An aerial view of a historic city center with terracotta-roofed buildings, a prominent red-brick structure, and modern high-rises in the background.

Find hotels in San Antonio, Cali

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for San Antonio hotels

Reception

1. San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (69 reviews)
"The location was excellent, within close distance to many good restaurants. The breakfast was good, with fruit and made to order eggs. The AC was quite adequate. "
United States
Jung
The price is ￥12,314
￥12,314 total
Oct 3 - Oct 4
San Antonio Hotel Boutique
Exterior

2. Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (243 reviews)
"Everybody just made us feel at home ! They offered us a free room upgrade which made us even more wowed at the property! Stunning! Will definitely return !"
United States
Catherine
The price is ￥23,027
￥23,027 total
Oct 4 - Oct 5
Alko Hotel Casa Nispero
Junior Double Room, Balcony, City View | Exterior

3. Hotel habitat san antonio

Hotel habitat san antonio
San Antonio
The price is ￥6,999
￥6,999 total
Sep 22 - Sep 23
Hotel habitat san antonio
Standard Single Room | Living area

4. Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
9.2 out of 10, Wonderful, (5 reviews)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is ￥7,587
￥7,587 total
Sep 27 - Sep 28
Hotel Casa Bresse
Restaurant

5. Viajero Cali Hostel & Salsa School

Viajero Cali Hostel & Salsa School
2.0 star property
San Antonio
9.0 out of 10, Wonderful, (68 reviews)
"Excellent stay. I stayed in a private room which was small, basic but comfortable. The staff were friendly. The hostel is in a excellent location close to restaurants, bars and attractions. The extra activities and the salsa school were amazing."
Australia
Jasmine
The price is ￥8,587
￥8,587 total
Oct 12 - Oct 13
Viajero Cali Hostel & Salsa School
Interior

6. Casa feliz

Casa feliz
1.0 star property
San Antonio
The price is ￥2,414
￥2,414 total
Oct 2 - Oct 3
Casa feliz
Full-size fridge, microwave, blender, cookware/dishes/utensils

7. Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is ￥3,469
￥3,469 total
Sep 20 - Sep 21
Epifania Guest House
Interior

8. casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
4.0 out of 10, (2 reviews)
"Cheap and convenient location. But mosquitoes in room every night and leaky toilet. There are better options available. "
Australia
Meyer
The price is ￥2,526
￥3,150 total
Sep 19 - Sep 20
casa hostal ave maria san antonio cali
Front of property

9. Hotel el Peñón By Bithotels

Hotel el Peñón By Bithotels
4.0 star property
El Peñon, 0.4 km from San Antonio
9.0 out of 10, Wonderful, (478 reviews)
"Great location and staff and hotel just right"
United States
Avadawn
The price is ￥9,965
￥9,965 total
Sep 27 - Sep 28
Hotel el Peñón By Bithotels
Interior entrance

10. Hotel Dann Cali

Hotel Dann Cali
3.0 star property
El Peñon, 0.4 km from San Antonio
8.6 out of 10, Excellent, (611 reviews)
"Nice hotel, nice buffet, excellent location and friendly staff, definitely I'll come back"
United States
Holmes
The price is ￥15,548
￥15,548 total
Sep 26 - Sep 27
Hotel Dann Cali
Standard Room, Multiple Beds | Living area | 42-inch TV with cable channels

11. Hotel Thama Palmira

Hotel Thama Palmira
3.0 star property
28 km from San Antonio
8.2 out of 10, Very good, (98 reviews)
"The staff was very nice and helpful The hotel location was Perfect i like the the hotel was very clean "
United States
Margarita
The price is ￥6,129
￥6,129 total
Sep 26 - Sep 27
Hotel Thama Palmira
Exterior detail

12. Passiflora luxury suite

Passiflora luxury suite
3.0 star property
1 km from San Antonio
10.0 out of 10, Exceptional, (1 review)
"No suggestions"
United States
Michelle
The price is ￥5,208
￥7,547 total
Sep 23 - Sep 24
Passiflora luxury suite
In-room safe, blackout drapes, iron/ironing board, WiFi (free)

13. Cali River Suites

Cali River Suites
3.0 star property
Centenario, 0.5 km from San Antonio
9.2 out of 10, Wonderful, (146 reviews)
"Near popular tourist attractions"
United States
Oliver
The price is ￥5,358
￥13,245 total
Sep 23 - Sep 24
Cali River Suites
Outdoor pool

14. Hotel Boutique Iyarí

Hotel Boutique Iyarí
3.0 star property
27.7 km from San Antonio
8.8 out of 10, Excellent, (6 reviews)
"Clean rooms and Phillipe was very helpful spoke perfect English."
United States
Morne
The price is ￥9,331
￥9,331 total
Oct 19 - Oct 20
Hotel Boutique Iyarí
Reception

15. Hotel Obelisco

Hotel Obelisco
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (548 reviews)
"The location is great with beautiful surroundings. Hotel personnel were very friendly and helpful, especially Doris in the front desk and the lady in charge of the breakfast buffet. Food was very good."
United States
Carlos
The price is ￥10,724
￥10,724 total
Oct 19 - Oct 20
Hotel Obelisco
Outdoor spa tub

16. Faranda Collection Cali, a member of Radisson Individuals

Faranda Collection Cali, a member of Radisson Individuals
4.0 star property
La Merced, 0.6 km from San Antonio
9.0 out of 10, Wonderful, (158 reviews)
"Amazing stay"
United States
Jose
The price is ￥16,172
￥16,172 total
Sep 19 - Sep 20
Faranda Collection Cali, a member of Radisson Individuals
Exterior

17. InterContinental Cali by IHG

InterContinental Cali by IHG
4.0 star property
El Peñon, 0.3 km from San Antonio
9.0 out of 10, Wonderful, (1,001 reviews)
"Very good hotel and staff"
United States
Pedro
The price is ￥22,457
￥22,457 total
Oct 3 - Oct 4
InterContinental Cali by IHG
Front of property

18. Hotel Stein Colonial

Hotel Stein Colonial
3.0 star property
Juanambú, 0.6 km from San Antonio
9.4 out of 10, Exceptional, (271 reviews)
"Super friendly staff, beautiful historic hotel, & great location/breakfast!"
United States
kevin
The price is ￥9,015
￥9,015 total
Sep 21 - Sep 22
Hotel Stein Colonial
Front of property

19. Altio hotel

Altio hotel
4.0 star property
El Peñon, 0.7 km from San Antonio
8.8 out of 10, Excellent, (193 reviews)
"it was ok. room had no view to outside. Good place to rest for the night but for me I wouldn't want a long stay there."
United States
Eric
The price is ￥7,279
￥7,279 total
Oct 19 - Oct 20
Altio hotel
Interior

20. Hotel Dann Carlton Cali

Hotel Dann Carlton Cali
3.5 star property
El Peñon, 0.4 km from San Antonio
8.8 out of 10, Excellent, (481 reviews)
"Loved our stay!"
United States
Doris
The price is ￥15,952
￥15,952 total
Sep 26 - Sep 27
Hotel Dann Carlton Cali
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.
A cityscape with dense urban buildings, a prominent hill, and a distant mountain range under a cloudy sky.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

A yellow monument with a bell, surrounded by trees and a fence.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

An aerial view of a city with dense high-rise buildings, a roundabout, and surrounding greenery.

El Peñon

When in El Peñon, you can plan a visit to Centenario Commercial Center and El Gato Del Rio, some noteworthy sights in the nearby area.

Pance

Pance might not have many top sights, but Chorrera del Indio and Los Arrayanes Recreational Center are two attractions nearby that you can check out.

Top San Antonio Hotel Reviews

NH Cali Royal

NH Cali Royal

10/10 Excellent
"."
Sonnya 4-night trip
Posted 1 day ago
NH Cali Royal

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Another good option for your stay in the area is Viajero Cali Hostel & Salsa School.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 52 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
Where can I learn more about changing or cancelling my trip to San Antonio?
For additional details about updating your trip to San Antonio or cancelling it, head over to our customer service page.
What can I see and do in this Cali neighborhood?
Centro Cultural de Cali, Religious Art Museum, and Enrique Buenaventura Municipal Theater are just a few of the places to visit in and around San Antonio. While you're out sightseeing, La Merced Archaeological Museum and Calima Gold Museum of the Bank of the Republic are a couple of additional sights to visit in Cali.

Explore a world of travel with Expedia