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Check prices for these dates

Tonight
Jan 16 - Jan 17
Tomorrow
Jan 17 - Jan 18
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

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Our top choices for Puerto Santa Ana hotels

Outdoor spa tub

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (101 reviews)
"The apartment was in a great location and very clean and well maintained."
United States
Rolando
The price is ￥16,556
￥16,715 total
Jan 26 - Jan 27
Luxury Suites Riverfront GYE
2 bars/lounges, lobby lounge

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Clean rooms,great staff and very good food"
Canada
Abel Patricio
The price is ￥15,819
￥17,798 total
Jan 20 - Jan 21
Wyndham Guayaquil Puerto Santa Ana
Standard Double Room | Desk, free WiFi

Hostal Bicentenario

Hostal Bicentenario
2.0 star property
Downtown Guayaquil, 1.5 km from Puerto Santa Ana
4.8 out of 10, (3 reviews)
"The gentleman that checked me and my family in was amazing. He helped me get my car parked in the designated parking area, got my wife hot water to wash our baby's bottles, printed up copies of receipts I needed for a U.S. Consulate interview and was a very nice and helpful to myself and my family."
United States
Matthew
Hostal Bicentenario
Junior Suite, 1 Double Bed, Kitchenette | Premium bedding, free WiFi, bed sheets

San Francisco Apart Hotel

San Francisco Apart Hotel
3.0 star property
La Atarazana, 1.4 km from Puerto Santa Ana
6.2 out of 10, (23 reviews)
"Receptionist was very helpful finding us delivery food on arrival."
United States
William
The price is ￥5,406
￥5,564 total
Jan 31 - Feb 1
San Francisco Apart Hotel
Comfort Apartment, Kitchenette

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
The price is ￥6,338
￥6,338 total
Jan 19 - Jan 20
Guayacan Apart Hotel
Reception

Hostal California Inn

Hostal California Inn
3.0 star property
1.5 km from Puerto Santa Ana
8.6 out of 10, Excellent, (8 reviews)
"Me encantó, es muy cómoda, la habitación super amplia y limpia Si duda volveré "
Mexico
Anita
Hostal California Inn
Property entrance

Hotel Presidente Internacional

Hotel Presidente Internacional
3.5 star property
1.6 km from Puerto Santa Ana
6.0 out of 10, (27 reviews)
"La ubicación es excelente. Cerca de todo "
Colombia
Myriam
Hotel Presidente Internacional
Exterior

La Fontana Hotel

La Fontana Hotel
2.5 star property
Downtown Guayaquil, 1.6 km from Puerto Santa Ana
8.0 out of 10, Very Good, (110 reviews)
"Room was excellent, service was excellent, Safe, easy check in-check out"
United States
Abraham
La Fontana Hotel
Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel
3.5 star property
Urdesa, 3.3 km from Puerto Santa Ana
8.4 out of 10, Very Good, (86 reviews)
"The staff went above and beyond to accommodate any special needs that we had. The place itself is clean and very beautiful. Great location, near many restaurants (and Chabad). 10/10 recommend booking your stay here. "
United States
Chana
The price is ￥10,057
￥11,222 total
Jan 17 - Jan 18
Cedros Inn Boutique Hotel
Terrace/patio

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
4.9 km from Puerto Santa Ana
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
Villa Celeste - VC
Family House, Private Pool | Living area | Flat-screen TV

Casa con Piscina Privada para Familias

Casa con Piscina Privada para Familias
3.0 star property
15.7 km from Puerto Santa Ana
2.0 out of 10, (1 review)
"More cleaning, there was rotten garbage and a bad smell emanated"
United States
Isabel
The price is ￥16,993
￥20,162 total
Feb 1 - Feb 2
Casa con Piscina Privada para Familias
Outdoor pool

Tropical Inn

Tropical Inn
2.0 star property
4.5 km from Puerto Santa Ana
8.2 out of 10, Very Good, (14 reviews)
"for the price was good"
United States
Rosa
Tropical Inn
Restaurant

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 0.6 km from Puerto Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ￥44,008
￥49,083 total
Jan 18 - Jan 19
Hotel Río Guayas by Art Hotels Ecuador
Down comforters, desk, free WiFi, bed sheets

Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 1.8 km from Puerto Santa Ana
8.4 out of 10, Very Good, (103 reviews)
"The location is excellent and the staff are very helpful "
United States
Albert
Hotel Las Peñas
Honeymoon Double Room | Minibar, desk, laptop workspace, free WiFi

HOTEL PERLA CENTRAL MALECON

HOTEL PERLA CENTRAL MALECON
2.5 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
7.6 out of 10, Good, (18 reviews)
"Balcony view was very cool "
United States
Julio
The price is ￥4,606
￥4,606 total
Feb 8 - Feb 9
HOTEL PERLA CENTRAL MALECON
Deluxe Studio Suite, Jetted Tub | Minibar, free WiFi, bed sheets

Hotel Sada

Hotel Sada
3.0 star property
1.5 km from Puerto Santa Ana
9.8 out of 10, Exceptional, (8 reviews)
"前に泊まったデラックスルームより今回泊まったシングルルームの方が高かったのが不思議ですが、部屋は快適で綺麗でした。朝食が毎回違うのが楽しみでした。"
Japan
MAKI
The price is ￥6,203
￥6,361 total
Feb 8 - Feb 9
Hotel Sada
Superior Double Room, 2 Twin Beds | Free WiFi, bed sheets

Hotel GH Sander

Hotel GH Sander
3.0 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.6 out of 10, Excellent, (14 reviews)
"great property. i would definitely come back again every time i come to guayaquil"
United States
George
Hotel GH Sander
Ecotours

Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
8.0 out of 10, Very Good, (7 reviews)
"Very bad Hotel. Not using Expedia again. "
United States
Bryan
The price is ￥7,130
￥7,288 total
Jan 19 - Jan 20
Fortune Hotel
Suite, Jetted Tub | In-room safe, free WiFi, bed sheets

Hotel Varadero Internacional

Hotel Varadero Internacional
3.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
8.0 out of 10, Very Good, (65 reviews)
"Overall a good place to stay and close to most destinations."
United States
Daniel
Hotel Varadero Internacional
Comfort Double Room | In-room safe, desk, free WiFi, bed sheets

Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 2.1 km from Puerto Santa Ana
8.6 out of 10, Excellent, (36 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
Hotel GH Alexander
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like San Francisco Square and Central Market while you're in town.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and George Capwell Stadium are some notable places to visit nearby.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Simón Bolívar

If you're spending some time in Simón Bolívar, Mall del Sol Shopping Center and Plaza del Sol are top sights worth seeing.

Top Puerto Santa Ana Hotel Reviews

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

10/10 Excellent
"Very good "
Anna 1-night trip
Posted 2 days ago
TRYP by Wyndham Guayaquil Airport

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighborhood that travelers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveler data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels will I find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 82 Puerto Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review top deals in Puerto Santa Ana.
Where can I learn more about changing or cancelling my trip to Puerto Santa Ana?
To access more information about updating your trip to Puerto Santa Ana or cancelling it, head over to our customer service page.
What is there to do around this Guayaquil neighborhood?
Emporium by The Point, Santa Ana Garden, and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.