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Top San Antonio Luxury Hotels

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (589)
"This property is
luxury
and comfort. Friendly staff, great but expensive sunday brunch and breakfast buffet. Highly recommend it to pamper yourself"
Amelia
The price is ¥30,102
¥33,112 total
includes taxes & fees
Aug 1 - Aug 2
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

W Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"I had an amazing experience at the W Panama! From the moment I arrived, the staff was warm, welcoming, and attentive to every detail. The room was spotless, beautifully designed, and incredibly comfortable. The amenities, from the pool to the restaurant, exceeded my expectations. The location was perfect, making it easy to explore the area. I truly appreciated the outstanding customer service and can’t wait to return. Highly recommend for anyone looking for a
luxurious
and
relaxing
stay! "
Aleaha
The price is ¥28,189
¥31,008 total
includes taxes & fees
Aug 1 - Aug 2
W Panama

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1014)
"I stayed at the JW Marriott Panama hotel for 7 nights and it was an awesome experience. The highlight for me was the staff. They always greet you with a smile and so helpful. The property is well maintained and clean. I highly recommend this hotel if you are looking for that
luxury
experience and relaxation. The
ocean view
from the infinite pool is amazing."
Charmaine Marie
The price is ¥29,950
¥32,945 total
includes taxes & fees
Jul 25 - Jul 26
JW Marriott Panama

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1010)
"Pool was great"
Gerard Nigel
The price is ¥22,704
¥24,975 total
includes taxes & fees
Aug 1 - Aug 2
The Westin Playa Bonita Panama

Sofitel Legend Casco Viejo, Panama City

5.0 star property
9.8 out of 10, Exceptional, (475)
"We stayed at Sofitel Legend Casco Viejo for the final leg of our honeymoon, and it was truly the best experience of our lives. From the moment we arrived, the staff went above and beyond to make our stay unforgettable, with thoughtful touches and gifts celebrating our honeymoon. The butler service for our suite was one of the highlights, especially the
romantic
bath preparations and the flawless turndown service. It felt like every detail was taken care of with such care and elegance. The hotel...
Meryl
The price is ¥43,123
¥47,435 total
includes taxes & fees
Jul 16 - Jul 17
Sofitel Legend Casco Viejo, Panama City

Waldorf Astoria Panama

5.0 star property
9.0 out of 10, Wonderful, (1002)
"From the moment we arrived at the Waldorf Astoria Panama, we were treated to an experience that went beyond our highest expectations. The hotel itself boasts impeccable facilities, blending
luxury
with the warmth of Panamanian hospitality, but what truly set our stay apart was the outstanding concierge service provided by Lille Marie. Lille Marie was a treasure trove of local knowledge, guiding us through Panama’s vast array of attractions with recommendations that felt tailor-made for our...
Alicia
The price is ¥31,712
¥34,883 total
includes taxes & fees
Jul 26 - Jul 27
Waldorf Astoria Panama

Hilton Panama

5.0 star property
8.8 out of 10, Excellent, (1004)
"The hotel was very nice, clean and
luxurious
. There were Christmas celebrations going on at ground level and we heard nothing from our room. Beautiful hotel. "
Peter
The price is ¥28,697
¥31,567 total
includes taxes & fees
Aug 1 - Aug 2
Hilton Panama

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 out of 10, Wonderful, (1002)
"This is the place to come if you are looking for a comfortable, quiet,
relaxing
and high end stay. The service of this property was top notch. It is a refined hotel with a laid-back yet
luxurious
environment. The staff is very attentive and very nice and they made me feel like I was at home. I appreciated the fact that they remembered me and greeted me by name whenever I walked through the lobby. They have the best curated music selection too! I can't say enough about the wonderful restaurant...
Kimberly
The price is ¥26,942
¥29,636 total
includes taxes & fees
Aug 1 - Aug 2
Bristol Panama, a Registry Collection Hotel

Renaissance Panama City Hotel

5.0 star property
8.8 out of 10, Excellent, (28)
"Everything was nice clean friendly staff"
Reno Gracia
The price is ¥15,185
¥16,703 total
includes taxes & fees
Jul 25 - Jul 26
Renaissance Panama City Hotel

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4098)
"Good atmosphere, pool is fun, great drinks "
scott
The price is ¥16,954
¥18,649 total
includes taxes & fees
Jul 29 - Jul 30
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to San Antonio?
Expedia can help you get a flight to Tocumen Intl. Airport (PTY) airport or Panama City (PAC-Marcos A. Gelabert Intl.) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay special. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that San Antonio has to offer.
What's the best time to vacation in San Antonio?
The hottest months are usually March and April with an average temperature of 80°F,
  • Coldest months: January, February, March, and November
  • Driest months: February, March, January, and April
  • Rainiest months: July, August, June, and May
What's there to see and do in San Antonio?
Enjoy all that San Antonio has to offer when you visit Albrook Shopping Mall, Metromall Panama, and Los Pueblos Commercial Center. If you have a little extra time during your trip, you might want to make a stop at Estadio Rommel Fernandez and Panama Viejo.