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Check prices for these dates

Next weekend
Jul 24 - Jul 26
In two weeks
Jul 31 - Aug 2

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Our top choices for Santa Maria hotels

Comfort Villa, 3 Bedrooms | Living area

1. NCG SUITE ATARAZANA

NCG SUITE ATARAZANA
2.0 star property
La Atarazana, 6.6 km from Santa Maria
The price is ￥6,236
￥6,236 total
Jul 27 - Jul 28
NCG SUITE ATARAZANA
Deluxe House, 3 Bedrooms, Balcony | Iron/ironing board, WiFi (free)

2. NCG Suite 2

NCG Suite 2
2.0 star property
4.3 km from Santa Maria
The price is ￥3,938
￥3,938 total
Jul 27 - Jul 28
NCG Suite 2
Property entrance

3. DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (643 reviews)
"Nice, clean simple, family run hotel with good transportation."
United States
Gerald
The price is ￥5,846
￥6,008 total
Jul 20 - Jul 21
DC Suites Aeropuerto
Terrace/patio

4. Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.6 out of 10, Excellent, (274 reviews)
"Very clean and comfortable rooms. The staff was very friendly and they're all fluent in English and Spanish. Breakfast in the restaurant was also delicious."
United States
Myna-Maria
The price is ￥9,566
￥11,011 total
Jul 26 - Jul 27
Hotel Puerto Pacifico Guayaquil Airport
Rooftop bar, alfresco dining, open daily

5. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"The room was really clean and the staff in the lobby were really helpful. Breakfast was good"
United States
Rosa
The price is ￥13,008
￥14,796 total
Jul 26 - Jul 27
Wyndham Garden Guayaquil
Cafe

6. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,003 reviews)
"Great overnight stay. Lovely staff, excellent room and amenities and a great breakfast!"
Australia
Peter
The price is ￥14,702
￥16,984 total
Aug 7 - Aug 8
Holiday Inn Guayaquil Airport by IHG
Comfort Double Room | In-room safe, desk, WiFi (free), bed sheets

7. Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 7.3 km from Santa Maria
8.6 out of 10, Excellent, (43 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
The price is ￥5,627
￥5,951 total
Jul 20 - Jul 21
Hotel GH Alexander
Children's activities

8. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,008 reviews)
"Definitely the best and friendliest Hotel in Guayaquil!"
United States
Josef Walter
The price is ￥13,804
￥15,996 total
Aug 8 - Aug 9
Oro Verde Guayaquil
Lobby

9. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (940 reviews)
"Excellent service"
United States
Maritza
The price is ￥9,653
￥11,106 total
Jul 25 - Jul 26
Hotel Palace Guayaquil
Terrace/patio

10. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 4.7 km from Santa Maria
8.2 out of 10, Very Good, (244 reviews)
"Very nice!"
United States
Michael
The price is ￥9,184
￥10,564 total
Jul 23 - Jul 24
Hotel Marcelius
Property entrance

11. Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (705 reviews)
"Good hotel"
United States
juan pablo
The price is ￥14,616
￥16,890 total
Jul 24 - Jul 25
Radisson Hotel Guayaquil
Outdoor pool

12. Tropical Inn

Tropical Inn
2.0 star property
9.2 km from Santa Maria
8.0 out of 10, Very Good, (18 reviews)
"for the price was good"
United States
Rosa
The price is ￥3,800
￥6,236 total
Jul 20 - Jul 21
Tropical Inn
Double Room, 1 Queen Bed, Private Bathroom, Ground Floor | Outdoor pool | Outdoor pool, sun loungers

13. MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 5.1 km from Santa Maria
8.4 out of 10, Very Good, (174 reviews)
"Room was great and very clean. The staff is amazingly friendly and nice. This will be my go to hotel from now on ."
United States
Gary
The price is ￥7,359
￥7,683 total
Jul 27 - Jul 28
MundialCity Hotel Guayaquil
Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers

14. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (1,002 reviews)
"Great place to stay"
United States
Martha Lucia
The price is ￥12,992
￥14,779 total
Aug 13 - Aug 14
Grand Hotel Guayaquil, Centro Histórico.
Down comforters, desk, WiFi (free), bed sheets

15. Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 7.7 km from Santa Maria
8.4 out of 10, Very Good, (120 reviews)
"The breakfast was excellent."
United States
judith
The price is ￥6,314
￥6,638 total
Jul 20 - Jul 21
Hotel Las Peñas
Superior Double Room | Private kitchen | Microwave, electric kettle, griddle, cookware/dishes/utensils

16. Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 5.1 km from Santa Maria
9.4 out of 10, Exceptional, (16 reviews)
"Close to the airport, a little hard to find for taxi or delivery directions but turned out ok. Rooms were clean and had a fridge, range, microwave .. good for a few days to rest and be close to the airport"
United States
Manish
The price is ￥4,148
￥5,448 total
Jul 23 - Jul 24
Suitesecu Rentals Guayaquil
2 bars/lounges, lobby lounge

17. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"Nice river view, clean room, nice staff and breakfast buffet great!!!"
United States
Nancy
The price is ￥16,223
￥18,657 total
Aug 16 - Aug 17
Wyndham Guayaquil Puerto Santa Ana
Reception

18. TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,002 reviews)
"Best place to stay, delicious food and the bed was a dream"
United States
Renata
The price is ￥13,739
￥15,925 total
Aug 16 - Aug 17
TRYP by Wyndham Guayaquil Airport
Indoor pool, open 8:00 AM to 10 PM, sun loungers

19. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 7.9 km from Santa Maria
8.0 out of 10, Very Good, (407 reviews)
"Enjoyed a weekend in Guayaquil. Staff is attentive and genuinely helpful. The hotel is an older property but well-maintained — good price point for the area and what it offers. Breakfast was good. Solid choice for a quiet, relaxed stay in a central location"
United States
Hugo
The price is ￥10,232
￥10,556 total
Jul 20 - Jul 21
Hotel Ramada
Food and drink

20. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 7.5 km from Santa Maria
8.4 out of 10, Very Good, (157 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is ￥7,196
￥7,358 total
Jul 20 - Jul 21
Hotel Patrimonial by Greenfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and El Carmen Hill while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to Alban Borja Commercial Center or San Marino Mall.

Top Santa Maria Hotel Reviews

Oro Verde Guayaquil

Oro Verde Guayaquil

8/10 Good
"Muy buen servicio y muy limpio"
Juan 4-night trip
Posted 6 hours ago
Oro Verde Guayaquil

Frequently asked questions

What is Santa Maria like?
Travelers are sure to enjoy a stay in Guayaquil's Santa Maria neighborhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For more information about changing or cancelling your trip to Santa Maria, go to https://www.expedia.com/service/.
What can I see and do in this Guayaquil neighborhood?
Salón de Eventos Rubi, City Mall, and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.