The Best Hotels Closest to Rochester Museum and Science Center in Rochester for 2026

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Our top choices for Rochester Museum and Science Center hotels

An outdoor café with tables and chairs, a sofa, and hanging pendant lights.

A modern indoor swimming pool with clear glass walls, lounge chairs, and a table with chairs.

A modern lounge area with a fireplace, seating, and a bar.

A modern hotel entrance with a blue sign reading "Welcome," a parking area with handicapped parking, and a flagpole with an American flag.

1. Hampton Inn & Suites Rochester Downtown

Rochester Central Business District, 1 km from Rochester Museum and Science Center

Steven

￥25,193

￥28,721 total

includes taxes & fees

Sep 20 - Sep 21

A staircase with a framed certificate on the wall, a small table with a sign, and a painting on the lower wall.

A modern kitchen with a dining area, built-in appliances, and a large window.

A bathroom with a wooden bed frame, a large mirror, a sink, and a shower.

A building entrance with a sign reading "531 at Colors Studios" and a set of lights above the door.

2. School 31 Lofts at Colors Studios

0.5 km from Rochester Museum and Science Center

Nena

￥26,682

￥30,418 total

includes taxes & fees

Sep 17 - Sep 18

An outdoor terrace with tables and chairs, overlooking a cityscape.

A grand staircase with ornate balustrades and a dome ceiling with a stained glass window.

A modern bar area with high stools and a long counter.

A sign for Strathallan, a doubletree by Hilton, with a stone base and illuminated letters.

3. The Strathallan Rochester Hotel & Spa, Tapestry by Hilton

East Avenue, 0.2 km from Rochester Museum and Science Center

Michelle

￥30,257

￥34,492 total

includes taxes & fees

Sep 20 - Sep 21

An indoor area with a wooden floor, glass doors leading to a space with chairs and potted plants.

A spacious lobby with multiple seating areas, a fireplace, and modern lighting fixtures.

A bar area with stools, shelves of bottles, and a television mounted on the wall.

A courtyard with wicker chairs, a central potted plant, and a stone wall.

4. Hilton Garden Inn Rochester Downtown, NY

Rochester Central Business District, 1.7 km from Rochester Museum and Science Center

Almira

￥21,522

￥25,075 total

includes taxes & fees

Sep 20 - Sep 21

A modern kitchen with a built-in microwave, stainless steel refrigerator, and a coffee maker. There is a small dining area with a table and chairs, and a window with blinds.

A hotel room with a bed, bedside lamp, nightstand, and a view of the kitchen area.

A modern hotel lobby with sofas, a coffee table, and a TV.

A modern hotel lobby with seating areas, a bar, and a television displaying sports.

5. Towneplace Suites By Marriott Rochester South

11.4 km from Rochester Museum and Science Center

Hope

￥16,929

￥19,299 total

includes taxes & fees

Sep 20 - Sep 21

A cozy room with two beds, a desk, and a chair. There is a window with blinds, a wall-mounted air conditioner, and a lamp on a wooden table.

A compact room with a white air conditioner, a wooden door, a brown leather chair, and a small decorative piece on the wall.

A playground with two slides and a swing set.

A laundry facility with a vending machine, washing machines, and a sign indicating soap, bleach, and softeners.

6. Sleepy Bear Inn

15.7 km from Rochester Museum and Science Center

Cory

￥16,897

￥20,760 total

includes taxes & fees

Oct 7 - Oct 8

A modern interior with a blue sofa, wooden tables, and patterned chairs.

A Hampton Inn & Suites hotel with a stone facade, multiple windows, and a parking lot.

A hotel reception desk with a 'Welcome to Hampton' sign, a digital screen, and a view of the cityscape.

A snack display with various packaged foods, a refrigerated section, and a blue sign indicating a frozen section.

7. Hampton Inn & Suites Rochester/Henrietta

7.9 km from Rochester Museum and Science Center

Douglas

￥20,028

￥22,832 total

includes taxes & fees

Oct 8 - Oct 9

A Holiday Inn Express building with outdoor seating and a well-lit facade.

A Holiday Inn Express hotel with a brick facade, multiple windows, and a covered entrance.

A hotel room with a bed, a sofa, a desk, and a chair.

A modern restaurant with high tables and blue chairs, a bar area, and a stone fireplace.

8. Holiday Inn Express & Suites Rochester Webster by IHG

13.5 km from Rochester Museum and Science Center

Sharon

￥17,512

￥19,963 total

includes taxes & fees

Oct 11 - Oct 12

A spacious hotel lobby with a long reception desk, multiple seating areas, and a modern chandelier.

An outdoor patio with a stone fire table, wicker furniture, and a stone wall.

A hotel reception area with a reception desk, a large framed picture, and a seating area with chairs.

A swimming pool with clear lane markings, adjacent lounge chairs, and a modern ceiling design.

9. Hampton Inn Rochester Penfield

8.7 km from Rochester Museum and Science Center

andre

￥19,278

￥21,977 total

includes taxes & fees

Oct 7 - Oct 8

An outdoor seating area with a fire pit, wicker furniture, and a view of the building's interior.

A modern kitchen with wooden cabinets, stainless steel appliances, and pendant lighting.

A modern indoor pool area with clear signage, seating around the pool, and large windows offering views of the outdoors.

A multi-story hotel with a covered parking area, a sign reading "Residence Inn by Marriott," and a landscaped entrance with trees.

10. Residence Inn by Marriott Rochester Henrietta

7.4 km from Rochester Museum and Science Center

Larissa

￥26,710

￥30,448 total

includes taxes & fees

Oct 7 - Oct 8

A modern dining area with a brick wall, wooden ceiling, and a variety of breakfast items on display.

A multi-story hotel with a prominent "Hilton Garden Inn" sign.

An outdoor patio with a round fire pit surrounded by wicker furniture.

A modern lobby with a seating area, a fireplace, and a television screen.

11. Hilton Garden Inn Rochester/University & Medical Center

Strong, 4.3 km from Rochester Museum and Science Center

Kyle

￥27,585

￥31,986 total

includes taxes & fees

Sep 21 - Sep 22

A Staybridge hotel with a modern facade, multiple windows, and a well-lit entrance.

A compact hotel room with a kitchenette, a bed, a desk, and a chair.

A hotel room with a large bed, two bedside tables with lamps, a wardrobe, and a window with curtains.

A hotel room with a bed, a sofa, a coffee table, a TV, and a painting on the wall.

12. Staybridge Suites Rochester University by IHG

19th Ward, 4.7 km from Rochester Museum and Science Center

Keith James

￥23,349

￥26,618 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor seating area with a fire pit, string lights, and brick pillars.

A hotel room with two beds, a desk with a TV, and a large window with curtains.

A spacious indoor area with multiple tables and chairs, a reception desk, and a counter with a beverage dispenser.

A hotel with a covered outdoor seating area, a well-lit entrance, and a landscaped front yard.

13. Country Inn & Suites by Radisson, Rochester-Pittsford/Brighton, NY

Brighton, 5.7 km from Rochester Museum and Science Center

Linda

￥19,539

￥22,273 total

includes taxes & fees

Oct 12 - Oct 13

A spacious dining area with high ceilings, exposed ductwork, and a patterned carpet.

A gym with exercise equipment, a mirror, and a TV on the wall.

A reception desk with a nameplate reading "MARRIOTT BONVOY," a digital screen, a coffee machine, and a window with curtains.

A neatly made bed with a headboard, a bedside lamp, and a nightstand with a lamp.

14. Fairfield Inn Marriott Rochester Airport

6.7 km from Rochester Museum and Science Center

Elvin

￥20,272

￥23,110 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor seating area with wicker furniture, cushions, and candles.

A modern living room with a flat-screen TV, a fireplace, a dining area, and a seating area.

A modern lobby with a reception desk, a staircase, and framed artwork on the walls.

A bar area with wooden bar counters, metal chairs, and a variety of bottles and glasses.

15. The Del Monte Lodge Renaissance Rochester Hotel & Spa

8.8 km from Rochester Museum and Science Center

Brian

￥44,086

￥50,259 total

includes taxes & fees

Sep 27 - Sep 28

A swimming pool with lounge chairs, a glass ceiling, and potted plants.

A restaurant with a central bar, multiple seating areas, and a view of the city through large windows.

A lobby with a stone fireplace, seating area, and a large TV screen.

A modern living room with a stone fireplace, comfortable seating, a flat-screen TV, and a bar area.

16. Courtyard by Marriott Rochester Brighton

Brighton, 5.8 km from Rochester Museum and Science Center

Stella

￥20,225

￥23,057 total

includes taxes & fees

Sep 20 - Sep 21

A hotel kitchen with a buffet setup, including a variety of food items and a coffee station.

A hotel with a clear sign reading "Hampton Inn."

An indoor swimming pool with lounge chairs and a sunbed area.

A hotel lobby with a seating area, a reception desk, and a dining area.

17. Hampton Inn Rochester Webster

12.4 km from Rochester Museum and Science Center

Maruf

￥14,635

￥16,685 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor patio with a barbecue area, seating, and a covered section.

A hotel with a modern design, featuring a central entrance and multiple floors.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.

A hotel room with a bed, bedside table, lamp, and a view of the cityscape.

18. Homewood Suites by Hilton Rochester/Greece, NY

9.2 km from Rochester Museum and Science Center

Carl

￥16,790

￥19,142 total

includes taxes & fees

Oct 11 - Oct 12

A spacious indoor seating area with multiple tables and benches, a counter, and a television screen.

A hotel room with a microwave, coffee maker, and a compact refrigerator. There are two beds with white linens, a desk with a chair, and a window with blinds.

A coffee station with two coffee machines and a display of coffee pods and cups.

An indoor swimming pool with a tiled floor, a pool ladder, and several lounge chairs along the wall.

19. Holiday Inn Express Hotel & Suites Rochester - Victor by IHG

19.7 km from Rochester Museum and Science Center

Rakan

￥18,740

￥20,707 total

includes taxes & fees

Sep 21 - Sep 22

An indoor swimming pool with wooden beams, clear glass windows, and lounge chairs.

A spacious hotel lobby with modern furniture, large windows, and a patterned carpet.

An outdoor seating area with a square fire pit surrounded by wicker chairs.

A modern hotel room with a grey sectional sofa, a small dining area with two chairs, a bar counter, a large mirror, and a floor lamp.

20. Residence Inn by Marriott Rochester West/Greece

9 km from Rochester Museum and Science Center

Peter

￥22,888

￥26,092 total

includes taxes & fees

Sep 13 - Sep 14

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Compare popular hotels close to Rochester Museum and Science Center

Property	Star rating	Guest rating
Hampton Inn & Suites Rochester Downtown	9.4 Exceptional 726 reviews	View
School 31 Lofts at Colors Studios	8.8 Excellent 616 reviews	View
The Strathallan Rochester Hotel & Spa, Tapestry by Hilton	9.0 Wonderful 1,000 reviews	View
Hilton Garden Inn Rochester Downtown, NY	8.2 Very Good 948 reviews	View
Towneplace Suites By Marriott Rochester South	9.4 Exceptional 60 reviews	View

Top Rochester Museum and Science Center Hotel Reviews

Hilton Garden Inn Rochester Downtown, NY

8/10 Good

"Construction right now and can’t park in their parking lot of pull up to the door. It was difficult to get there. Hotel was great other than that."

Hampton Inn & Suites Rochester Downtown

10/10 Excellent

"Great family-friendly hotel. Perfect for visiting the museum of play next to it. Also within walking distance of a few restaurants and a bakery. The staff was friendly and informative. The pool is clean and well maintained."

The Strathallan Rochester Hotel & Spa, Tapestry by Hilton

10/10 Excellent

"The desk young LADIES were GREAT. Breakfast staff GREAT also. Should bring back the valet parking. The parking lot was the one minus."

Oxford-Park Avenue Luxury Suite

10/10 Excellent

"Great location with very accommodating host."

Victorian Elegance: 2 Bedroom w/ King Beds off Park Ave

10/10 Excellent

"This is a great unit with two large bedrooms, living space and kitchen. The building is beautiful and a great location to great food. The host is fantastic. Highly recommend!"

Courtyard by Marriott Rochester Downtown

10/10 Excellent

"Rooms are large and clean. The staff in the bistro is always friendly and super helpful, always willing to make items to special order. We stay frequently to visit family and always have a great experience."

Remodeled Historical Unit With King Bed Walking Distance To Many Attractions!

10/10 Excellent

"This was a spectacular unit! Very Clean with a host who was extremely communicative. We loved the fact that Jines restaurant/diner was within walking distance as well as MANY other fabulous restaurants and shops. While The garage parking was nice to have,..it was one of two of our only minor complaint because of the narrow width of the garage opening. Our second minor complaint being the fact that the owner never mentions removing your shoes before entering the unit. With all that in mind.. We still highly recommend anyone and everyone who is going to Rochester to take advantage of renting this BEAUTIFUL unit.! It was a great stay in a perfect part of town."

Cozy 1-bedroom Apartment Steps from Park Ave with AC, WiFi

10/10 Excellent

"I was happy to stay here again in 2026 as my initial visit in 2025 was pleasant. The location is convenient to Eastman museum - my primary reason for coming to Rochester. I hope to stay here again in same room! I did not have a car but this lodging is near bus stops and walkable to grocery stores and restaurants. I recommend!"

Charming 2BR, near Park Ave with private balcony!

10/10 Excellent

"Lovely apartment in a large historic home just a block from the Eastman House. Great location, very comfortable!"

Other attractions near Rochester Museum and Science Center

A patterned pavement with illuminated text.

Memorial Art Gallery

10.0/10 (1 review)

From Ancient Egypt to Jackson Pollock and beyond, this sizable university museum brings works of art from the last 5,000 years to downtown Rochester.

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A large, stately building with a classical facade, surrounded by lush greenery and trees.

George Eastman Museum

9.4/10 (38 reviews)

Once owned by the founder of Kodak, this opulent mansion features a huge collection of early photography equipment, interesting architecture and beautiful gardens.

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Strasenburgh Planetarium

You can spend an afternoon studying the exhibits at Strasenburgh Planetarium during your travels in Rochester. Experience the entertainment choices or attend a sporting event in this family-friendly area.

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ARTWalk

8.6/10 (9 reviews)

You can take time to visit ARTWalk during your travels to Rochester. Experience the great live music or attend a sporting event in this family-friendly area.

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Dryden Theatre

You can get tickets for a performance at Dryden Theatre during your trip to Rochester. Experience the area's great live music or attend a sporting event.

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Village Gate

You can enjoy retail therapy at Village Gate during your visit to Rochester. Discover the top-notch restaurants and entertainment choices in this family-friendly area.

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Anthology

You can enjoy a show at Anthology during your trip to Rochester. Experience the area's live music or attend a sporting event.

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Three Heads Brewing

After visiting Three Heads Brewing, make a plan to see the other sights and activities in Rochester. Experience the area's art scene and museums.

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Frequently asked questions

What's the area like around Rochester Museum and Science Center?

Rochester Museum and Science Center is located in a family-friendly area of Rochester known for its great live music scene and top museums. If you're looking for a convenient place to stay, check out the 122 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Rochester Museum and Science Center?

Adjacent to Rochester Museum and Science Center, The Strathallan Rochester Hotel & Spa, Tapestry by Hilton is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a restaurant. Other good choices within a short distance include Hampton Inn & Suites Rochester Downtown and School 31 Lofts at Colors Studios.

How many hotels are there close to Rochester Museum and Science Center?

Expedia has 122 hotels and other accommodations within a mile from Rochester Museum and Science Center.

If I need to cancel the hotel reservation for my stay near Rochester Museum and Science Center, will I receive a refund?

Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to view the best deals near Rochester Museum and Science Center.

Where can I learn more about changing or cancelling my trip in the area near Rochester Museum and Science Center?

For more information about picking new dates or cancelling your stay near Rochester Museum and Science Center, click here.

What can I see and do near Rochester Museum and Science Center?

You might want to spend some time browsing the exhibits at Memorial Art Gallery, Susan B. Anthony House, or Stone Tolan House Museum. George Eastman Museum, Main Street Armory, and Pont de Rennes Bridge are monuments to see when you're exploring the area around Rochester Museum and Science Center. You can watch performances at Rochester Auditorium Theater, Eastman Theatre, and Geva Theatre Center if you're interested in local theater.

How can I get to Rochester Museum and Science Center?

To venture out into the surrounding area, hop on a train at Rochester Station. There may not be many public transportation choices near by Rochester Museum and Science Center so consider a car rental to maximize your time.

Find hotels near Rochester Museum and Science Center, Rochester from ￥16,685

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Treat yourself

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Our top choices for Rochester Museum and Science Center hotels

1. Hampton Inn & Suites Rochester Downtown

2. School 31 Lofts at Colors Studios

3. The Strathallan Rochester Hotel & Spa, Tapestry by Hilton

4. Hilton Garden Inn Rochester Downtown, NY

5. Towneplace Suites By Marriott Rochester South

6. Sleepy Bear Inn

7. Hampton Inn & Suites Rochester/Henrietta

8. Holiday Inn Express & Suites Rochester Webster by IHG

9. Hampton Inn Rochester Penfield

10. Residence Inn by Marriott Rochester Henrietta

11. Hilton Garden Inn Rochester/University & Medical Center

12. Staybridge Suites Rochester University by IHG

13. Country Inn & Suites by Radisson, Rochester-Pittsford/Brighton, NY

14. Fairfield Inn Marriott Rochester Airport

15. The Del Monte Lodge Renaissance Rochester Hotel & Spa

16. Courtyard by Marriott Rochester Brighton

17. Hampton Inn Rochester Webster

18. Homewood Suites by Hilton Rochester/Greece, NY

19. Holiday Inn Express Hotel & Suites Rochester - Victor by IHG

20. Residence Inn by Marriott Rochester West/Greece

Compare popular hotels close to Rochester Museum and Science Center

Top Rochester Museum and Science Center Hotel Reviews

Hilton Garden Inn Rochester Downtown, NY

Hampton Inn & Suites Rochester Downtown

The Strathallan Rochester Hotel & Spa, Tapestry by Hilton

Oxford-Park Avenue Luxury Suite

Victorian Elegance: 2 Bedroom w/ King Beds off Park Ave

Courtyard by Marriott Rochester Downtown

Remodeled Historical Unit With King Bed Walking Distance To Many Attractions!

Cozy 1-bedroom Apartment Steps from Park Ave with AC, WiFi

Charming 2BR, near Park Ave with private balcony!

Other attractions near Rochester Museum and Science Center

Memorial Art Gallery

George Eastman Museum

Strasenburgh Planetarium

ARTWalk

Dryden Theatre

Village Gate

Anthology

Three Heads Brewing

Frequently asked questions