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Check prices for these dates

Tonight
Mar 14 - Mar 15
Tomorrow
Mar 15 - Mar 16
Next weekend
Mar 20 - Mar 22
In two weeks
Mar 27 - Mar 29

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Our top choices for Santa Cruz hotels

Exterior

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
Linda Vista Cabins
Triple Room, 1 King Bed with Sofa bed, Mountain View | Premium bedding, blackout drapes, iron/ironing board, free WiFi

Luxury Canyon Suites

Luxury Canyon Suites
2.0 star property
Alto Boquete
7.2 out of 10, Good, (5 reviews)
"New place, still developing "
United States
Amanda
The price is ￥15,028
￥16,530 total
includes taxes & fees
Mar 21 - Mar 22
Luxury Canyon Suites
Garden views

Hotel Finca Lerida

Hotel Finca Lerida
3.0 star property
Los Naranjos
8.8 out of 10, Excellent, (193 reviews)
"Great place"
United States
Roberto
Hotel Finca Lerida
Premium Cabin | Terrace/patio

Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa
3.0 star property
Cerro Punta
8.8 out of 10, Excellent, (36 reviews)
"Staff were friendly and helpful. Room was okay."
Australia
Michael
Los Quetzales Ecolodge & Spa
Apartment, Garden View, Poolside | Minibar, desk, blackout drapes, free WiFi

Little Italy B&B

Little Italy B&B
3.0 star property
Tijeras
9.4 out of 10, Exceptional, (51 reviews)
"Quiet and clean. Very nice stay!"
United States
patrick
The price is ￥6,372
￥7,009 total
includes taxes & fees
Mar 19 - Mar 20
Little Italy B&B
Spa

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
3.0 star property
Volcan
8.2 out of 10, Very Good, (247 reviews)
"Everything very good, Great staff! Beautiful and relaxing place"
United States
Cristina
The price is ￥15,334
￥16,867 total
includes taxes & fees
Apr 6 - Apr 7
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Deluxe Double Room | Premium bedding, down comforters, in-room safe, desk

Los Brezos Boutique Hotel

Los Brezos Boutique Hotel
3.5 star property
Volcan
9.4 out of 10, Exceptional, (29 reviews)
"Los Brezos is the best hotel in the area. The restaurant is amazing, the food at all times is delicious and high standard"
United States
Damaris
Los Brezos Boutique Hotel
Exterior

Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.
2.0 star property
Nueva California
9.0 out of 10, Wonderful, (9 reviews)
"Hostal Victoria was a simple and down-to-earth Hostal. The entire staff were friendly, kind, and helpful. Good value for a budget place to stay. "
United States
John
Hostal Victoria Volcán Chiriquí S. A.
Exterior

Hotel Dos Rios

Hotel Dos Rios
3.0 star property
Nueva California
8.6 out of 10, Excellent, (80 reviews)
"Beautiful place, we stayed in The junior room it was nice to have the balcony. Very clean "
United States
Silvia
Hotel Dos Rios
Property entrance

Hotel Las Canarias

Hotel Las Canarias
3.0 star property
Paso Canoas
The price is ￥7,024
￥7,748 total
includes taxes & fees
Mar 25 - Mar 26
Hotel Las Canarias
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel Finca Lerida

Hotel Finca Lerida

10/10 Excellent
"Great place"
Roberto 2-night trip
Posted 11 days ago
Hotel Finca Lerida

More cheap stays in Santa Cruz

Luxury Canyon Suites

Luxury Canyon Suites

La Tranca Alto Boquete Provincia de Chiriquí
The price is ￥15,028 per night from Mar 21 to Mar 22
￥15,028
￥16,530 total
Mar 21 - Mar 22
includes taxes & fees
7.2/10 Good! (5 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 12.3 mi (19.8 km) from the heart of Santa Cruz, Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Los Brezos Boutique Hotel and Hotel Finca Lerida. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best vacation home rentals in Santa Cruz?
Casa Little Italy: This vacation home rental outside Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, go to https://www.expedia.com/service/.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 55 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Places to visit in the wider area include Las Cavernas de Corredores, Barriles, and Sitio Barriles Museum. You'll also find Paradise Tropical Garden and Canyon Macho de Monte in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the weather like in Santa Cruz?
The hottest months are usually March and February with an average temp of 78°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa Cruz are October, November, August, and July, with each month seeing an average of 30 inches of rainfall.