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Find hotels in Santa Ana, Cusco from ¥2,729

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Our top choices for Santa Ana hotels

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1005)
"staff, especially the dine-in restaurant was very helpful and friendly."
Canada
Lorenzo
The price is ¥18,659
¥20,525 total
Dec 21 - Dec 22
Hilton Garden Inn Cusco

Hotel Cusco Pacha Inti

Hotel Cusco Pacha Inti
3.0 star property
Santa Ana
6.0 out of 10, (1)
"El hotel cumple con sus funciones, sin embargo es complicado el tema de la regadera, considero es un punto que pueden mejorar. El hotel no está alejado del centro pero está en una zona no tan cómoda de llegar, ni siquiera los autos tienen accedió tan fácil. El personal es muy atento y amable, sin embargo tuve que pagar dos veces la reservación porque a ellos "no se les reflejaba" siendo que ellos mismos confirmaron que tienen problemas con expedis y Booking y a pesar de que les mostré en mi...
Mexico
CR
The price is ¥4,509
¥4,509 total
Dec 23 - Dec 24
Hotel Cusco Pacha Inti

ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
The price is ¥7,775
¥7,775 total
Dec 13 - Dec 14
ZEVEN HOUSE - CUSCO APARTMENT

Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (12)
"A pleasant place to visit Cuzco"
France
Michel
Centro by Casa Andina Cusco Saphi

Munay Cusco

Munay Cusco
2.0 star property
Santa Ana
The price is ¥2,729
¥2,729 total
Dec 13 - Dec 14
Munay Cusco

Anata Hostel

Anata Hostel
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (22)
"Great location, staff incredible!"
Canada
christiane
The price is ¥3,467
¥3,467 total
Jan 2 - Jan 3, 2026
Anata Hostel

Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (499)
"Great place ! "
United States
Roger
Tierra Viva Cusco Saphi

Santa Ana Departamentos

Santa Ana Departamentos
2.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Grand appartement à 10 min à pied de la place des Armes. Il y a également un bus qui s'arrête devant le portail. Nous sommes toujours descendus à pied et remontés en navette. Eau chaude, appartement un peu froid mais pas insurmontable. Accueil très sympathique et agréable de la part des propriétaires, n'hésitez pas à leur demander conseils ou de l'aide ils feront tout pour vous aider. Nous avons passé un excellent séjour grâce à eux."
France
Mélissa
Santa Ana Departamentos

Hotel Mamasara

Hotel Mamasara
3.0 star property
Santa Ana
8.4 out of 10, Very Good, (18)
"It was nice"
United States
Alexander
Hotel Mamasara

Munay Ñusta Cusco

Munay Ñusta Cusco
3.0 star property
Santa Ana
9.6 out of 10, Exceptional, (4)
"Very nice property"
United States
Arthur
The price is ¥6,997
¥7,697 total
Dec 19 - Dec 20
Munay Ñusta Cusco

Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana
3.0 star property
Santa Ana
The price is ¥4,949
¥4,949 total
Dec 13 - Dec 14
Hotel El Mirador de Santa Ana

Casa Karmenka

Casa Karmenka
2.5 star property
Santa Ana
Casa Karmenka

HOSTAL LA RASA

HOSTAL LA RASA
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (2)
"Accueil très agréable !"
France
Lia
The price is ¥3,079
¥3,079 total
Dec 13 - Dec 14
HOSTAL LA RASA

Tucan Hostel

Tucan Hostel
2.0 star property
Santa Ana
8.4 out of 10, Very Good, (14)
"We found this hostel to be a very special place, filled with wonderfully helpful and pleasant folks. We would highly recommend a stay."
United States
Anonymous traveler
The price is ¥4,820
¥4,820 total
Jan 8 - Jan 9, 2026
Tucan Hostel

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco
4.0 star property
Cusco Historic Center, 0.5 km from Santa Ana
9.4 out of 10, Exceptional, (1100)
"Beautiful room and courtyard. Excellent staff service and food."
Australia
Sage
The price is ¥17,143
¥18,858 total
Jan 12 - Jan 13, 2026
Wyndham Costa del Sol Cusco

LP Los Portales Hotel Cusco

LP Los Portales Hotel Cusco
3.5 star property
Cusco Historic Center, 1.4 km from Santa Ana
9.4 out of 10, Exceptional, (776)
"Located in in the historic district/staff more than helpful/great restaurant/clean room/I recommend without reservation"
United States
Herman Glenn
The price is ¥9,951
¥11,195 total
Jan 4 - Jan 5, 2026
LP Los Portales Hotel Cusco

Sonesta Hotel Cusco

Sonesta Hotel Cusco
4.0 star property
Cusco Historic Center, 1.7 km from Santa Ana
9.6 out of 10, Exceptional, (1005)
"Nice rooms and helpful staff"
Canada
Laura
The price is ¥21,613
¥23,774 total
Dec 13 - Dec 14
Sonesta Hotel Cusco

JW Marriott El Convento Cusco

JW Marriott El Convento Cusco
5.0 star property
Cusco Historic Center, 1.1 km from Santa Ana
9.6 out of 10, Exceptional, (1000)
"We really liked the breakfast and the staffs were very helpful and friendly "
United States
Min
The price is ¥39,183
¥49,476 total
Jan 10 - Jan 11, 2026
JW Marriott El Convento Cusco

Abittare Hotels

Abittare Hotels
3.0 star property
Cusco Historic Center, 1.2 km from Santa Ana
9.0 out of 10, Wonderful, (375)
"Good, clean and nice hotel "
United States
Silvana
The price is ¥10,532
¥11,607 total
Jan 12 - Jan 13, 2026
Abittare Hotels

Novotel Cusco

Novotel Cusco
4.0 star property
Cusco Historic Center, 1.1 km from Santa Ana
9.4 out of 10, Exceptional, (1000)
"Amazing place to stay! "
United States
Giovanna
The price is ¥18,192
¥20,011 total
Jan 9 - Jan 10, 2026
Novotel Cusco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Cusco Historic Center

Explore museums like Museo de Arte Precolombino and savor fusion and neo-Andean cuisine at local restaurants. Stroll through the artisan-filled San Blas neighborhood for a picturesque shopping experience.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Pre-Columbian Art Museum and Plaza de las Nazarenas.

Santiago

When in Santiago, you can plan a visit to Ttio Market and Santiago Plaza, some noteworthy sights in the nearby area.

Santa Monica

Santa Monica might not have many top sights, but Real Plaza Cusco and Ttio Market are two attractions nearby that you can check out.

Top Santa Ana Hotel Reviews

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Frequently asked questions

What is Santa Ana like?
Travelers to Cusco's Santa Ana neighborhood will be sure to enjoy a stay in this neighborhood.
What's the best accommodation in Santa Ana?
Based on Expedia customer reviews, Hilton Garden Inn Cusco is the highest ranked property in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant. Another favorite option in the neighborhood is Hotel Mamasara.
How many hotels should I expect to find in the Santa Ana area?
If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 40 Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, go to https://www.expedia.com/service/.
What can I see and do in this Cusco neighborhood?
A few places to visit in the area around Santa Ana include Museo Irq'i Yachay, Museo de Plantas Sagradas Magicas y Medicinales, and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.