Saint Charles Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Saint Charles vacation rentals

Free WiFi, bed sheets
Quiet Studio on Grand Near Hospitals!

Apartment in Downtown Des Moines

Quiet Studio on Grand Near Hospitals!
8.6 out of 10, Excellent, (10)
"Pretty nice spot"
United States
Alberto P.
The price is ￥7,041
￥148,381 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Quiet Studio on Grand Near Hospitals!
Terrace/patio
Spacious Studio Unit in Des Moines

Apartment in Downtown Des Moines

Spacious Studio Unit in Des Moines
9.0 out of 10, Wonderful, (2)
"We really enjoyed our stay at this cute little Studio in Des Moines. The location is great - right next to the Capital and Interstate. Will be back again soon :)"
United States
Amber V.
The price is ￥7,806
￥21,025 total
includes taxes & fees
Dec 25 - Dec 26
Spacious Studio Unit in Des Moines
Interior
Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!

Apartment in Downtown Des Moines

Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!
10.0 out of 10, Exceptional, (2)
"No issues, everything went very smoothly. Second tv in bedroom is nice if you like watching TV in bed"
United States
Kevin B.
The price is ￥10,148
￥26,130 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Modern Comfort Meets Affordable Luxury – Your Perfect Stay Awaits!
1 bedroom, free WiFi, bed sheets
Sleepover: Impressive Studio and Gym - Des Moines

Apartment in Drake

Sleepover: Impressive Studio and Gym - Des Moines
10.0 out of 10, Exceptional, (2)
"The place was located right next door to Drake which made doing a campus visit easily walkable and so were restaurants. Found parking on the street nearby and didn’t have to move the car until checkout. "
United States
Thomas
The price is ￥8,290
￥27,646 total
includes taxes & fees
Dec 28 - Dec 29
Sleepover: Impressive Studio and Gym - Des Moines
Smart TV
Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking

Apartment in Downtown Des Moines

Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking
10.0 out of 10, Exceptional, (25)
"This was a great place, clean, comfortable and location is amazing."
United States
Krystal D.
The price is ￥11,061
￥28,125 total
includes taxes & fees
Dec 25 - Dec 26
Cozy 1B1B w/Wi-Fi, Balcony Views, Coffee + Parking
Game room
Kasa Downtown Des Moines

Aparthotel in Downtown Des Moines

Kasa Downtown Des Moines
4.0 star property
9.2 out of 10, Wonderful, (111)
"Excellent stay! Very clean apartment and safe building."
United States
Bill
The price is ￥14,612
￥26,857 total
includes taxes & fees
Dec 28 - Dec 29
Kasa Downtown Des Moines
Iron/ironing board, WiFi
Urban Jungle Retreat (417)

Apartment in Downtown Des Moines

Urban Jungle Retreat (417)
9.4 out of 10, Exceptional, (9)
"Very comfortable and convenient for a single traveler. "
United States
Jessica H.
The price is ￥7,806
￥21,876 total
includes taxes & fees
Dec 28 - Dec 29
Urban Jungle Retreat (417)
2 bedrooms, iron/ironing board, WiFi, bed sheets
Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping

Cottage in Woodland Heights

Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping
2.0 star property
10.0 out of 10, Exceptional, (2)
"Cozy, had everything we needed, convenient "
United States
Jordan S.
The price is ￥12,568
￥34,989 total
includes taxes & fees
Dec 29 - Dec 30
Cozy Cottage Near Downtown Walkable to Dining and Boutique Shopping
Smart TV
Boho Loft / Skyline View / Walk to Arena Events

Apartment in Downtown Des Moines

Boho Loft / Skyline View / Walk to Arena Events
10.0 out of 10, Exceptional, (6)
"Wonderful location! "
United States
Travis
The price is ￥10,476
￥27,471 total
includes taxes & fees
Dec 25 - Dec 26
Boho Loft / Skyline View / Walk to Arena Events
Smart TV
Modern Studio - walk to Wells Fargo Arena

Apartment in Downtown Des Moines

Modern Studio - walk to Wells Fargo Arena
9.0 out of 10, Wonderful, (8)
"The location was perfect for the Iowa Events Center. Good apartment, and very clean."
United States
Hugo M.
The price is ￥8,415
￥151,051 total
includes taxes & fees
Dec 25 - Dec 26
Modern Studio - walk to Wells Fargo Arena
Terrace/patio
Sleepover: Charming 1BD/1BA - Downtown Des Moines

Apartment in Woodland Heights

Sleepover: Charming 1BD/1BA - Downtown Des Moines
10.0 out of 10, Exceptional, (1)
"Convenient to Sherman Hill and downtown. Quiet. "
United States
Abby H.
The price is ￥11,100
￥30,793 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sleepover: Charming 1BD/1BA - Downtown Des Moines
Outdoor dining
A lush, green-themed retreat home in Des Moines’ vibrant East Village.

Apartment in Downtown Des Moines

A lush, green-themed retreat home in Des Moines’ vibrant East Village.
9.4 out of 10, Exceptional, (10)
"Very comfortable place to stay. Easy to get around to all events. The only thing i would change is the thickness of mattress was a bit hard on my old back. Would definitely book again "
United States
Anonymous traveler
The price is ￥7,806
￥21,876 total
includes taxes & fees
Dec 25 - Dec 26
A lush, green-themed retreat home in Des Moines’ vibrant East Village.
Fridge, microwave, oven, stovetop
Skyline Serenity 2BR/2BA with Stunning City Views

Apartment in Downtown Des Moines

Skyline Serenity 2BR/2BA with Stunning City Views
2.0 star property
9.8 out of 10, Exceptional, (8)
"Was a great place to stay with my girlfriends for a concert at the Casey's center - very walkable & close to many bars and food places. Liked the games in community room in the basement! Would definitely stay again. "
United States
Angela
The price is ￥10,304
￥27,430 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Skyline Serenity 2BR/2BA with Stunning City Views
TV
Chic Des Moines 1BR with Amenities & Prime Location

Apartment in Downtown Des Moines

Chic Des Moines 1BR with Amenities & Prime Location
2.0 star property
10.0 out of 10, Exceptional, (1)
"Awesome !!"
United States
Heather
The price is ￥7,806
￥21,876 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Chic Des Moines 1BR with Amenities & Prime Location
Smart TV
Cozy apartment with nice view-9

Apartment in Downtown Des Moines

Cozy apartment with nice view-9
9.0 out of 10, Wonderful, (19)
"I only stayed over night but it was very clean and cute. "
United States
Kailyn C.
The price is ￥13,668
￥26,429 total
includes taxes & fees
Dec 28 - Dec 29
Cozy apartment with nice view-9
Smart TV
Beautiful 2BR/2BA in Bldg connected to Skywalk

Apartment in Downtown Des Moines

Beautiful 2BR/2BA in Bldg connected to Skywalk
8.0 out of 10, Very Good, (13)
"Great service. Place was very nice and clean. Nice location for what we wanted to do. Would definitely stay again if we get back here. Owners were great to deal with. "
United States
Matt M.
The price is ￥10,304
￥157,163 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Beautiful 2BR/2BA in Bldg connected to Skywalk
Fridge, microwave, oven, stovetop
The Hen House Country Living with Farm Life Appeal Indianola, IA

Vacation Home in Indianola

The Hen House Country Living with Farm Life Appeal Indianola, IA
10.0 out of 10, Exceptional, (8)
"Lori and Les make you feel right at home. They go above and beyond to ensure you have everything you could need and more. The farm is so peaceful and watching the animals is entertaining."
United States
Valerie
The price is ￥21,076
￥29,670 total
includes taxes & fees
Dec 25 - Dec 26
The Hen House Country Living with Farm Life Appeal Indianola, IA
Interior
2 BR Dwntwn Apt with Hot Tub

Apartment in Downtown Des Moines

2 BR Dwntwn Apt with Hot Tub
9.0 out of 10, Wonderful, (9)
"It was a great location for Ironman 70.3. Just a little over a mile or so from both Greys lake and the finish line. I would stay there again!! Des Moines was a great experience. "
United States
Rob M.
The price is ￥12,193
￥159,453 total
includes taxes & fees
Dec 25 - Dec 26
2 BR Dwntwn Apt with Hot Tub
Dining
Sleepover: Wonderful 1BD/1BA -Downtown Des Moines

Apartment in Downtown Des Moines

Sleepover: Wonderful 1BD/1BA -Downtown Des Moines
9.6 out of 10, Exceptional, (8)
"The furniture is very comfortable. The check in and check out is very easy. Also a huge plus is that there a free lot to park in behind the building. Overall a great place to stay . We have stayed there a few times now. "
Canada
Gord J.
The price is ￥12,505
￥32,367 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sleepover: Wonderful 1BD/1BA -Downtown Des Moines
Living area
Beautiful & Spacious 2nd Floor Apartment

Apartment in Drake

Beautiful & Spacious 2nd Floor Apartment
10.0 out of 10, Exceptional, (7)
"10/10 would definitely stay again!"
United States
Requia C.
Beautiful & Spacious 2nd Floor Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Saint Charles Hotel Reviews

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

10/10 Excellent
"Very clean. Well maintained. Friendly staff. Nice breakfast selection. "
Doug 1-night trip
Posted 17 hours ago
Fairfield Inn and Suites by Marriott Des Moines West

Find out more about Saint Charles

Search for holiday rentals in Saint Charles on Expedia! You can easily find your home rentals, villas, holiday apartments in Saint Charles using one of the methods below:

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  • Enter your travel dates to view the best deals on holiday rentals in Saint Charles while they last

Look no further and take a look at our great range of rental properties in Saint Charles!

Frequently asked questions

Can I find vacation rentals in Saint Charles?

Yes, we have vacation rentals close to popular points of interest in Saint Charles, or you can choose a more secluded option if you'd like a relaxing place to stay.

What's the top vacation rental that Saint Charles has to offer?

LUXURY GETAWAY! ARCADE, POOL TBL, PING PONG, HOT TUB, DECK! ACCESS TO POOLS!: Visitors like this Saint Charles vacation home rental. It is located next to a golf course and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation.

What can I see and do in Saint Charles?

While exploring the area, visit family-friendly sights like Blank Park Zoo, or get outside and enjoy nature at Lake Ahquabi State Park. In the larger area, you’ll find Imes Bridge and John Wayne Birthplace Museum.

What are vacation rentals like in Saint Charles?

Vacation rentals are private properties you can stay in for a few days or a quick weekend in Saint Charles. Vacation rentals provide amenities such as patios, hot tubs, and fire pits to help you enjoy your stay. If you're concerned about a sanitized environment, vacation rentals can offer a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for a family getaway.