￥45,705 total
includes taxes & fees
Sep 29 - Sep 30
Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
A poolside area with wicker chairs, a table with a bottle and glasses, and a view of a building and pool at dusk.

14. Ultimate Group Getaway—Pool, Spa, Views, Games!

Ultimate Group Getaway—Pool, Spa, Views, Games!
San Carlos
9.6 out of 10, Exceptional, (33 reviews)
"Wonderful little oasis - so great for our family gathering with young children"
United States
Steven N.
The price is ￥46,398
￥128,394 total
includes taxes & fees
Oct 18 - Oct 19
Ultimate Group Getaway—Pool, Spa, Views, Games!
An outdoor patio with a table and chairs, string lights, and a grill.

15. 3 Bedroom House - Fire Pit Table, BBQ - 10 Guests

3 Bedroom House - Fire Pit Table, BBQ - 10 Guests
La Mesa
9.2 out of 10, Wonderful, (15 reviews)
"Adam was great! Communicated regularly and ensured I was good to go from the start. "
United States
Beth H.
3 Bedroom House - Fire Pit Table, BBQ - 10 Guests
A modern hotel room with a large bed, a TV, a desk, and a bathroom visible through an open door.

16. Family Haven: Sports Court, Game Room, King Beds

Family Haven: Sports Court, Game Room, King Beds
Fletcher Hills
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful stay - kids had an amazing time in the game room/garage."
United States
Calvin C.
The price is ￥50,330
￥100,188 total
includes taxes & fees
Sep 29 - Sep 30
Family Haven: Sports Court, Game Room, King Beds
A living room with a flat-screen TV on a wooden wall, a sofa, a coffee table with a tray, and a door leading to another room.

17. SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.

SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.
Mid-City
9.4 out of 10, Exceptional, (19 reviews)
"The location was great for getting to all the top attractions in San Diego. The back yard and garden was very peaceful and great for kids to explore!"
United States
Jenna T.
The price is ￥23,435
￥57,411 total
includes taxes & fees
Oct 20 - Oct 21
SanDiego Insider's Coastal Bliss and Urban Wonders. Near SDSU Chollas Lake.
A modern kitchen with a large island, stainless steel appliances, and pendant lighting.

18. Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access

Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
La Mesa
9.0 out of 10, Wonderful, (10 reviews)
"We had a wonderful stay! The home is lovely, clean and exactly as described. Jonathan is very nice and easy to communicate with. We loved staying here to celebrate our son’s graduation from SDSU!"
United States
Anonymous traveler
The price is ￥31,456
￥69,203 total
includes taxes & fees
Sep 29 - Sep 30
Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
A dining area with a large table, blue chairs, and a view of palm trees and mountains.

19. Luxury Hilltop Estate I Resort Pool I Sunset Views

Luxury Hilltop Estate I Resort Pool I Sunset Views
Rancho San Diego
9.8 out of 10, Exceptional, (21 reviews)
"We had a fantastic time, highly recommend staying that this property! "
United States
Alex E.
The price is ￥81,959
￥186,865 total
includes taxes & fees
Oct 4 - Oct 5
Luxury Hilltop Estate I Resort Pool I Sunset Views
A modern living room with a flat-screen TV, a dining area with a white table and green chairs, and a hallway with a door.

20. Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking

Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking
La Mesa
10.0 out of 10, Exceptional, (1 review)
The price is ￥26,876
￥56,916 total
includes taxes & fees
Oct 4 - Oct 5
Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

The Sofia Hotel

The Sofia Hotel

10/10 Excellent
"Great location"
Mirko 7-night trip
Posted less than an hour ago
The Sofia Hotel

Find out more about Santee

Santee Vacation Homes information

Number of reviews
214
Accommodation
3704 Vacation Homes
Lowest Price
￥31,570
Highest Price
￥186,865