A coastal town with a pier, boats, and a hillside with buildings.

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Check availability on Pythagorio Resorts & Hotels with Spas

Tonight
Aug 12 - Aug 13
Tomorrow
Aug 13 - Aug 14
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

Our top choices for Pythagorio hotels with a spa

Lobby lounge
Free daily buffet breakfast
Standard Triple Room with Window | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer
Reception

1. Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
  • Serene massages await at this eco-certified urban retreat with a steam room and rainfall showers for ultimate relaxation.
￥22,573
￥26,567 total
includes taxes & fees
Aug 31 - Sep 1
Doryssa Theorem Hotel
Body treatments, body wraps, body scrubs, facials, Ayurvedic treatments
Private beach nearby, sun loungers, beach umbrellas, beach towels
Private beach nearby, sun loungers, beach umbrellas, beach towels
2 outdoor pools, pool umbrellas, sun loungers

2. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
  • Rejuvenate at this beachfront hotel with a full-service spa and seaside yoga classes for total relaxation.
￥38,591
￥45,033 total
includes taxes & fees
Sep 1 - Sep 2
Doryssa Seaside Resort
Hot tub, body treatments, hydrotherapy, aromatherapy, body wraps
Private beach, sun loungers, beach umbrellas, beach towels
Private beach, sun loungers, beach umbrellas, beach towels
Suite, Private Pool ( Blu ) | Terrace/patio

3. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Seaside retreat offers rejuvenating spa treatments, private beach access, and indoor-outdoor pools.
￥35,604
￥41,761 total
includes taxes & fees
Aug 13 - Aug 14
Proteas Blu Resort - Adults Only
Executive Suite, Sea Facing | Balcony view
Executive Suite, Sea Facing | In-room safe, laptop workspace, blackout drapes, soundproofing
Studio | Balcony view
Exterior

4. Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
  • Revitalize with beachside spa services and seasonal pool at this coastal retreat with Turkish hammam and sauna.
￥25,693
￥29,985 total
includes taxes & fees
Sep 8 - Sep 9
Hydrele Beach Hotel
Seasonal outdoor pool
Deluxe Double Room, Beachfront | View from room
Beach bar
On the beach, free beach cabanas, sun loungers, beach umbrellas

5. Casa Cook Samos

Casa Cook Samos
Samos
  • Immerse in a beachfront boutique escape with 4 specialized treatment rooms and daily aromatherapy spa services for complete renewal.
￥59,077
￥67,474 total
includes taxes & fees
Aug 26 - Aug 27
Casa Cook Samos
Property grounds
Premium bedding, in-room safe, laptop workspace, blackout drapes
Property grounds
Superior Suite | Living area | 42-inch flat-screen TV with satellite channels, TV

6. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
  • Indulge in rejuvenating spa treatments at this boutique hotel with seasonal pool and garden oasis.
￥29,160
￥33,782 total
includes taxes & fees
Sep 7 - Sep 8
Doryssa Boutique Hotel
Signature Room with Sea View and Plunge Pool | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar
Deluxe Room with 1 King bed and Private Pool | Exterior
Restaurant
Couples treatment rooms, sauna, hot tub, steam room, massages

7. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
￥55,719
￥63,795 total
includes taxes & fees
Sep 1 - Sep 2
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Outdoor pool, an infinity pool, sun loungers
Double Room, Sea View | Minibar, in-room safe, iron/ironing board (on request), WiFi (free)
Suite, Sea View | Balcony view
Suite, Sea View | Terrace/patio

8. Armonia Bay Hotel

Armonia Bay Hotel
Samos
  • Mediterranean retreat offers rejuvenating seaside escapes with massages, infinity pools, and garden serenity.
￥36,755
￥41,182 total
includes taxes & fees
Aug 23 - Aug 24
Armonia Bay Hotel
Turkish bath, 2 treatment rooms, manicures and pedicures
Buffet
Outdoor pool, pool umbrellas, sun loungers
Reception

9. Aegeon

Aegeon
Samos
  • Unwind at this island hotel with tranquil spa treatments, including massage services in 2 treatment rooms and a relaxing Turkish bath.
￥12,084
￥14,157 total
includes taxes & fees
Sep 3 - Sep 4
Aegeon
Interior
Poolside bar
Exterior
2 outdoor pools, open 10:00 AM to 6:00 PM, pool umbrellas, sun loungers

10. Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa
Samos
  • Serene beachfront escape with two outdoor pools and an on-site spa offering rejuvenating treatments in scenic surroundings.
￥43,637
￥49,640 total
includes taxes & fees
Aug 21 - Aug 22
Samian Mare Hotel Suites & Spa
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Choose what matters most at spa hotels in Pythagorio

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with pools in Pythagorio

Private beach nearby, sun loungers, beach umbrellas, beach towels
Private beach nearby, sun loungers, beach umbrellas, beach towels
2 outdoor pools, pool umbrellas, sun loungers
Free daily buffet breakfast

Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
￥38,591
￥45,033 total
includes taxes & fees
Sep 1 - Sep 2
Doryssa Seaside Resort
Private beach, sun loungers, beach umbrellas, beach towels
Suite, Private Pool ( Blu ) | Terrace/patio
Bar (on property)
Private beach, sun loungers, beach umbrellas, beach towels

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
￥35,604
￥41,761 total
includes taxes & fees
Aug 13 - Aug 14
Proteas Blu Resort - Adults Only
Property grounds
2 bars/lounges, beach bar
Beach bar
On the beach, free beach cabanas, sun loungers, beach umbrellas

Casa Cook Samos

Casa Cook Samos
Samos
￥59,077
￥67,474 total
includes taxes & fees
Aug 26 - Aug 27
Casa Cook Samos
Executive Suite, Sea Facing | Balcony view
Buffet
Private beach, sun loungers, beach umbrellas, beach towels
Exterior

Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
￥25,693
￥29,985 total
includes taxes & fees
Sep 8 - Sep 9
Hydrele Beach Hotel
Property grounds
Reception
Premium bedding, in-room safe, laptop workspace, blackout drapes
Front of property

Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
￥29,160
￥33,782 total
includes taxes & fees
Sep 7 - Sep 8
Doryssa Boutique Hotel
View all properties

Spa hotels with free breakfast in Pythagorio

Free daily buffet breakfast
Massages
Reception
Reception

Doryssa Theorem Hotel

Doryssa Theorem Hotel
Samos
￥22,573
￥26,567 total
includes taxes & fees
Aug 31 - Sep 1
Doryssa Theorem Hotel
Private beach nearby, sun loungers, beach umbrellas, beach towels
Private beach nearby, sun loungers, beach umbrellas, beach towels
2 outdoor pools, pool umbrellas, sun loungers
Free daily buffet breakfast

Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
￥38,591
￥45,033 total
includes taxes & fees
Sep 1 - Sep 2
Doryssa Seaside Resort
Private beach, sun loungers, beach umbrellas, beach towels
Suite, Private Pool ( Blu ) | Terrace/patio
Bar (on property)
Private beach, sun loungers, beach umbrellas, beach towels

Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
￥35,604
￥41,761 total
includes taxes & fees
Aug 13 - Aug 14
Proteas Blu Resort - Adults Only
Executive Suite, Sea Facing | Balcony view
Buffet
Private beach, sun loungers, beach umbrellas, beach towels
Exterior

Hydrele Beach Hotel

Hydrele Beach Hotel
Samos
￥25,693
￥29,985 total
includes taxes & fees
Sep 8 - Sep 9
Hydrele Beach Hotel
Property grounds
2 bars/lounges, beach bar
Beach bar
On the beach, free beach cabanas, sun loungers, beach umbrellas

Casa Cook Samos

Casa Cook Samos
Samos
￥59,077
￥67,474 total
includes taxes & fees
Aug 26 - Aug 27
Casa Cook Samos
Property grounds
Reception
Premium bedding, in-room safe, laptop workspace, blackout drapes
Front of property

Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
￥29,160
￥33,782 total
includes taxes & fees
Sep 7 - Sep 8
Doryssa Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Pythagorio Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

10/10 Excellent
"Never regret staying at Doryssa. see you next time"
ilkay 4-night trip
Posted 5 days ago
Doryssa Seaside Resort
Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only

10/10 Excellent
"It’s was very hilly but they had buggy’s to come and take you up and down the only downside was there was no tea and coffee making facilities in the room the food was first class had no problems getting sun beds in the morning both round the pool and at the beach"
Carol 7-night trip
Posted 2 months ago
Proteas Blu Resort - Adults Only

Frequently asked questions

Looking for a spa hotel in Pythagorio?
Treat yourself to some pampering and book a hotel with a spa. Check out the historical sites and museums in Pythagorio—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness center, a hair salon, a beach bar, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Hydrele Beach Hotel and Proteas Blu Resort - Adults Only.
How many spa hotels are there in Pythagorio?
Among Expedia's 78 accommodation options in Pythagorio, there are 5 spa hotels.
What's there to see and do in Pythagorio?
Take in the sights and attractions that Pythagorio offers with a visit to Samos Pythagorion Archaeological Museum, Pythagoreion, and Castle of Lycurgus. If you have extra time while you're in the area, you might want to stop by Folklore Museum of the Nikolaos Dimitriou Foundation of Samos and Glicorisa Beach.
What is a Pythagorio spa hotel?
Spa hotels in Pythagorio feature on-site spas which offer services including therapies and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.