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Check prices for these dates

This weekend
May 29 - May 31
Next weekend
Jun 5 - Jun 7

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Our top choices for Santa Cruz hotels

Outdoor pool

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (378 reviews)
"Very close to the airport Room is so quiet and comfortable "
United States
yong
The price is ￥17,200
￥17,200 total
Jun 3 - Jun 4
Sun Hotel
Outdoor pool, sun loungers

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (138 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is ￥15,879
￥15,879 total
Jun 19 - Jun 20
Hotel Cortez
Seasonal outdoor pool

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (379 reviews)
"Nice hotel"
United States
Mabel Marisel
The price is ￥20,169
￥20,169 total
Jun 12 - Jun 13
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (275 reviews)
"It's good place, with good surroundings."
United States
Christopher
The price is ￥14,890
￥14,890 total
Jun 5 - Jun 6
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Reception

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (426 reviews)
"Good property the great amenities and service"
United States
James
The price is ￥25,111
￥25,111 total
Jun 2 - Jun 3
Camino Real Hotel
Living area

Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
7.8 out of 10, Good, (7 reviews)
"The posada expres was closed and "
United States
Marcelo
The price is ￥6,689
￥7,406 total
May 31 - Jun 1
Posada Express Fast Check
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
United States
Blanca
The price is ￥5,652
￥5,652 total
May 31 - Jun 1
Premium Suites Deluxe Aparthotel Equipetrol
Outdoor pool, pool umbrellas, sun loungers

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (233 reviews)
"Amazing hotel"
United States
Deivis
The price is ￥17,629
￥17,629 total
Jun 5 - Jun 6
Marriott Santa Cruz de la Sierra Hotel
Honeymoon Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (49 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ￥7,339
￥9,728 total
May 30 - May 31
HOTEL OSHO
Exterior detail

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (161 reviews)
"My go too hotel whenever I'm in town! "
United States
Pluetina
The price is ￥15,766
￥15,766 total
May 31 - Jun 1
TRYP by Wyndham Santa Cruz
Double Room, 1 Queen Bed | Premium bedding, down comforters, minibar, blackout drapes

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ￥5,712
￥5,712 total
Jun 27 - Jun 28
Hotel G
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished

Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (131 reviews)
"Everything was excellent! Clean room, delicious food, friendly staff, great location!"
United States
Heidi
The price is ￥11,428
￥11,428 total
Jun 19 - Jun 20
Cosmopolitano Hotel Boutique
Front of property

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (67 reviews)
"Clean room and friendly staff "
United States
marcia
The price is ￥8,600
￥8,600 total
May 31 - Jun 1
Chairú Eco Hotel
Massages

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (87 reviews)
"Beautiful hotel"
Australia
Joanna
The price is ￥23,569
￥23,569 total
Jun 13 - Jun 14
Swissôtel Santa Cruz De La Sierra
Lobby sitting area

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (116 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
The price is ￥16,721
￥16,721 total
Jun 23 - Jun 24
Novotel Santa Cruz De La Sierra
Miscellaneous

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (118 reviews)
"Nice place"
United States
Juan Carlos
The price is ￥9,460
￥9,460 total
May 30 - May 31
Ibis Santa Cruz DE LA Sierra
Exterior

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ￥3,384
￥3,384 total
May 30 - May 31
Surbackpackers
View from property

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.6 out of 10, Excellent, (26 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ￥10,265
￥10,265 total
May 30 - May 31
Hotel Continental Park
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is ￥7,281
￥7,281 total
May 31 - Jun 1
Equipetrol Suites Apart Hotel
Outdoor pool

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (93 reviews)
"Rooms are always spotless good breakfasts rooftop pool with decent view "
Canada
Peter
The price is ￥8,440
￥8,440 total
May 30 - May 31
Delfines Collection Hotel By Mercure
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Vacation Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
Premium Suites Deluxe Aparthotel Equipetrol
See all vacation rentals
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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

4.4/5 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent
"El servicio la localización todo estuvo muy bien además del buen trabajo del personal"
Josue 5-night trip
Posted 21 hours ago
Novotel Santa Cruz De La Sierra

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
The price is ￥7,281 per night from May 31 to Jun 1
￥7,281
￥7,281 total
May 31 - Jun 1

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and free parking. Other good choices for your visit include Sun Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Seasonal House and Jose Luis Noya. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Travelero Hostel ans Tours and Residencial Ikandire II. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guesthouse, and offers an outdoor pool along with in-room kitchens for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and HOTEL OSHO. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza 24 de Septiembre?
Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.
What about the best place to stay near Ventura Mall?
One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the best hotel for staying near Viru Viru International Airport (VVI)?
Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 289 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Cine Center, Sacred Art Museum, and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.