Santa Cruz Vacation Rentals

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Check prices for these dates

Tonight
Dec 9 - Dec 10
Tomorrow
Dec 10 - Dec 11
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Our top choices for Santa Cruz vacation rentals

Classic Loft | Private kitchen | Full-size fridge, microwave, cookware/dishes/utensils
Lofts by Verticca

Lofts by Verticca

3.5 star property
Ojo de Agua
8.2 out of 10, Very Good, (12)
"This was absolutely wonderful they were kind and friendly the loft was very clean and spacious only thing I didn’t like was the tv’s weren’t smart tv’s they only had local cable channels "
United States
Berline
The price is ￥10,869
￥13,043 total
includes taxes & fees
Dec 13 - Dec 14
Lofts by Verticca
Standard Double Suite | City view
UTOPIC Polanco by ULIV

UTOPIC Polanco by ULIV

4.5 star property
Miguel Hidalgo
9.0 out of 10, Wonderful, (725)
"We had a great stay. Area was safe to walk around, and hotel was near tourist attractions. "
United States
Guadalupe
The price is ￥15,468
￥18,484 total
includes taxes & fees
Dec 22 - Dec 23
UTOPIC Polanco by ULIV
Exterior
Casa Chopo

Casa Chopo

3.5 star property
Downtown Mexico City
9.4 out of 10, Exceptional, (101)
"Gorgeous property. "
United States
Jeff
The price is ￥6,662
￥8,061 total
includes taxes & fees
Dec 12 - Dec 13
Casa Chopo
Terrace/patio
The Wild Oscar

The Wild Oscar

4.0 star property
Polanco
9.6 out of 10, Exceptional, (483)
"Don't delay - book the Wild Óscar "
United States
Kasha
The Wild Oscar
Terrace/patio
Las Suites Campos Eliseos

Las Suites Campos Eliseos

4.0 star property
Polanco
9.2 out of 10, Wonderful, (1345)
"The staff was top notch"
United States
Alan
The price is ￥25,171
￥30,079 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Las Suites Campos Eliseos
Indoor spa tub
UTOPIC Platón by ULIV

UTOPIC Platón by ULIV

5.0 star property
Polanco
9.4 out of 10, Exceptional, (124)
"Very clean and safe place."
United States
NIDIA DENICE
The price is ￥19,928
￥23,815 total
includes taxes & fees
Dec 15 - Dec 16
UTOPIC Platón by ULIV
Junior Apartment | Living area | Flat-screen TV
Bright & sweet unit in middle Polanco

Bright & sweet unit in middle Polanco

3.0 star property
Polanco
9.8 out of 10, Exceptional, (43)
"Very cozy and clean. Good walking distance from all types of restaurants."
United States
Lissette
The price is ￥7,861
￥13,406 total
includes taxes & fees
Dec 15 - Dec 16
Bright & sweet unit in middle Polanco
Exterior
ULIV Polanco

ULIV Polanco

3.5 star property
Polanco
8.6 out of 10, Excellent, (106)
"Clean aparrnent. Very polite and helpful staff, especially Teresa"
United States
Galia
The price is ￥39,118
￥46,746 total
includes taxes & fees
Dec 13 - Dec 14
ULIV Polanco
Rooftop terrace
ULIV Apartments Polanco

ULIV Apartments Polanco

4.0 star property
Miguel Hidalgo
8.8 out of 10, Excellent, (298)
"Clean and friendly staff"
United States
Claudia
The price is ￥15,091
￥18,034 total
includes taxes & fees
Dec 14 - Dec 15
ULIV Apartments Polanco
Rooftop terrace
Capitalia Aristoteles Polanco

Capitalia Aristoteles Polanco

4.0 star property
Polanco
9.2 out of 10, Wonderful, (111)
"Great location and a nice apartment "
United States
Luis F
The price is ￥23,836
￥28,842 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Capitalia Aristoteles Polanco
Two-Bedroom Apartment with Huge Private Patio | Terrace/patio
ULIV Parque Lincoln

ULIV Parque Lincoln

3.5 star property
Polanco
9.6 out of 10, Exceptional, (818)
"Staff was great , same as location!"
United States
Ilan
ULIV Parque Lincoln
Hypo-allergenic bedding, in-room safe, individually decorated
Kukun Inspire Polanco

Kukun Inspire Polanco

4.0 star property
Polanco
9.4 out of 10, Exceptional, (206)
"Loved the view from the balcony and very friendly staff. "
United States
Claudia
The price is ￥18,422
￥22,290 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Kukun Inspire Polanco
Front of property
Residence L'heritage Aristóteles 225 by Bluebay

Residence L'heritage Aristóteles 225 by Bluebay

3.0 star property
Polanco
7.2 out of 10, Good, (378)
"Excelente servico"
Mexico
José
The price is ￥13,127
￥15,883 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Residence L'heritage Aristóteles 225 by Bluebay
City view
Casa Sócrates by Kukun

Casa Sócrates by Kukun

2.0 star property
Polanco
8.6 out of 10, Excellent, (146)
"Nice place and good location "
United States
ifeka
Casa Sócrates by Kukun
Apartment, 1 Bedroom | Living area | LCD TV
Nido Parque Lincoln

Nido Parque Lincoln

3.0 star property
Polanco
9.0 out of 10, Wonderful, (197)
"Very nice place to stay "
United States
Virginia
Nido Parque Lincoln
Interior detail
Residence L'heritage Aristóteles 140 by Bluebay

Residence L'heritage Aristóteles 140 by Bluebay

3.5 star property
Polanco
7.4 out of 10, Good, (419)
"Excelente todo "
Mexico
Edith
The price is ￥8,636
￥10,450 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Residence L'heritage Aristóteles 140 by Bluebay
Jr. Penthouse with a Private Terrace | Living area | 50-inch Smart TV with digital channels, Netflix, streaming services
ULIV Park Polanco

ULIV Park Polanco

3.0 star property
Polanco
9.4 out of 10, Exceptional, (86)
"It was a great stay in the perfect location. The space was incredibly clean and the staff were always so helpful and kind! "
United States
Brenda
ULIV Park Polanco
Exterior
ULIV Family Apartments Polanco

ULIV Family Apartments Polanco

4.0 star property
Miguel Hidalgo
9.4 out of 10, Exceptional, (27)
"Excellent location and very secure to walk around. "
United States
Carlos
ULIV Family Apartments Polanco
In-room safe, blackout drapes, free WiFi, bed sheets
Hotel Monaco

Hotel Monaco

3.5 star property
Historic Center
8.0 out of 10, Very Good, (806)
"The staff was exceptionally helpful and kind. I don't think I've ever felt so welcome at a hotel! Our dog was also welcome, which was a relief. "
United States
Chris
The price is ￥7,706
￥9,288 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Monaco
Luxury Apartment, Balcony, City View | Dining room
Capitalia Antara Polanco

Capitalia Antara Polanco

4.5 star property
Polanco
9.2 out of 10, Wonderful, (169)
"Super smooth. Great rooms!!"
United States
Javier
Capitalia Antara Polanco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Capitalia Antara Polanco

Capitalia Antara Polanco

10/10 Excellent
"El senor del front desk es super amable nos sentimos en casa ... felicitacipnes"
Liliana 1-night trip
Posted 1 day ago
Capitalia Antara Polanco

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Polanco Getaway: Outdoor Space & Explore Nearby: This vacation home rental near Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Planetario Luis Enrique Erro, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.