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Check prices for these dates

This weekend
May 29 - May 31
Next weekend
Jun 5 - Jun 7

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Our top choices for San Francisco hotels

Outdoor pool

HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.4 out of 10, Exceptional, (113 reviews)
"Great place to stay, quiet…"
United States
Eduardo
The price is ￥11,064
￥12,280 total
includes taxes & fees
Jun 12 - Jun 13
HOTEL VISTA LAGO
Interior

Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
3.0 star property
Nuevo Santiago
9.6 out of 10, Exceptional, (5 reviews)
"This super convenient hotel was a delight and a surprise. Very clean updated and right off the Pan American Highway. Excellent room and the industrial scale but home cooked goodness of the fonda downstairs just perfect. We will 100% plan on staying here every trip."
Canada
Philip
The price is ￥8,239
￥9,063 total
includes taxes & fees
Jun 12 - Jun 13
Hotel Plaza Los Tucanes
Outdoor pool, free cabanas, pool umbrellas

Hotel Gran David

Hotel Gran David
3.5 star property
Santiago
8.6 out of 10, Excellent, (404 reviews)
"Good hotel, good service and good breakfast"
Mexico
Kayser
The price is ￥11,064
￥12,280 total
includes taxes & fees
May 28 - May 29
Hotel Gran David
3 outdoor pools, free cabanas, pool umbrellas

Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (580 reviews)
"Very nice property and an excellent room "
United States
Larry
The price is ￥12,714
￥13,985 total
includes taxes & fees
Jun 9 - Jun 10
Hotel Mykonos Panama
Restaurant

Hotel Anachoreo

Hotel Anachoreo
3.0 star property
Santa Fe
9.6 out of 10, Exceptional, (43 reviews)
"Great stay"
United States
John
The price is ￥13,438
￥14,783 total
includes taxes & fees
Jun 1 - Jun 2
Hotel Anachoreo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Francisco Hotel Reviews

Hotel Mykonos Panama

Hotel Mykonos Panama

6/10 Okay
"My room’s AC did not work properly. Maintenance had to come in at 5am as I could no longer bare the heat. Maintenance said the AC was fine when standing in a certain location. That was upsetting when the whole room should be cool. Front desk staff of morning shift said why haven’t we complained earlier…..???? We complained at 5am and they were going to change our room at that time and front desk overnight shift did not contact us. They definitely recognized that the AC unit was not working when they contacted us saying a new room will be waiting for us. Housekeeping does not knock and announce themselves!!!! Big issue!!!!!! Breakfast was good - however sucks that they didn’t allow us to bring breakfast back to the room as we wanted to have breakfast in bed. Sad to see the hotel not be like it was years ago."
Ailyn 2-night trip
Posted 1 day ago
Hotel Mykonos Panama

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Frequently asked questions

What's the best place for a stay in San Francisco?
Hotel Mykonos Panama, located 10.4 mi (16.8 km) from the heart of San Francisco, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.
What are some of the best vacation rentals that San Francisco has to offer?
Cabana Vergara Santa Fe: This vacation home rental outside of San Francisco offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and kitchenware. See all vacation rentals in San Francisco.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
To find more details about picking new dates or cancelling your trip to San Francisco, click here.
What is staying in San Francisco like?
Visitors to San Francisco are sure to find plenty to explore and enjoy. There are 19 hotels and other accommodations in the surrounding area. Find out more about San Francisco.
What should I see while I'm in San Francisco?
Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Laguna de La Yeguada, and Catedral of Santiago Apostol. You'll also find Los Pozos Termales and Omar Torrijos Herrera Stadium in the area. Check out what more to see and do in Expedia's San Francisco guide.
What's the weather like in San Francisco?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in San Francisco are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.