Photo by Paula Vernimmen

Find hotels in Puerto Santa Ana, Guayaquil from ￥6,691

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
Next weekend
Sep 5 - Sep 7
In two weeks
Sep 12 - Sep 14

Filter by

Guest rating
Guest rating
Star rating

Discover 389 Puerto Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel del Parque
Terrace/patio

Hotel del Parque

4.5 star property
9.8 out of 10, Exceptional, (97)
"N/A"
The price is ￥63,084
￥69,392 total
Sep 4 - Sep 5
Hotel del Parque
DC Suites Aeropuerto
Lobby

DC Suites Aeropuerto

3.0 star property
9.0 out of 10, Wonderful, (551)
"Staff was very friendly and had a quick check-in. Loved the cat in the lobby."
DC Suites Aeropuerto
Holiday Inn Guayaquil Airport by IHG
Outdoor pool

Holiday Inn Guayaquil Airport by IHG

3.5 star property
9.2 out of 10, Wonderful, (1007)
"Very nice hotel and close to the airport."
The price is ￥14,852
￥16,705 total
Sep 6 - Sep 7
Holiday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana
Presidential Suite, 1 King Bed, Jetted Tub, River View | 1 bedroom, Egyptian cotton sheets, premium bedding, down comforters

Wyndham Guayaquil Puerto Santa Ana

4.5 star property
9.2 out of 10, Wonderful, (1009)
"Nice hotel and good location "
The price is ￥16,146
￥18,129 total
Sep 14 - Sep 15
Wyndham Guayaquil Puerto Santa Ana
Luxury Suites Riverfront GYE
43-inch flat-screen TV with digital channels, TV, Netflix

Luxury Suites Riverfront GYE

3.5 star property
9.4 out of 10, Exceptional, (94)
"Beautiful view"
The price is ￥16,255
￥16,402 total
Sep 11 - Sep 12
Luxury Suites Riverfront GYE
River View suites Puerto Santa Ana gye
Outdoor pool

River View suites Puerto Santa Ana gye

3.0 star property
8.4 out of 10, Very Good, (34)
"Todo exelente "
The price is ￥11,778
￥11,925 total
Sep 1 - Sep 2
River View suites Puerto Santa Ana gye
TRYP by Wyndham Guayaquil Airport
Exterior

TRYP by Wyndham Guayaquil Airport

4.5 star property
8.8 out of 10, Excellent, (1004)
"Everything was great"
The price is ￥14,705
￥16,543 total
Sep 5 - Sep 6
TRYP by Wyndham Guayaquil Airport
Unipark by Oro Verde Hotels
Reception

Unipark by Oro Verde Hotels

4.0 star property
9.0 out of 10, Wonderful, (1011)
"Updated building recently bought by oro verde hotels group Great breakfast!"
The price is ￥10,294
￥11,691 total
Sep 6 - Sep 7
Unipark by Oro Verde Hotels
Grand Hotel Guayaquil, an Ascend Collection Hotel
Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers

Grand Hotel Guayaquil, an Ascend Collection Hotel

4.0 star property
9.2 out of 10, Wonderful, (939)
"The hotel and staff were great. "
The price is ￥9,999
￥11,220 total
Sep 14 - Sep 15
Grand Hotel Guayaquil, an Ascend Collection Hotel
Oro Verde Guayaquil
Children's activities

Oro Verde Guayaquil

5.0 star property
9.4 out of 10, Exceptional, (1007)
"Is a great place to stay "
The price is ￥14,558
￥16,382 total
Sep 28 - Sep 29
Oro Verde Guayaquil
Wyndham Garden Guayaquil
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1005)
"Very nice place, clean, kind staff, good location "
The price is ￥11,778
￥13,177 total
Sep 14 - Sep 15
Wyndham Garden Guayaquil
Sheraton Guayaquil Hotel
2 restaurants, breakfast, lunch, dinner served; Regional cuisine

Sheraton Guayaquil Hotel

5.0 star property
9.0 out of 10, Wonderful, (579)
"Excellent service from the staff and just seven minutes away from the airport. "
The price is ￥19,484
￥21,801 total
Sep 14 - Sep 15
Sheraton Guayaquil Hotel
Ibis Styles El Malecon Guayaquil
Exterior

Ibis Styles El Malecon Guayaquil

4.0 star property
9.4 out of 10, Exceptional, (237)
"This hotel is a good value for your money..."
The price is ￥8,823
￥9,926 total
Sep 6 - Sep 7
Ibis Styles El Malecon Guayaquil
Hotel Palace Guayaquil
Lobby

Hotel Palace Guayaquil

4.0 star property
9.2 out of 10, Wonderful, (897)
"Good place to stay "
The price is ￥9,279
￥10,428 total
Sep 5 - Sep 6
Hotel Palace Guayaquil
Courtyard by Marriott Guayaquil
Lobby

Courtyard by Marriott Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1004)
"Great stay "
The price is ￥11,779
￥13,178 total
Sep 26 - Sep 27
Courtyard by Marriott Guayaquil
Hilton Colon Guayaquil
Lobby

Hilton Colon Guayaquil

4.5 star property
8.6 out of 10, Excellent, (761)
"Really nice hotel and staff."
The price is ￥14,874
￥16,729 total
Sep 27 - Sep 28
Hilton Colon Guayaquil
Hotel Puerto Pacifico Guayaquil Airport
Massages

Hotel Puerto Pacifico Guayaquil Airport

4.0 star property
8.8 out of 10, Excellent, (205)
"Nice staff - clean & modern facilities & good breakfast buffet (& included w my booking)."
Hotel Puerto Pacifico Guayaquil Airport
Doubletree By Hilton Guayaquil
In-room safe, blackout drapes, soundproofing, iron/ironing board

Doubletree By Hilton Guayaquil

3.5 star property
9.2 out of 10, Wonderful, (45)
"The staff is amazing and the hotel is so beautiful."
The price is ￥10,374
￥11,558 total
Sep 6 - Sep 7
Doubletree By Hilton Guayaquil
Hotel La Ria Durán
Premium bedding, desk, laptop workspace, iron/ironing board

Hotel La Ria Durán

3.0 star property
7.2 out of 10, Good, (19)
The price is ￥6,691
￥6,691 total
Sep 1 - Sep 2
Hotel La Ria Durán
Mansión del Río
Lobby lounge

Mansión del Río

3.5 star property
8.6 out of 10, Excellent, (126)
"R"
The price is ￥8,734
￥9,754 total
Sep 2 - Sep 3
Mansión del Río
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Garzota

The restaurants and shopping are a few reasons travelers visit Garzota. Though there aren't many top sights in the neighborhood, you can visit Mall del Sol Shopping Center and Plaza del Sol, a few notable attractions nearby.

Top Puerto Santa Ana Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Puerto Santa Ana?

Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.

Where is the best hotel for a stay in Puerto Santa Ana?

Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Other good choices for your stay in the area include Luxury Suites Riverfront GYE and Administradora Condominio Guayaquil.

How many hotels will I find in Puerto Santa Ana?

If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 69 Puerto Santa Ana hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.

Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?

To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.

What is there to do around this Guayaquil neighborhood?

Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.