A beach with waves and a sky with clouds.

Search Vacation Homes in Port Saint Lucie

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Port Saint Lucie vacation homes

A spacious living area with a dining table, sofa, and a kitchen in the background.

1. Cozy Oasis

Cozy Oasis
Port St. Lucie
9.0 out of 10, Wonderful, (90 reviews)
"The house was great"
United States
Carlos
The price is ￥14,016
￥42,127 total
includes taxes & fees
Sep 25 - Sep 26
Cozy Oasis
A hot tub with a built-in massage function, surrounded by string lights.

2. Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!

Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
Port St. Lucie
9.8 out of 10, Exceptional, (8 reviews)
"Friendly host, great room and amazing pool and hot tub. "
United States
Matthew B.
The price is ￥17,933
￥26,535 total
includes taxes & fees
Sep 24 - Sep 25
Poolside Private King Room PSL Shared Home w Hot Tub, read entire description!
A neatly made bed with a striped blanket, a bedside lamp, and multiple pillows.

3. La Dolce Vita Studio

La Dolce Vita Studio
Port St. Lucie
9.6 out of 10, Exceptional, (11 reviews)
"Great location.Room is excellent with all basic needs.Will book again."
United States
james h.
The price is ￥15,745
￥42,984 total
includes taxes & fees
Sep 24 - Sep 25
La Dolce Vita Studio
An aerial view of a coastal area with a long pier extending into the sea, a beach with a few people, and buildings along the shore.

4. Lush | Tropical | Modern Home w/ Heated Pool & Spa

Lush | Tropical | Modern Home w/ Heated Pool & Spa
Sandhill Crossing
10.0 out of 10, Exceptional, (28 reviews)
"Loved the house and the pool area!"
United States
Brandy
The price is ￥18,883
￥72,923 total
includes taxes & fees
Sep 24 - Sep 25
Lush | Tropical | Modern Home w/ Heated Pool & Spa
A covered outdoor area with a pool, seating, and a kitchen area.

5. Port St. Lucie Poolside Oasis

Port St. Lucie Poolside Oasis
2.0 star property
Port Saint Lucie
The price is ￥25,371
￥76,337 total
includes taxes & fees
Oct 6 - Oct 7
Port St. Lucie Poolside Oasis
A beach with clear water, a sandy shore, and a clear sky.

6. Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!

Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!
Port St. Lucie
10.0 out of 10, Exceptional, (5 reviews)
"Muy acogedor , excelente para pasar en familia , con todas las condiciones 👌"
United States
Jeiny
The price is ￥24,918
￥71,167 total
includes taxes & fees
Sep 25 - Sep 26
Modern 3BR Pool Home w/Lanai - Beaches, Golf, Boating: PSL Coastal Calm Retreat!
A modern kitchen with white cabinets, a stainless steel refrigerator, a built-in oven, and a granite countertop.

7. BR Tropical Oasis in Port St Lucie

BR Tropical Oasis in Port St Lucie
Port Saint Lucie
8.6 out of 10, Excellent, (4 reviews)
"We are a construction company that had workers in from out of town and the place was great "
United States
Sabrina B.
BR Tropical Oasis in Port St Lucie
A covered pool area with a glass roof, red and white patterned chairs, and a ceiling fan.

8. golf view villa near beach

golf view villa near beach
Sandpiper Bay
9.0 out of 10, Wonderful, (2 reviews)
"Host was very responsive and followed up on any issues that arose. "
United States
Joseph M.
The price is ￥30,860
￥80,381 total
includes taxes & fees
Sep 24 - Sep 25
golf view villa near beach
A bookshelf with various books, a framed picture of the ocean, a desk lamp, and a woven basket.

9. Bohemian Bungalow

Bohemian Bungalow
Port St. Lucie
10.0 out of 10, Exceptional, (8 reviews)
"This was the perfect place to stay. The house had everything we could need and Lisa was wonderful!"
United States
Sydney M.
The price is ￥21,185
￥56,005 total
includes taxes & fees
Sep 30 - Oct 1
Bohemian Bungalow

10. Cozy 2-bedroom house in nice Port St. Lucie with AC

Cozy 2-bedroom house in nice Port St. Lucie with AC
Port St. Lucie
10.0 out of 10, Exceptional, (2 reviews)
"Communication was great! House was nice and clean apon arrival will be booking again"
United States
Shantalae J.
The price is ￥14,312
￥32,656 total
includes taxes & fees
Sep 24 - Sep 25
Cozy 2-bedroom house in nice Port St. Lucie with AC
A single-story house with a garage, a small front yard, and a tree.

11. Salt Coast Pool Side Retreat

Salt Coast Pool Side Retreat
Floresta Gardens
The price is ￥21,237
￥82,934 total
includes taxes & fees
Sep 24 - Sep 25
Salt Coast Pool Side Retreat
A room with a large window overlooking a wooden deck with a thatched roof, a pool, and outdoor seating.

12. Waterfront Tiki Oasis - Dock & Ocean Access

Waterfront Tiki Oasis - Dock & Ocean Access
River Park
10.0 out of 10, Exceptional, (1 review)
"Great place to stay. Clean and a perfect location. We will definitely stay here again. "
United States
Shaun B.
The price is ￥21,237
￥65,787 total
includes taxes & fees
Sep 29 - Sep 30
Waterfront Tiki Oasis - Dock & Ocean Access

13. Charming 2-bedroom guest house with Pool in Port St. Lucie

Charming 2-bedroom guest house with Pool in Port St. Lucie
Port St. Lucie
The price is ￥14,029
￥27,617 total
includes taxes & fees
Sep 24 - Sep 25
Charming 2-bedroom guest house with Pool in Port St. Lucie
A kitchen with a granite countertop, white cabinets, stainless steel appliances, and a trash can.

14. CHEERFUL 3 BEDROOM HOME

CHEERFUL 3 BEDROOM HOME
Port St. Lucie
8.4 out of 10, Very good, (16 reviews)
"The location was very convenient and they accept pets! "
United States
CATHERINE M.
The price is ￥15,745
￥47,550 total
includes taxes & fees
Oct 16 - Oct 17
CHEERFUL 3 BEDROOM HOME

15. Villa Blue - Private Heated Pool - Sleeps 8

Villa Blue - Private Heated Pool - Sleeps 8
Sandpiper Bay
10.0 out of 10, Exceptional, (23 reviews)
"Amazing place! So many fun things to do and was so beautiful on the inside!"
United States
Victoria K.
The price is ￥30,204
￥67,650 total
includes taxes & fees
Sep 27 - Sep 28
Villa Blue - Private Heated Pool - Sleeps 8
A modern living room with a sectional sofa, a glass coffee table, and a patterned rug.

16. Comfortable 3BR Home Base in a Prime Location

Comfortable 3BR Home Base in a Prime Location
Northport Village
The price is ￥23,618
￥62,647 total
includes taxes & fees
Sep 25 - Sep 26
Comfortable 3BR Home Base in a Prime Location
A bedroom with a bed, bedside table, dresser, and a ceiling fan.

17. Waterfront Canal Retreat w/ Private Entrance

Waterfront Canal Retreat w/ Private Entrance
Oak Hammock
Waterfront Canal Retreat w/ Private Entrance

18. Charming 3-bedroom house in lovely Port St. Lucie with AC

Charming 3-bedroom house in lovely Port St. Lucie with AC
Northport Village
The price is ￥31,175
￥79,695 total
includes taxes & fees
Sep 24 - Sep 25
Charming 3-bedroom house in lovely Port St. Lucie with AC
A covered patio with a table and chairs, a ceiling fan, and a view of the backyard.

19. The Glentry - Your Home Away From Home

The Glentry - Your Home Away From Home
Northport Village
The Glentry - Your Home Away From Home
A living room with two sofas, a flat-screen TV, and a ceiling fan.

20. Lovely 4-bedroom house in Port St Lucie

Lovely 4-bedroom house in Port St Lucie
Gatlin Pines
The price is ￥26,192
￥63,284 total
includes taxes & fees
Sep 24 - Sep 25
Lovely 4-bedroom house in Port St Lucie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Port Saint Lucie Hotel Reviews

SpringHill Suites Port St. Lucie

SpringHill Suites Port St. Lucie

10/10 Excellent
"On check in the front desk person was high and disoriented and kept nodding off. I told the manager the next day."
Annmarie 3-night trip
Posted less than an hour ago
SpringHill Suites Port St. Lucie

Find out more about Port Saint Lucie

Port Saint Lucie Vacation Homes information

Number of reviews
198
Accommodation
349 Vacation Homes
Lowest Price
￥26,535
Highest Price
￥80,381