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Check prices for these dates

Next weekend
Jun 19 - Jun 21
In two weeks
Jun 26 - Jun 28

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Our top choices for Santa Cruz hotels

Exterior

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (18 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is ￥7,871
￥8,658 total
includes taxes & fees
Jun 22 - Jun 23
Linda Vista Cabins
Triple Room, 1 King Bed with Sofa bed, Mountain View | Premium bedding, blackout drapes, iron/ironing board, free WiFi

Luxury Canyon Suites

Luxury Canyon Suites
2.0 star property
Alto Boquete
7.2 out of 10, Good, (7 reviews)
"New place, still developing "
United States
Amanda
The price is ￥13,526
￥14,878 total
includes taxes & fees
Jun 17 - Jun 18
Luxury Canyon Suites
Dining

Hotel Finca Lerida

Hotel Finca Lerida
3.0 star property
Los Naranjos
8.8 out of 10, Excellent, (202 reviews)
"Great place"
United States
Roberto
The price is ￥28,939
￥31,833 total
includes taxes & fees
Jun 28 - Jun 29
Hotel Finca Lerida
Premium Cabin | Terrace/patio

Los Quetzales Ecolodge & Spa

Los Quetzales Ecolodge & Spa
3.0 star property
Cerro Punta
8.8 out of 10, Excellent, (37 reviews)
"Staff was amazing, local foods excellent. Perfect location for hiking the vertical farms and bird watching!"
United States
David
The price is ￥17,231
￥18,954 total
includes taxes & fees
Jun 17 - Jun 18
Los Quetzales Ecolodge & Spa
Double Room, Garden View | Property grounds

Little Italy B&B

Little Italy B&B
3.0 star property
Tijeras
9.4 out of 10, Exceptional, (53 reviews)
"We loved the breakfast which included fresh fruit. Erick and his wife Jessica couldn’t have been more accommodating. We highly recommend this B&B to anyone coming to the area."
United States
Stephan
The price is ￥6,410
￥7,051 total
includes taxes & fees
Jun 17 - Jun 18
Little Italy B&B
Spa

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
3.0 star property
Volcan
8.2 out of 10, Very Good, (262 reviews)
"nice classy place. with beautiful grounds.."
Canada
Gordon J
The price is ￥18,724
￥20,596 total
includes taxes & fees
Jun 17 - Jun 18
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Deluxe Double Room | Premium bedding, down comforters, in-room safe, desk

Los Brezos Boutique Hotel

Los Brezos Boutique Hotel
3.5 star property
Volcan
9.4 out of 10, Exceptional, (30 reviews)
"Excellent choice for your stay in Volcan. I stayed for 2 nights as solo traveler. Great staff and management. Everyone was helpful and friendly. Volcan is a great base for exploring Cerro Punto region for a day or 2. I highly recommend this hotel. "
United States
Jay
The price is ￥19,037
￥20,941 total
includes taxes & fees
Jun 16 - Jun 17
Los Brezos Boutique Hotel
Exterior

Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.
2.0 star property
Nueva California
9.0 out of 10, Wonderful, (10 reviews)
"Hostal Victoria was a simple and down-to-earth Hostal. The entire staff were friendly, kind, and helpful. Good value for a budget place to stay. "
United States
John
The price is ￥6,490
￥7,211 total
includes taxes & fees
Jun 17 - Jun 18
Hostal Victoria Volcán Chiriquí S. A.
Interior

la casa de Matias

la casa de Matias
2.0 star property
Volcán
The price is ￥7,932
￥8,725 total
includes taxes & fees
Jun 15 - Jun 16
la casa de Matias
Exterior

Hotel Dos Rios

Hotel Dos Rios
3.0 star property
Nueva California
8.6 out of 10, Excellent, (86 reviews)
"Dos Rios provides basic hotel rooms. There is no mini fridge in the room. Rooms were clean, and beds were comfortable. They have beautiful landscaping and flower gardens surrounding the hotel."
United States
Elverne
The price is ￥13,701
￥15,071 total
includes taxes & fees
Jun 20 - Jun 21
Hotel Dos Rios
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel Dos Rios

Hotel Dos Rios

8/10 Good
"Dos Rios provides basic hotel rooms. There is no mini fridge in the room. Rooms were clean, and beds were comfortable. They have beautiful landscaping and flower gardens surrounding the hotel."
Elverne 3-night trip
Posted 11 hours ago
Hotel Dos Rios

More cheap stays in Santa Cruz

Hostal Victoria Volcán Chiriquí S. A.

Hostal Victoria Volcán Chiriquí S. A.

Volcan Chiriquí Nueva California Chiriquí
The price is ￥6,490 per night from Jun 17 to Jun 18
￥6,490
￥7,211 total
Jun 17 - Jun 18
includes taxes & fees
9/10 Wonderful! (10 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 22.8 mi (36.7 km) from the heart of Santa Cruz, Hotel Finca Lerida is a top choice for your stay based on our traveler data. Two other choices for your trip to the area are Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals and Casa Grande Bambito Resort. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best vacation home rentals in Santa Cruz?
Casa Little Italy: This vacation home rental outside Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, go to https://www.expedia.com/service/.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz are sure to find plenty to explore and enjoy. There are 58 hotels and other accommodations in the surrounding area. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Places to visit in the wider area include Las Cavernas de Corredores, Barriles, and Arte Cruz Volcán. You'll also find Paradise Tropical Garden and Canyon Macho de Monte in the area. Check out what more to see and do in Expedia's Santa Cruz guide.
What's the weather like in Santa Cruz?
The hottest months are usually March and February with an average temp of 78°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa Cruz are October, November, August, and July, with each month seeing an average of 30 inches of rainfall.