Default HTG hotel image

Santa Cruz Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Cruz vacation rentals

Linda Vista Cabins

Linda Vista Cabins
3.0 star property
Alto Boquete
9.2 out of 10, Wonderful, (18 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
The price is ¥7,871
¥8,658 total
includes taxes & fees
Jun 22 - Jun 23
Linda Vista Cabins

la casa de Matias

la casa de Matias
2.0 star property
Volcán
The price is ¥7,932
¥8,725 total
includes taxes & fees
Jun 15 - Jun 16
la casa de Matias

Volcano View Cottage

Volcano View Cottage
Volcán
9.6 out of 10, Exceptional, (4 reviews)
"I was alone, but this casita would be perfect for a couple. The owner, Antonio, was quick to respond to any issues. I would definitely stay there again."
United States
John E.
The price is ¥11,217
¥14,422 total
includes taxes & fees
Jun 20 - Jun 21
Volcano View Cottage

Casa Bajareque | Tu escape en Cerro Punta

Casa Bajareque | Tu escape en Cerro Punta
Cerro Punta
The price is ¥35,774
¥40,902 total
includes taxes & fees
Jun 17 - Jun 18
Casa Bajareque | Tu escape en Cerro Punta

Cabañas Mountain View

Cabañas Mountain View
Volcán
The price is ¥16,024
¥20,831 total
includes taxes & fees
Jun 21 - Jun 22
Cabañas Mountain View

Cabin in Cerro Punta 6BR, Fireplace, Hiking

Cabin in Cerro Punta 6BR, Fireplace, Hiking
Cerro Punta
The price is ¥74,704
¥85,440 total
includes taxes & fees
Jun 19 - Jun 20
Cabin in Cerro Punta 6BR, Fireplace, Hiking

Cabañas Mountain View, near to the national park Volcan Baru

Cabañas Mountain View, near to the national park Volcan Baru
Volcán
8.0 out of 10, Very Good, (1 review)
"Basic but nice small cottage which was perfect for relaxing near Volcan."
United States
Paquita B.
The price is ¥11,217
¥16,345 total
includes taxes & fees
Jun 20 - Jun 21
Cabañas Mountain View, near to the national park Volcan Baru
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we give you a choice of vacation rentals near top local attractions in Santa Cruz, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Santa Cruz has to offer?

Casa Little Italy: This vacation home rental outside Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

What’s there to see and do in Santa Cruz?

While you're exploring the area, Las Cavernas de Corredores and Canyon Macho de Monte are a couple of picturesque spots to get outside and enjoy nature. Barriles and Arte Cruz Volcán are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

A vacation rental is a private property you can book for a couple of days or more in Santa Cruz. Vacation rentals provide amenities like kitchens and laundry facilities so you'll have everything you want. If you're concerned about a clean environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a family trip.