Default HTG hotel image

Santa Isabel Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Isabel vacation rentals

Fabulous 2-bedroom house with AC in charming Terranova

Fabulous 2-bedroom house with AC in charming Terranova
Terranova
10.0 out of 10, Exceptional, (2 reviews)
"The house was spotless, in a quiet neighborhood, easy excess to main road, and entertainment, great location everything close by."
United States
Francisco
The price is ¥13,116
¥17,273 total
includes taxes & fees
Jul 9 - Jul 10
Fabulous 2-bedroom house with AC in charming Terranova

Sea Breeze Tunnel Hideaway 6

Sea Breeze Tunnel Hideaway 6
3.5 star property
Terranova
8.6 out of 10, Excellent, (8 reviews)
"Great room and location. Nice pool and very clean "
United States
Joel
The price is ¥19,870
¥41,155 total
includes taxes & fees
Jul 23 - Jul 24
Sea Breeze Tunnel Hideaway 6

Ventana al Atlantico at Arecibo 681 Ocean Drive

Ventana al Atlantico at Arecibo 681 Ocean Drive
2.5 star property
Arecibo
7.0 out of 10, Good, (278 reviews)
"It was great just need some improvement "
United States
Richard
The price is ¥17,723
¥24,980 total
includes taxes & fees
Jul 15 - Jul 16
Ventana al Atlantico at Arecibo 681 Ocean Drive

Arecibo Hotel 2104

Arecibo Hotel 2104
3.0 star property
Arecibo
7.0 out of 10, Good, (17 reviews)
"The apartment and bathroom had ants"
United States
Yarlene
The price is ¥14,898
¥22,417 total
includes taxes & fees
Jul 28 - Jul 29
Arecibo Hotel 2104

Colombian Boricua Apartment 5 minutes from the beach luxury

Colombian Boricua Apartment 5 minutes from the beach luxury
Quebradillas
10.0 out of 10, Exceptional, (2 reviews)
"Beautiful "
United States
Vanessa C.
The price is ¥8,195
¥12,021 total
includes taxes & fees
Jul 5 - Jul 6
Colombian Boricua Apartment 5 minutes from the beach luxury

Cozy Isabela Retreat With Garden View

Cozy Isabela Retreat With Garden View
2.0 star property
Isabela
The price is ¥10,324
¥11,253 total
includes taxes & fees
Jul 13 - Jul 14
Cozy Isabela Retreat With Garden View

Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach

Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach
Quebradillas
The price is ¥9,910
¥13,842 total
includes taxes & fees
Jul 8 - Jul 9
Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach

Casa Colibrí

Casa Colibrí
2.5 star property
Arecibo
3.6 out of 10, (11 reviews)
"There is no kitchenette just a dirty fridge; holes in the walls; nothing like those pictures. Did have a bed."
United States
Anthony
The price is ¥12,533
¥25,209 total
includes taxes & fees
Jul 6 - Jul 7
Casa Colibrí

Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
8.8 out of 10, Excellent, (5 reviews)
"Beautiful "
United States
Vanessa C.
The price is ¥10,284
¥19,476 total
includes taxes & fees
Aug 1 - Aug 2
Nature's Lodge Escape

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
Adjuntas
9.6 out of 10, Exceptional, (15 reviews)
"A beautiful home and a great host! Strongly recommend! "
United States
Brandon C.
The price is ¥25,747
¥45,402 total
includes taxes & fees
Jul 13 - Jul 14
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Spacious 3BR Coastal Stay Near Beaches, restaurants and fun

Spacious 3BR Coastal Stay Near Beaches, restaurants and fun
Arecibo
10.0 out of 10, Exceptional, (1 review)
"My family and I stayed here while visiting family in the area. It is a great location, close to the beach, pharmacy, bakery, and convenience store all within walking distance."
United States
Hyomara H.
Spacious 3BR Coastal Stay Near Beaches, restaurants and fun

Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat

Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat
Isabela
10.0 out of 10, Exceptional, (8 reviews)
"Lively place.. very clean. I really enjoyed my stay! Highly recommend.."
United States
Lurdes R.
The price is ¥18,699
¥23,260 total
includes taxes & fees
Jul 12 - Jul 13
Cozy Tiny House for Couples or Families – Peaceful Isabela Retreat

Arecibo Hotel 2105

Arecibo Hotel 2105
2.0 star property
Arecibo
8.4 out of 10, Very Good, (15 reviews)
"The whole process from start to finish was wonderful. The host was wonderful and very resposive."
United States
Alecea
The price is ¥18,292
¥26,142 total
includes taxes & fees
Jul 16 - Jul 17
Arecibo Hotel 2105

The Eden Oasis - A Private Getaway

The Eden Oasis - A Private Getaway
Bajadero
10.0 out of 10, Exceptional, (1 review)
"The home was beautiful and it was close to the beaches and restaurants. We had a wonderful stay and there were several pleasant surprises. The host was very responsive and welcoming!"
United States
Gladys G.
The price is ¥15,447
¥37,991 total
includes taxes & fees
Jul 4 - Jul 5
The Eden Oasis - A Private Getaway

Casita Linda

Casita Linda
2.5 star property
Arecibo
7.8 out of 10, Good, (12 reviews)
"Nice view"
United States
Alexa
The price is ¥21,423
¥32,462 total
includes taxes & fees
Jul 28 - Jul 29
Casita Linda

Cozy Apartment: Wake to Ocean Waves

Cozy Apartment: Wake to Ocean Waves
Hato Abajo
10.0 out of 10, Exceptional, (6 reviews)
"This was a great place to stay. Everything was as described, and we felt comfortable the whole time. The host’s communication was excellent, very responsive, friendly, and made check-in/check-out super easy. Highly recommend!"
United States
Wendelina L.
The price is ¥14,634
¥33,479 total
includes taxes & fees
Jul 8 - Jul 9
Cozy Apartment: Wake to Ocean Waves

Oceanview Apartment with Rooftop

Oceanview Apartment with Rooftop
3.5 star property
Terranova
7.4 out of 10, Good, (3 reviews)
"Excellent "
United States
Jaime
The price is ¥14,648
¥39,006 total
includes taxes & fees
Jul 5 - Jul 6
Oceanview Apartment with Rooftop

VSS La Puntilla Stylish Coastal Getaway Near Beach

VSS La Puntilla Stylish Coastal Getaway Near Beach
Arecibo
The price is ¥13,821
¥29,268 total
includes taxes & fees
Jul 5 - Jul 6
VSS La Puntilla Stylish Coastal Getaway Near Beach

Charming 2-bedroom house in awesome Quebradillas with AC, WiFi

Charming 2-bedroom house in awesome Quebradillas with AC, WiFi
Quebradillas
10.0 out of 10, Exceptional, (1 review)
"yes and yes I some problem finding it, but the was good place and clean"
United States
LUCAS A.
The price is ¥14,634
¥30,382 total
includes taxes & fees
Jul 13 - Jul 14
Charming 2-bedroom house in awesome Quebradillas with AC, WiFi

Cozy 2BR, Terrace, AC & WiFi near Tanama River

Cozy 2BR, Terrace, AC & WiFi near Tanama River
Utuado
10.0 out of 10, Exceptional, (1 review)
The price is ¥22,670
¥48,498 total
includes taxes & fees
Jul 13 - Jul 14
Cozy 2BR, Terrace, AC & WiFi near Tanama River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Isabel Hotel Reviews

Find out more about Santa Isabel

Search for holiday rentals in Santa Isabel on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Isabel using one of the methods below:

  • View our selection of featured holiday rentals in Santa Isabel
  • Use the map to find apartments and other holiday homes in the Santa Isabel neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Isabel while they last

Look no further and take a look at our great range of rental properties in Santa Isabel!

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, we have vacation rentals near top attractions in Santa Isabel, or you can choose a secluded option if you'd like a relaxing place to stay.

What's the top vacation rental that Santa Isabel has to offer?

Villa Melolai - Cerca de Playa Sardinera, Camuy y Arecibo: You might want to consider this vacation home rental near Santa Isabel, which offers an indoor pool, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, an oven, and a microwave, so you can cook with friends or family.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Maricao Fish Hatchery, or get out into nature at a spot like Tanamá River. Parque Ceremonial Indigena Caguana and Guilarte Forest are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned accommodations you can book for a short or long stay in Santa Isabel. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for small groups.