Take advantage of a free breakfast buffet, a gym, and a 24-hour business center at Comfort Inn and Suites Near Medical Center. For some rest and relaxation, visit the hot tub. Stay connected with free in-room WiFi.
Located in San Antonio, Comfort Inn and Suites Near Medical Center is near the airport and near a metro station. North Star Mall and Market Square are worth checking out if shopping is on the agenda, while those wishing to experience the area's popular attractions can visit San Antonio Zoo and Aquarium and Six Flags Fiesta Texas. Looking to enjoy an event or a game? See what's going on at Alamodome or Frost Bank Center. Visit our San Antonio travel guide
78201, TX, San Antonio, 6039 IH 10 West, Exit #565B-Vance Jackson Rd
What's nearby
River Walk
9 min drive - 11.3 km
Henry B. González Convention Center
11 min drive - 12.8 km
Six Flags Fiesta Texas
13 min drive - 19.9 km
Lackland Air Force Base
13 min drive - 23.2 km
Wonderland of the Americas Mall
2 min drive - 2.3 km
Getting around
San Antonio Station
16 min drive
San Antonio International Airport (SAT)
9 min drive
Restaurants
Circle K
15 min walk
McDonald's
16 min walk
Taquitos West Avenue
14 min walk
Bill Miller Bar-B-Q
2 min walk
Pizza Patron
15 min walk
About this property
Comfort Inn and Suites Near Medical Center
Hotel near River Walk
A free breakfast buffet, a gym, and a 24-hour business center are just a few of the amenities provided at Comfort Inn and Suites Near Medical Center. For some rest and relaxation, visit the hot tub. Stay connected with free in-room WiFi.
Other perks include:
2 indoor pools
Free self parking
Express check-out, a 24-hour front desk, and a gift shop
A vending machine, smoke-free premises, and a computer station
Guest reviews speak highly of the helpful staff
Room features
All 82 rooms feature comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and free newspapers. Guest reviews speak well of the clean rooms at the property.
More conveniences in all rooms include:
Bathrooms with rainfall showers and shower/tub combinations
43-inch LED TVs with premium channels
Refrigerators, microwaves, and freezers
Similar properties
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Does Comfort Inn and Suites Near Medical Center have a pool?
Yes, this property has 2 Indoor pools. Pool access is from 10:00 AM–10:00 PM.
How much does it cost to stay at Comfort Inn and Suites Near Medical Center?
As of Oct 23, 2026, prices found for a 1-night stay for 2 adults at Comfort Inn and Suites Near Medical Center on Nov 15, 2026 start from ¥8,272, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
Is Comfort Inn and Suites Near Medical Center pet-friendly?
No, only service animals are welcome at the property.
How much is parking?
Self parking is free at this property.
What time is check-in at Comfort Inn and Suites Near Medical Center?
Check-in start time: 3 PM; Check-in end time: midnight. After-hours check-in is not available.
What time is check-out at Comfort Inn and Suites Near Medical Center?
Check-out is at 11 AM.
Where is Comfort Inn and Suites Near Medical Center located?
Situated near the airport, this hotel is 1.2 mi (2 km) from Wonderland of the Americas Mall and within 3 mi (5 km) of Methodist Hospital Texsan and Woodlawn Theater. River Walk and Alamo are also within 6 mi (10 km).
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Comfort Inn and Suites Near Medical Center Reviews
7.2
Good
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
The beds were very comfortable. The air conditioner kept the room. It has an indoor swimming pool and hot tub. The breakfast was good with many different items to choose. The staff was friendly and helpful.
I am a gold member on Expedia so we got upgraded to the king suite we also had 20 dollars worth of vouchers for the bar which was nice and I really loved the shampoo and body wash they have it smells relaxing. They also leave a robe for you in the bathroom.
I posted this hotel on TikTok since I liked it so much and I do travel content
Stayed 1 night in Sep 2026
Verified review
8/10 Good
Steve
Sep 17, 2026
Liked: Cleanliness, staff & service, amenities
Clean and comfortable at a great rate, the only problem is the bathrooms in the lobby have been out of order for over a month (they wet closed the last time we stayed there).
The hot tub is really nice. There is an indoor pool. The room was clean. Check-in was quick.
Stayed 2 nights in Aug 2026
Verified review
8/10 Good
Nicole
Oct 15, 2026
Liked: Cleanliness, staff & service
Disliked: Amenities
The room was clean. The bed was comfortable. The fridge & freezer worked well. They was a coffee machine & microwave but we didn't use them.
The hot tub had no controls and was barely warm and the water in both the pool and the hot tub were light green, not well maintained or cleaned.
The breakfast was decent, eggs, sausage, bread, cereal, waffles and juice & coffee.
Staff were very polite and helpful.
Location was good as you have an IHOP right next door and a chicken place called Bill Miller, just a walk across the parking lot.
Our room was very comfortable and all of the amenities were great, however the room could have had a little maintenance done (toilet seat was falling off when we arrived) other than that everything was fine.
The stay was alright the blanket had makeup on it still and the A/C had mold in it. The breakfast food was good though.
Stayed 1 night in Aug 2026
Verified review
6/10 Okay
Sajan
Sep 13, 2026
The rooms were spacious however, there are no vending machines. There is one area by the reception where some snacks and water and drinks are available, however you have to pay cash and $5 per water bottle and soda was quite a bit much. Overall experience was average, nothing in terms of service or amenities stood out.
The staff was very accommodating when it came to really early check-in as Jay at the front desk was very professional and kind when i checked in, tbe room was very spacious and provided all commodities id need for my stay.
Stayed 5 nights in May 2026
Verified review
8/10 Good
Donneisha
Sep 16, 2026
Liked: Cleanliness, staff & service
Pros: My room was simple but clean and the ac was on when I arrived. I stayed on the 3rd floor and it was quiet. The bed was also pretty comfy. I had no issue with parking. Staff were friendly. Came by in am for cleaning but I denied, everything was stocked. Check in/checkout was easy. Free breakfast, but limited options.
Cons: Hot breakfast was the same, it didn’t change.(eggs and sausage) Elevator needs some work. The light was flashing and there were scratches. It was also missing the up/down light sign. I didn’t need it, but the washer was broken.
Stayed 2 nights in Sep 2026
Verified review
10/10 Excellent
Ann Mayca
Jun 11, 2026
Liked: Cleanliness, staff & service, amenities
we stayed with 4 kids. the room was clean and they clean it everyday. my kids enjoyed the indoor pool and the breakfast were great. aporoachable staff.
Cleaning staff one girl was excellent but the first
Stayed 5 nights in Jun 2026
Verified review
8/10 Good
Julie
Sep 11, 2026
Liked: Cleanliness, staff & service
Disliked: Amenities
The staff was very friendly and accommodating, however the cable was not very great, no on demand or access to anything but a guide and whatever is on at the time. The WiFi code also did not work.I used the workout room one night but the treadmill did not work and it was 80* in there with no fan. Our toilet did not flush and we had to get a plunger from downstairs. Just little things, we had to leave very early each morning before the continental breakfast but they did have drinks and snacks to purchase downstairs. Also a wal mart was right next door as well as a Dominoes for a quick easy dinner. We were in town for Air Force graduation and it was a super friendly and clean hotel to sleep in. If you go out at night and don’t care about cable or want to work out I highly recommend this spot.
The room has this indescribable odor. Almost certain it’s in the carpet. The chair had stains just as other reviews mentioned.
I didn’t feel unsafe. Parking lot is well lit. Limited access into the building. Night staff was very alert when we arrived in the middle of the night.
The staff were accommodating and professional. The gym is simple and clean. Nearby is a mall, some shopping centers, a Target and a Walmart, restaurants, Dave & Buster and Six Flags. The stay satisfied what we needed for the one night but we won’t be back.