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Check prices for these dates

Tonight
Mar 3 - Mar 4
Tomorrow
Mar 4 - Mar 5
This weekend
Mar 6 - Mar 8
Next weekend
Mar 13 - Mar 15

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Our top choices for Puerto Santa Ana hotels

Rooftop terrace

River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
8.8 out of 10, Excellent, (47 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is ￥10,874
￥11,030 total
Apr 3 - Apr 4
River View suites Puerto Santa Ana gye
Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (104 reviews)
"The property was very clean and well maintained. Lots of security. The building is on the riverfront with many excellent restaurants within a few steps. Vibrant night life which was unfortunately very noisy when trying to sleep. Within walking distance to many attractions."
United States
Carolyn
The price is ￥17,384
￥17,541 total
Mar 13 - Mar 14
Luxury Suites Riverfront GYE
2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Clean rooms,great staff and very good food"
Canada
Abel Patricio
The price is ￥14,154
￥15,962 total
Mar 28 - Mar 29
Wyndham Guayaquil Puerto Santa Ana
Comfort Apartment, Kitchenette

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
The price is ￥6,242
￥6,242 total
Mar 4 - Mar 5
Guayacan Apart Hotel
Standard Double Room | Desk, free WiFi

Hostal Bicentenario

Hostal Bicentenario
2.0 star property
Downtown Guayaquil, 1.5 km from Puerto Santa Ana
6.0 out of 10, (4 reviews)
"The gentleman that checked me and my family in was amazing. He helped me get my car parked in the designated parking area, got my wife hot water to wash our baby's bottles, printed up copies of receipts I needed for a U.S. Consulate interview and was a very nice and helpful to myself and my family."
United States
Matthew
Hostal Bicentenario
Junior Suite, 1 Double Bed, Kitchenette | Premium bedding, free WiFi, bed sheets

San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 1.4 km from Puerto Santa Ana
6.2 out of 10, (23 reviews)
"Receptionist was very helpful finding us delivery food on arrival."
United States
William
The price is ￥5,462
￥5,618 total
Mar 5 - Mar 6
San Francisco Apart Hotel
Reception

Hostal California Inn

Hostal California Inn
3.0 star property
1.5 km from Puerto Santa Ana
8.4 out of 10, Very Good, (10 reviews)
"Spacious room with excellent storage. Very clean "
Canada
Brenda
Hostal California Inn
Property entrance

Hotel Presidente Internacional

Hotel Presidente Internacional
3.5 star property
1.6 km from Puerto Santa Ana
6.2 out of 10, (28 reviews)
"Nos gustó mucho limpio "
United States
Luis Miguel
Hotel Presidente Internacional
Exterior

La Fontana Hotel

La Fontana Hotel
2.5 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
8.0 out of 10, Very Good, (110 reviews)
"Room was excellent, service was excellent, Safe, easy check in-check out"
United States
Abraham
La Fontana Hotel
Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel
3.5 star property
Urdesa, 3.3 km from Puerto Santa Ana
8.6 out of 10, Excellent, (88 reviews)
"Its a small and beatiful hotel, good location, nice and modern with excelent service. its a very good choice"
United States
LIBARDO
The price is ￥10,524
￥11,732 total
Mar 4 - Mar 5
Cedros Inn Boutique Hotel
Terrace/patio

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
4.9 km from Puerto Santa Ana
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
The price is ￥2,471
￥2,471 total
Mar 4 - Mar 5
Villa Celeste - VC
Outdoor pool

Tropical Inn

Tropical Inn
2.0 star property
4.5 km from Puerto Santa Ana
8.0 out of 10, Very Good, (18 reviews)
"for the price was good"
United States
Rosa
Tropical Inn
Restaurant

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ￥43,070
￥48,040 total
Mar 4 - Mar 5
Hotel Río Guayas by Art Hotels Ecuador
Honeymoon Double Room | Minibar, desk, laptop workspace, free WiFi

HOTEL PERLA CENTRAL MALECON

HOTEL PERLA CENTRAL MALECON
2.5 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
7.4 out of 10, Good, (19 reviews)
"Balcony view was very cool "
United States
Julio
The price is ￥5,285
￥5,285 total
Mar 18 - Mar 19
HOTEL PERLA CENTRAL MALECON
Family House, Private Pool | Living area | Flat-screen TV

Casa con Piscina Privada para Familias

Casa con Piscina Privada para Familias
3.0 star property
15.7 km from Puerto Santa Ana
2.0 out of 10, (2 reviews)
"More cleaning, there was rotten garbage and a bad smell emanated"
United States
Isabel
The price is ￥20,162
￥23,283 total
Mar 4 - Mar 5
Casa con Piscina Privada para Familias
Down comforters, desk, free WiFi, bed sheets

Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
8.4 out of 10, Very Good, (108 reviews)
"The air conditioning was great and the location was very good."
United States
Rommel
Hotel Las Peñas
Superior Double Room, 2 Twin Beds | Free WiFi, bed sheets

Hotel GH Sander

Hotel GH Sander
3.0 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.8 out of 10, Excellent, (16 reviews)
"great property. i would definitely come back again every time i come to guayaquil"
United States
George
Hotel GH Sander
Front of property

Hotel Sada

Hotel Sada
3.0 star property
1.5 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (11 reviews)
"Todo excelente.. habitación cómodas, limpias y el personal excepcional.. de hecho aquí sigo "
Mexico
Lucas
The price is ￥7,236
￥7,392 total
Mar 5 - Mar 6
Hotel Sada
Ecotours

Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
8.0 out of 10, Very Good, (7 reviews)
"Very bad Hotel. Not using Expedia again. "
United States
Bryan
The price is ￥6,773
￥6,930 total
Apr 3 - Apr 4
Fortune Hotel
Comfort Double Room | In-room safe, desk, free WiFi, bed sheets

Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.4 out of 10, Very Good, (37 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
Hotel GH Alexander
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

They are here because people started feeding them
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Central Market are some notable places to visit nearby.

Cityscape from Malecón 2000, the boardwalk overlooking the Guayas River in Guayaquil, Ecuador's largest city and economic capital.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Iguanas at Seminario Park (Iguanas Park) - Guayaquil, Ecuador

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Top Puerto Santa Ana Hotel Reviews

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

10/10 Excellent
"Pool is great, front desk was very helpful with organizing a ride to the airport and helping with the luggage. "
Anthony 1-night trip
Posted 4 hours ago
TRYP by Wyndham Guayaquil Airport

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 83 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.