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Find hotels in San Antonio, Cali

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Our top choices for San Antonio hotels

Casa Ruta Sur

Casa Ruta Sur
3.0 star property
San Antonio
9.8 out of 10, Exceptional, (30)
"Loved the neighborhood that this property was in. It was so pretty with lots and lots of great restaurants nearby and pretty safe. The property itself was also beautiful "
United States
Toni
The price is ¥9,854
¥9,854 total
Jan 24 - Jan 25, 2026
Casa Ruta Sur

Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
10.0 out of 10, Exceptional, (3)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is ¥4,969
¥4,969 total
Jan 8 - Jan 9, 2026
Hotel Casa Bresse

Magic Garden House

Magic Garden House
3.0 star property
San Antonio
10.0 out of 10, Exceptional, (35)
"Very nice accommodation, great service and good location"
Germany
Klemens
Magic Garden House

San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (64)
"The staff was great. "
United States
Victor
The price is ¥8,466
¥10,950 total
Jan 8 - Jan 9, 2026
San Antonio Hotel Boutique

Santiago DC Hotel

Santiago DC Hotel
3.0 star property
San Antonio
8.0 out of 10, Very Good, (2)
"The staff is very courteous. The breakfast is simple but delicious . The room was clean, spacious and with excellent AC. The only thing to consider is that there is a very cannabis friendly bar downstairs in the lobby area and you walk through it to get to your room. The rooms do not smell of cannabis but you walk through a lot of it. "
United States
Eva
The price is ¥7,747
¥23,359 total
Jan 16 - Jan 17, 2026
Santiago DC Hotel

Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (200)
"Rooms are spacious and beautifully designed."
United States
Mark
The price is ¥15,553
¥15,553 total
Jan 13 - Jan 14, 2026
Alko Hotel Casa Nispero

casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
The price is ¥3,122
¥3,746 total
Jan 4 - Jan 5, 2026
casa hostal ave maria san antonio cali

Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is ¥2,921
¥2,921 total
Jan 5 - Jan 6, 2026
Epifania Guest House

La posada del ceramista

La posada del ceramista
3.0 star property
San Antonio
The price is ¥5,652
¥5,652 total
Dec 25 - Dec 26
La posada del ceramista

Osve Hotel Boutique

Osve Hotel Boutique
4.0 star property
1.3 km from San Antonio
10.0 out of 10, Exceptional, (2)
"Everything was good. The room, breakfast, the swimming pool..."
Belgium
Katia
The price is ¥14,575
¥14,575 total
Jan 8 - Jan 9, 2026
Osve Hotel Boutique

hotel terraza San Antonio

hotel terraza San Antonio
3.0 star property
0.2 km from San Antonio
10.0 out of 10, Exceptional, (4)
"Staff was very friendly and helpful. Room was very clean and hotel had great character "
United States
kurt
The price is ¥5,217
¥5,217 total
Jan 8 - Jan 9, 2026
hotel terraza San Antonio

Hotel Alameda Plaza

Hotel Alameda Plaza
2.5 star property
1.4 km from San Antonio
9.8 out of 10, Exceptional, (8)
"Hotel stay was amazing.. Great location and hotel fit my needs.. Hotel is very clean and staff is extremely accommodating and helpful. Great amenity of a daily continental breakfast. "
United States
Joseph
The price is ¥6,498
¥9,355 total
Jan 8 - Jan 9, 2026
Hotel Alameda Plaza

RECOVERY HOUSE BY ZENYA HOST

RECOVERY HOUSE BY ZENYA HOST
3.0 star property
2.5 km from San Antonio
8.4 out of 10, Very Good, (5)
"Address does not exist. SCAM"
United States
Jorge
The price is ¥5,683
¥5,683 total
Dec 25 - Dec 26
RECOVERY HOUSE BY ZENYA HOST

Hotel Karlo

Hotel Karlo
3.0 star property
Viejo San Fernando, 1.5 km from San Antonio
7.8 out of 10, Good, (49)
"Thank you all for your wonderful hospitality. See you again"
United States
Julia
Hotel Karlo

Torca Hotel

Torca Hotel
3.5 star property
Nuevo San Fernando, 2 km from San Antonio
8.4 out of 10, Very Good, (46)
"Great hotel "
United States
Andy
The price is ¥9,480
¥9,480 total
Jan 24 - Jan 25, 2026
Torca Hotel

Hotel Imbanaco

Hotel Imbanaco
3.0 star property
2.8 km from San Antonio
7.6 out of 10, Good, (97)
"Amazing all the staff!! Good place! But please eveday change the breakfast ty"
United States
Yolanda
The price is ¥6,202
¥6,202 total
Jan 24 - Jan 25, 2026
Hotel Imbanaco

HGO HOTEL

HGO HOTEL
3.0 star property
2.9 km from San Antonio
8.4 out of 10, Very Good, (9)
"Wonderful, bright, clean with a great breakfast. "
United States
Angela
The price is ¥12,029
¥12,029 total
Jan 11 - Jan 12, 2026
HGO HOTEL

Hotel Casa Kreenty

Hotel Casa Kreenty
3.0 star property
Viejo San Fernando, 1.3 km from San Antonio
The price is ¥7,825
¥9,067 total
Dec 25 - Dec 26
Hotel Casa Kreenty

Hotel Brisas de Calima

Hotel Brisas de Calima
2.5 star property
6.1 km from San Antonio
8.2 out of 10, Very Good, (38)
"Pretty good location, safe area, plenty of options for shopping, and eat. The staff are so wekconming and professional"
United States
Ingrid
The price is ¥4,509
¥4,509 total
Dec 25 - Dec 26
Hotel Brisas de Calima

Mirago Hotel

Mirago Hotel
2.5 star property
6 km from San Antonio
10.0 out of 10, Exceptional, (1)
"Excelente todo!"
Colombia
Michael
The price is ¥7,221
¥7,221 total
Jan 23 - Jan 24, 2026
Mirago Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

El Peñon

When in El Peñon, you can plan a visit to Centenario Commercial Center and Rock Park, some noteworthy sights in the nearby area.

Rozo

Check out nearby sights like Fenix Air Museum while you're spending some time in Rozo and the surrounding area.

Top San Antonio Hotel Reviews

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on Expedia customer reviews, Alko Hotel Casa Nispero is the highest ranked property in San Antonio. This hotel offers free breakfast and a restaurant. Another favorite option in the neighborhood is Viajero Cali Hostel & Salsa School.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 44 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Religious Art Museum, Enrique Buenaventura Municipal Theater, and La Merced Archaeological Museum are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Calima Gold Museum of the Bank of the Republic and Comfandi and Comfenalco Cultural Center are a couple of additional sights to visit in Cali.