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Check prices for these dates

Tonight
May 7 - May 8
Tomorrow
May 8 - May 9
This weekend
May 8 - May 10
Next weekend
May 15 - May 17

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Our top choices for Puerto Santa Ana hotels

2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"great safe place will be back "
United States
Tracy
The price is ￥17,164
￥19,271 total
May 17 - May 18
Wyndham Guayaquil Puerto Santa Ana
Rooftop terrace

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (52 reviews)
"Very commensurate location and safe area"
United States
Luz
The price is ￥12,507
￥12,665 total
May 22 - May 23
River View suites Puerto Santa Ana gye
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (107 reviews)
"Lots of restaurants nearby"
Canada
kevin
The price is ￥14,399
￥14,555 total
May 8 - May 9
Luxury Suites Riverfront GYE
Exterior

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
3.3 km from Puerto Santa Ana
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ￥7,503
￥7,503 total
May 10 - May 11
Hotel La Ria Durán
Terrace/patio

Hotel del Parque

Hotel del Parque
4.5 star property
3.6 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (113 reviews)
"Breakfast excellent"
United States
Priscilla
The price is ￥67,061
￥73,767 total
May 14 - May 15
Hotel del Parque
Family House, Private Pool | Living area | Flat-screen TV

Casa con Piscina Privada para Familias

Casa con Piscina Privada para Familias
3.0 star property
15.7 km from Puerto Santa Ana
2.0 out of 10, (2 reviews)
"More cleaning, there was rotten garbage and a bad smell emanated"
United States
Isabel
The price is ￥20,197
￥23,323 total
May 10 - May 11
Casa con Piscina Privada para Familias
Free minibar, in-room safe, soundproofing, iron/ironing board

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ￥48,772
￥54,313 total
May 14 - May 15
Hotel Río Guayas by Art Hotels Ecuador
Lobby lounge

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (138 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ￥8,769
￥9,802 total
Jun 1 - Jun 2
Mansión del Río
Economy Double Room | In-room safe, free WiFi

Malecon Guesthouse

Malecon Guesthouse
3.0 star property
River City, 1 km from Puerto Santa Ana
The price is ￥2,188
￥3,908 total
May 8 - May 9
Malecon Guesthouse
Honeymoon Double Room | Minibar, desk, laptop workspace, free WiFi

HOTEL PERLA CENTRAL MALECON

HOTEL PERLA CENTRAL MALECON
2.5 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
7.2 out of 10, Good, (21 reviews)
"Balcony view was very cool "
United States
Julio
The price is ￥4,437
￥4,437 total
May 18 - May 19
HOTEL PERLA CENTRAL MALECON
Indoor pool, open 8:00 AM to 10 PM, sun loungers

Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very Good, (404 reviews)
"Enjoyed a weekend in Guayaquil. Staff is attentive and genuinely helpful. The hotel is an older property but well-maintained — good price point for the area and what it offers. Breakfast was good. Solid choice for a quiet, relaxed stay in a central location"
United States
Hugo
The price is ￥9,848
￥10,004 total
Jun 3 - Jun 4
Hotel Ramada
Ecotours

Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
8.4 out of 10, Very Good, (8 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is ￥6,066
￥6,222 total
Jun 7 - Jun 8
Fortune Hotel
Lobby

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (90 reviews)
"Excellent in every aspect. Friendly staff. Comfortable rooms. "
United States
Juan
The price is ￥10,497
￥12,329 total
May 30 - May 31
Doubletree By Hilton Guayaquil
Restaurant

Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (305 reviews)
"Ibis hotel was amazing. Clean rooms, comfortable beds, great shower. Amazing view. The breakfast and dinner were delicious. Great variety and fresh food. We totally recommend it. "
Canada
Mayssam
The price is ￥9,379
￥10,551 total
May 10 - May 11
Ibis Styles El Malecon Guayaquil
Exterior

La Fontana Hotel

La Fontana Hotel
2.5 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
8.0 out of 10, Very Good, (110 reviews)
"Room was excellent, service was excellent, Safe, easy check in-check out"
United States
Abraham
The price is ￥8,441
￥8,441 total
Jun 6 - Jun 7
La Fontana Hotel
Front of property

Hotel Malecon Inn

Hotel Malecon Inn
3.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
6.8 out of 10, (123 reviews)
"They need a free breakfast, like most hotels"
United States
Naomi
The price is ￥3,842
￥4,000 total
Jun 3 - Jun 4
Hotel Malecon Inn
Lobby

Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (932 reviews)
"Excellent service"
United States
Maritza
The price is ￥9,264
￥10,424 total
Jun 6 - Jun 7
Hotel Palace Guayaquil
Food and drink

Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very Good, (153 reviews)
"Excellent!!"
United States
Alfredo
The price is ￥7,194
￥7,350 total
May 30 - May 31
Hotel Patrimonial by Greenfield
Standard Double Room, 1 Queen Bed | Individually decorated, individually furnished, desk, laptop workspace

The Park Hotel

The Park Hotel
2.5 star property
Rocafuerte, 2 km from Puerto Santa Ana
8.4 out of 10, Very Good, (36 reviews)
"I really enjoyed the location of the property and friendliness of the staff!"
Canada
Isaiah
The price is ￥7,389
￥8,128 total
Jun 6 - Jun 7
The Park Hotel
Free daily buffet breakfast

Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Nice hotel - great location for business travel "
United States
DISLEY
The price is ￥10,786
￥12,256 total
May 9 - May 10
Unipark by Oro Verde Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Central Market are some notable places to visit nearby.

Top Puerto Santa Ana Hotel Reviews

Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

2/10 Terrible
"Me dieron una habitación que su aire acondicionado no funcionaba bien.... cuando llamé a recepción no me contestaba nadie y con el calor fue una noche terrible. No puede ser que no haya nadie en recepción en la noche para atender estos temas."
DIEGO 1-night trip
Posted 4 hours ago
Ibis Styles El Malecon Guayaquil

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 85 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.