The Best Hotels Closest to Santee National Wildlife Refuge in Summerton for 2026

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Our top choices for Santee National Wildlife Refuge hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

1. Fairfield Inn & Suites by Marriott Santee

7 km from Santee National Wildlife Refuge

Victor

￥22,984 total

includes taxes & fees

Nov 19 - Nov 20

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

2. Hampton Inn Santee-I-95

7 km from Santee National Wildlife Refuge

sandra

￥22,054 total

includes taxes & fees

Dec 13 - Dec 14

A hotel entrance with a sign reading "Best Western PLISS."

3. Best Western Plus Santee Inn

7 km from Santee National Wildlife Refuge

Johnny

￥21,106 total

includes taxes & fees

Nov 22 - Nov 23

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

4. Tru By Hilton Santee

7.2 km from Santee National Wildlife Refuge

Armando

￥18,556 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with a bed, bedside table, lamp, and a mirror.

5. Baymont by Wyndham Santee

7.2 km from Santee National Wildlife Refuge

Thomas

￥14,186 total

includes taxes & fees

Nov 15 - Nov 16

A water park with a pool, slides, and umbrellas.

6. Holiday Inn Santee by IHG

7.2 km from Santee National Wildlife Refuge

Traci

￥21,474 total

includes taxes & fees

Dec 13 - Dec 14

A hotel room with two beds, a desk, a chair, and a mirror.

7. SureStay Hotel by Best Western Manning

25.7 km from Santee National Wildlife Refuge

Tina

￥14,521 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

8. Comfort Inn & Suites Santee

7.2 km from Santee National Wildlife Refuge

Alexis

￥19,099 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.

9. Travelodge by Wyndham Santee

7.1 km from Santee National Wildlife Refuge

Robert

￥11,524 total

includes taxes & fees

Nov 26 - Nov 27

A hotel room with a bed, a black armchair, a round mirror with lights, a black vanity with a sink, and a white towel on the wall.

10. Starlight Stays

19.8 km from Santee National Wildlife Refuge

tevin

￥8,603 total

includes taxes & fees

Nov 18 - Nov 19

A dining area with multiple tables and chairs, a ceiling fan, and large windows.

11. Super 8 by Wyndham Santee/I-95

7 km from Santee National Wildlife Refuge

William

￥11,306 total

includes taxes & fees

Nov 19 - Nov 20

A hotel lobby with multiple seating areas, a reception desk, and a television.

12. Hampton Inn Manning

25.6 km from Santee National Wildlife Refuge

Clayton

￥24,872 total

includes taxes & fees

Nov 29 - Nov 30

A cabin with a porch, surrounded by trees and a body of water.

13. Red Roof Inn Santee

7 km from Santee National Wildlife Refuge

Sharyn

￥11,171 total

includes taxes & fees

Nov 16 - Nov 17

A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

14. Quality Inn & Suites Santee I-95

6.9 km from Santee National Wildlife Refuge

Louis

￥10,445 total

includes taxes & fees

Dec 2 - Dec 3

A bathroom with a large bathtub, a mirror, a sink, and a television.

15. Baymont by Wyndham Manning

25.3 km from Santee National Wildlife Refuge

Willian

￥14,187 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

16. Econo Lodge Santee

7.1 km from Santee National Wildlife Refuge

Arthur

￥11,185 total

includes taxes & fees

Dec 7 - Dec 8

A hotel room with two beds, a chair, a lamp, and a curtain.

17. Best Inn of Manning

25.5 km from Santee National Wildlife Refuge

ROLLIE

￥10,850 total

includes taxes & fees

Dec 13 - Dec 14

A buffet with various food items and utensils.

18. Sunset Inn Manning I 95

18.9 km from Santee National Wildlife Refuge

James

￥9,089 total

includes taxes & fees

Nov 14 - Nov 15

A building with a large entrance, multiple windows, and potted plants in the foreground.

19. Ashburn Inn Manning I 95

18.8 km from Santee National Wildlife Refuge

￥12,788 total

includes taxes & fees

Nov 14 - Nov 15

A poolside area with lounge chairs, umbrellas, and stone tables.

20. Clark's Inn

7.1 km from Santee National Wildlife Refuge

￥30,422 total

includes taxes & fees

Nov 21 - Nov 22

View all properties

Compare popular hotels close to Santee National Wildlife Refuge

Property	Star rating	Guest rating
Fairfield Inn & Suites by Marriott Santee	3.0 star property	9.8 Exceptional 1,001 reviews	View
Hampton Inn Santee-I-95	2.5 star property	9.6 Exceptional 1,001 reviews	View
Best Western Plus Santee Inn	2.5 star property	8.8 Excellent 1,000 reviews	View
Tru By Hilton Santee	2.5 star property	9.2 Wonderful 1,017 reviews	View
Baymont by Wyndham Santee	2.5 star property	8.0 Very good 1,513 reviews	View

Other attractions near Santee National Wildlife Refuge

Pine Island

Commune with nature and explore the great outdoors at Pine Island during your travels in Summerton. While you're in the area, wander around the parks.

See properties

Top Santee National Wildlife Refuge Hotel Reviews

Fairfield Inn & Suites by Marriott Santee

Santee

10/10 Excellent

Choose this hotel for a pet-friendly stop-over on our drive to Florida and had a great experience. This staff was super-friendly and this nearly-brand-new property was immaculate. They have us a great 1st floor room with easy access to the walking and parking area. We took advantage of the patio to have dinner (take-out from a local restaurant) and breakfast with our dog. The breakfast was excellent, including hot omelets, eggs, and sausage, and the 6 am start (on a Sunday) allowed us to get...

Douglas

Hampton Inn Santee-I-95

Santee

10/10 Excellent

Michael

Tru By Hilton Santee

Santee

10/10 Excellent

Rebecca

Best Western Plus Santee Inn

Santee

10/10 Excellent

Richard

Holiday Inn Santee by IHG

Santee

10/10 Excellent

Catherine

Baymont by Wyndham Santee

Santee

10/10 Excellent

Angel

Travelodge by Wyndham Santee

Santee

10/10 Excellent

Laurie

A tent with a view of a lake and boats, a wooden chair, and a potted plant.

Bells Marina & Resort

Eutawville

10/10 Excellent

Jack

SureStay Hotel by Best Western Manning

Manning

10/10 Excellent

Coming off I-95 the property is on the left with a narrow entrance sandwiched between a Hampton Inn and a Wendy’s exit. I missed it the first time. I’m not sure whether this is a new property or an old motel that was renovated and rebranded as a Best Western hotel. In any case it is well maintained and attractive. It’s a couple of miles from downtown Manning so eating options are basically fast food. Breakfast buffet was OK. Good value.

Anonymous traveler

Hampton Inn Manning

Manning

10/10 Excellent

Anonymous traveler

Baymont by Wyndham Manning

Manning

10/10 Excellent

Joe

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

Fairfield Inn by Marriott Orangeburg

Orangeburg

10/10 Excellent

Barry

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

Hampton Inn & Suites Orangeburg

Orangeburg

10/10 Excellent

Kevin

A Holiday Inn Express & Suites hotel with a prominent sign, a central entrance, and a symmetrical facade.

Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

10/10 Excellent

Deborah

Frequently Asked Questions

What's the area like around Santee National Wildlife Refuge?

Santee National Wildlife Refuge is located in a welcoming area of Summerton known for its array of dining options and golfing. You'll find 160 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Santee National Wildlife Refuge?

Tru By Hilton Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 4.5 mi (7.2 km) from Santee National Wildlife Refuge. Other good choices within a few miles include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee.

How many hotels will I be able to find near Santee National Wildlife Refuge?

Expedia has 160 hotels and other accommodations a few miles from Santee National Wildlife Refuge.

If I need to cancel the hotel reservation for my stay near Santee National Wildlife Refuge, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review the best deals available near Santee National Wildlife Refuge.

Where can I learn more about changing or cancelling my trip in the area near Santee National Wildlife Refuge?

For more details about updating your stay near Santee National Wildlife Refuge or cancelling it, click here.

Find hotels near Santee National Wildlife Refuge, Summerton from ￥7,750

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Our top choices for Santee National Wildlife Refuge hotels

1. Fairfield Inn & Suites by Marriott Santee

2. Hampton Inn Santee-I-95

3. Best Western Plus Santee Inn

4. Tru By Hilton Santee

5. Baymont by Wyndham Santee

6. Holiday Inn Santee by IHG

7. SureStay Hotel by Best Western Manning

8. Comfort Inn & Suites Santee

9. Travelodge by Wyndham Santee

10. Starlight Stays

11. Super 8 by Wyndham Santee/I-95

12. Hampton Inn Manning

13. Red Roof Inn Santee

14. Quality Inn & Suites Santee I-95

15. Baymont by Wyndham Manning

16. Econo Lodge Santee

17. Best Inn of Manning

18. Sunset Inn Manning I 95

19. Ashburn Inn Manning I 95

20. Clark's Inn

Compare popular hotels close to Santee National Wildlife Refuge

Other attractions near Santee National Wildlife Refuge

Pine Island

Top Santee National Wildlife Refuge Hotel Reviews

Fairfield Inn & Suites by Marriott Santee

10/10 Excellent

Frequently Asked Questions

What's the area like around Santee National Wildlife Refuge?

What's the best place to stay close to Santee National Wildlife Refuge?

How many hotels will I be able to find near Santee National Wildlife Refuge?

If I need to cancel the hotel reservation for my stay near Santee National Wildlife Refuge, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Santee National Wildlife Refuge?