Santa Cruz Vacation Rentals

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Check prices for these dates

In two weeks
Mar 20 - Mar 22
In two months
May 1 - May 3
In three months
May 29 - May 31
In four months
Jun 26 - Jun 28

Our top choices for Santa Cruz vacation rentals

Exterior

Cabin in Alto Boquete

Linda Vista Cabins
3.0 star property
9.2 out of 10, Wonderful, (17 reviews)
"Property was the best local accommodation I have had in Panama. The host was outstanding. "
United States
Don
Linda Vista Cabins
Living area

Apartment in Cerro Punta

Cabin in Cerro Punta 6BR, Fireplace, Hiking
The price is ￥72,751
￥81,646 total
includes taxes & fees
Mar 3 - Mar 4
Cabin in Cerro Punta 6BR, Fireplace, Hiking
Terrace/patio

Cottage in Volcán

Volcano View Cottage
9.4 out of 10, Exceptional, (3 reviews)
"I was alone, but this casita would be perfect for a couple. The owner, Antonio, was quick to respond to any issues. I would definitely stay there again."
United States
John E.
The price is ￥9,480
￥12,601 total
includes taxes & fees
Mar 11 - Mar 12
Volcano View Cottage
Property grounds

Cabin in Volcán

Cabañas Mountain View
The price is ￥15,605
￥20,287 total
includes taxes & fees
Mar 4 - Mar 5
Cabañas Mountain View
Interior

Vacation Home in Volcán

Copeyhousechiriquí
The price is ￥7,724
￥12,167 total
includes taxes & fees
Mar 3 - Mar 4
Copeyhousechiriquí
Exterior

Vacation Home in Volcán

Cabañas Mountain View, near to the national park Volcan Baru
8.0 out of 10, Very Good, (1 review)
"Basic but nice small cottage which was perfect for relaxing near Volcan."
United States
Paquita B.
The price is ￥10,924
￥15,918 total
includes taxes & fees
Mar 3 - Mar 4
Cabañas Mountain View, near to the national park Volcan Baru
Property grounds

Apartment in Cerro Punta

Unique eco-cabin inside cloudforest “PILA”
The price is ￥41,353
￥47,283 total
includes taxes & fees
Apr 2 - Apr 3
Unique eco-cabin inside cloudforest “PILA”
Exterior

Apartment in Cerro Punta

Eco-Cabin apartment inside Cloudforest
The price is ￥30,586
￥34,955 total
includes taxes & fees
Apr 2 - Apr 3
Eco-Cabin apartment inside Cloudforest
Exterior

Apartment in Cerro Punta

Cabin inside cloudforest “PILA” floor 1
The price is ￥25,842
￥28,963 total
includes taxes & fees
Mar 3 - Mar 4
Cabin inside cloudforest “PILA” floor 1
Interior

Apartment in Cerro Punta

Cabin inside International Park “PILA”
The price is ￥25,842
￥28,963 total
includes taxes & fees
Mar 3 - Mar 4
Cabin inside International Park “PILA”
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel Finca Lerida

Hotel Finca Lerida

10/10 Excellent
"The room was nice - comfortable and nice service from the coffee served in the morning to the hot water bottle for the bed at night."
Charles 3-night trip
Posted 10 days ago
Hotel Finca Lerida

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
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  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we give you a choice of vacation rentals near top local attractions in Santa Cruz, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Santa Cruz has to offer?

Casa Little Italy: This vacation home rental outside of Santa Cruz offers a balcony, a terrace, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

What’s there to see and do in Santa Cruz?

While you're exploring the area, Las Cavernas de Corredores and Área Silvestre Protegida Lagunas de Volcán are a couple of picturesque spots to get outside and enjoy nature. Barriles and Paradise Tropical Garden are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

A vacation rental is a private property you can book for a couple of days or more in Santa Cruz. Vacation rentals provide amenities like kitchens and laundry facilities so you'll have everything you want. If you're concerned about a clean environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a family trip.