A large military aircraft on a tarmac with a city skyline in the background.

Find Luxury Hotels in Santa Ana, CA

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Ana Luxury Hotels

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Santa Ana luxury hotels

1. Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Santa Ana
  • Newly renovated sanctuary near South Coast Plaza offers outdoor pool luxury and restaurant delights.
¥21,796
¥24,629 total
includes taxes & fees
Oct 2 - Oct 3
Hotel Zessa Orange County Airport, a DoubleTree by Hilton

2. Hyatt Regency Orange County

Hyatt Regency Orange County
Anaheim Resort
  • Opulent OC escape features pillowtop beds, Egyptian cotton sheets, and 2 sparkling outdoor pools.
¥20,242
¥27,402 total
includes taxes & fees
Sep 28 - Sep 29
Hyatt Regency Orange County

3. Costa Mesa Marriott

Costa Mesa Marriott
Costa Mesa
¥19,920
¥22,158 total
includes taxes & fees
Oct 9 - Oct 10
Costa Mesa Marriott

4. The Westin South Coast Plaza, Costa Mesa

The Westin South Coast Plaza, Costa Mesa
Costa Mesa
  • Refined Costa Mesa sanctuary offers pillowtop beds, poolside relaxation, and dining near South Coast Plaza.
¥30,614
¥38,440 total
includes taxes & fees
Oct 2 - Oct 3
The Westin South Coast Plaza, Costa Mesa

5. Hotel Fera Anaheim, a DoubleTree by Hilton

Hotel Fera Anaheim, a DoubleTree by Hilton
Anaheim Resort
  • Modern luxury awaits at this renovated Anaheim hotel with serene pool, gourmet dining, and premium comforts.
¥21,506
¥23,698 total
includes taxes & fees
Oct 26 - Oct 27
Hotel Fera Anaheim, a DoubleTree by Hilton

6. Hilton Orange County/Costa Mesa

Hilton Orange County/Costa Mesa
Sobeca District
  • Poolside luxury awaits at 4-star Costa Mesa hotel with pillowtop beds, designer toiletries, and premium dining.
¥21,796
¥24,236 total
includes taxes & fees
Oct 4 - Oct 5
Hilton Orange County/Costa Mesa

7. Embassy Suites by Hilton Anaheim Orange

Embassy Suites by Hilton Anaheim Orange
Anaheim Resort
  • Dual-pool oasis with luxury suites near Angel Stadium and Downtown Disney in four-star retreat.
¥21,264
¥23,481 total
includes taxes & fees
Oct 25 - Oct 26
Embassy Suites by Hilton Anaheim Orange

8. Avenue of the Arts Costa Mesa, a Tribute Portfolio Hotel

Avenue of the Arts Costa Mesa, a Tribute Portfolio Hotel
Costa Mesa
  • Lakeside luxury thrives at this Costa Mesa retreat with sauna, hot tub, and outdoor pool surrounded by tranquil park paths.
¥29,584
¥32,896 total
includes taxes & fees
Oct 23 - Oct 24
Avenue of the Arts Costa Mesa, a Tribute Portfolio Hotel

9. Ayres Hotel Costa Mesa/Newport Beach

Ayres Hotel Costa Mesa/Newport Beach
Costa Mesa
  • Costa Mesa retreat offers plush comfort with 2 outdoor pools, pillowtop beds with down comforters, and concierge services.
¥22,003
¥24,465 total
includes taxes & fees
Oct 11 - Oct 12
Ayres Hotel Costa Mesa/Newport Beach

10. Irvine Marriott

Irvine Marriott
Airport Area
  • Irvine hotel offers elevated comfort with 2 restaurants, heated outdoor pool, and premium service near UCI.
¥31,952
¥35,154 total
includes taxes & fees
Oct 3 - Oct 4
Irvine Marriott
View all properties

Find out more about Santa Ana

Santa Anaand its attractions for luxury travelers

Santa Ana, California, offers a captivating blend of culture and luxury that travelers will appreciate. Start your exploration at the Bowers Museum, where exquisite exhibits showcase Native American art and California history, providing a rich cultural backdrop to your stay. For art enthusiasts, the nearby Orange County Museum of Art features contemporary works that will spark inspiration and conversation. Enjoy a leisurely afternoon at the serene Centennial Park, perfect for a family picnic or a tranquil stroll amidst lush landscapes. If you're seeking shopping and dining, the South Coast Plaza is a must-visit, high-end retailers like Chanel and Gucci, alongside gourmet dining options that will satisfy your culinary cravings. Finally, indulge in a performance at the Segerstrom Center for the Arts, where world-class theatre and music events await. For a luxurious stay, consider the hotels in the South Coast area, where you can enjoy opulent amenities, attentive service, and easy access to these attractions—all while feeling pampered in a vibrant atmosphere.

Find the best luxury hotels and resorts in Santa Ana

For travelers seeking an upscale experience in Santa Ana, California, these luxury hotels provide exceptional amenities and service that cater to travelers.Hotel Zessa Orange County Airport, a DoubleTree by Hilton

  • Why it's great for a luxury retreat: Hotel Zessa Orange County Airport is an excellent choice for luxury seekers, a popular guest review rating of 8.2. This elegant hotel features designer toiletries and premium bedding, ensuring a plush stay for guests. The on-site concierge is available to assist with arrangements, enhancing the overall experience with personalized service and local insights.
  • Other amenities: Guests can enjoy a relaxing outdoor pool and hot tub, perfect for unwinding after a day of travel. The hotel is conveniently located within a shopping district, allowing guests to indulge in retail therapy right at their doorstep. Additional features include contactless check-in for a seamless arrival experience, accessible parking options, and daily housekeeping to maintain comfort. For those needing to stay connected, the hotel offers fitness facilities nearby and complimentary toiletries to elevate the luxury experience.
  • Nearby attractions: South Coast Plaza - 1.98 miles, Segerstrom Center for the Arts - 1.8 miles, The Observatory - 3.24 miles

Top Santa Ana Hotel Reviews

Clementine Hotel & Suites Anaheim

Clementine Hotel & Suites Anaheim

10/10 Excellent
"Perfect location for Disney, clean spacious rooms and overall a great place for families to stay!"
Adam 4-night trip
Posted less than an hour ago
Clementine Hotel & Suites Anaheim
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

10/10 Excellent
"This is my second stay here. I love the layout of the rooms. We are always very comfortable here. I find the hotel grounds to also be. Dry cute. Loff the pool and hot tub. The only complaint is the parking lot. It seems super cramped driving in and out. There’s a lot of big cars parked there and sometimes it’s a squeeze. Otherwise the stay is always good and the price seems right"
Judy 2-night trip
Posted less than an hour ago
MainStay Suites John Wayne Airport by Choice Hotels
Motel 6 Anaheim Maingate

Motel 6 Anaheim Maingate

10/10 Excellent
"It was a 15min walk to Disneyland! And clean! Take them kids to Disney and not go over budget!"
Sameria 3-night trip
Posted 1 hour ago
Motel 6 Anaheim Maingate
The Maya

The Maya

10/10 Excellent
"."
Michelle 1-night trip
Posted 1 hour ago
The Maya
Hyatt Regency Orange County

Hyatt Regency Orange County

10/10 Excellent
"Big facility with easy loading and unloading in the front. Only complaint was room floor was dirty."
Britaney 1-night trip
Posted 3 hours ago
Hyatt Regency Orange County
Grand Legacy At the Park

Grand Legacy At the Park

10/10 Excellent
"Amazing stay!!"
Justin 4-night trip
Posted 4 hours ago
Grand Legacy At the Park
Embassy Suites by Hilton Anaheim South

Embassy Suites by Hilton Anaheim South

10/10 Excellent
"The hotel is beautiful, and conveniently located near almost everything in Anaheim. The room itself was beautiful, very clean, and plenty of space for 2. The free breakfast was a hit, everything was very fresh and tasty, and the staff was always very helpful. If I visit Anaheim again, I will certainly stay here!"
Robert 3-night trip
Posted 8 hours ago
Embassy Suites by Hilton Anaheim South
Knott's Hotel

Knott's Hotel

10/10 Excellent
"This is always our place to go anytime we come down for Scary Farm. Staff is super professional and nice, rooms are clean and it’s right next to the park!"
Akisa 2-night trip
Posted 18 hours ago
Knott's Hotel
Best Western Plus Stovall's Inn

Best Western Plus Stovall's Inn

8/10 Good
"Everything about the hotel is great. I downgraded to four stars only because after staying there for a number of years, I’ve noticed that it’s starting to look a bit tired. I hope they plan a refresh of the property sooner rather than later. Lighter room colors, no carpet, more outlets for chargers. However, I will continue to stay there due to the location, cleanliness, breakfast, and friendly staff."
Nicole 3-night trip
Posted 23 hours ago
Best Western Plus Stovall's Inn

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Santa Ana?
Use Expedia to arrange your flight to John Wayne Airport (SNA) airport or Fullerton, CA (FUL-Fullerton Municipal) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Santa Ana has to offer. During your visit, you might want to enjoy the beaches and shopping which Santa Ana is known for.
When can I expect good weather in Santa Ana?
Planning for the weather is an important factor for making your trip to Santa Ana a success, especially when you're splurging. The hottest months are usually August and September with an average temp of 74°F, while the coldest months are February and January with an average of 58°F. Average annual precipitation for Santa Ana is 12 inches.
What's there to see and do in Santa Ana?
Take in some sights and attractions while you're in Santa Ana by visiting Old Orange County Courthouse, Bowers Museum, and Santa Ana Zoo. If you have a little extra time during your trip, you might want to make a stop at Heritage Museum of Orange County and The Observatory.
How can I get around Santa Ana?
It's easier to get around town in style when you know your options. To see more of the larger area, hop aboard a train at Santa Ana Regional Transportation Center.

Explore a world of travel with Expedia