Picayune Vacation Rentals

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Check prices for these dates

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Picayune vacation rentals

Terrace/patio
Adorable 3 bedroom attached cottage in quiet spot.

Vacation Home in Picayune

Adorable 3 bedroom attached cottage in quiet spot.
10.0 out of 10, Exceptional, (38)
"This property was very clean and quiet. Very cute little place to stay. I would 100% stay again."
United States
Melinda M.
The price is ￥14,736
￥24,562 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Adorable 3 bedroom attached cottage in quiet spot.
Interior
The Henry Smith House-Annex.

Vacation Home in Picayune

The Henry Smith House-Annex.
2.0 star property
9.6 out of 10, Exceptional, (7)
"Lovely home; great ameneties"
United States
veronica
The price is ￥42,104
￥69,579 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Henry Smith House-Annex.
Private kitchen
Charming 4-bedroom mobile home with WiFi, AC in Sun. Near tubing, river

Mobile Home in Bogalusa

Charming 4-bedroom mobile home with WiFi, AC in Sun. Near tubing, river
9.8 out of 10, Exceptional, (6)
"Absolutely loved this peaceful property"
United States
Brooke
The price is ￥14,053
￥25,706 total
includes taxes & fees
Dec 28 - Dec 29
Charming 4-bedroom mobile home with WiFi, AC in Sun. Near tubing, river
Private kitchen
Lovely class A motorhome

Mobile Home in Perkinston

Lovely class A motorhome
2.0 star property
10.0 out of 10, Exceptional, (2)
"Amazing view comfortable beds very spacious. "
United States
Anthony P.
The price is ￥39,035
￥47,782 total
includes taxes & fees
Dec 27 - Dec 28
Lovely class A motorhome
Cottage, Ensuite, Garden View (Salty Soul Cottage) | Interior
Carroll House Cottages

Cottage in Bay St Louis

Carroll House Cottages
3.0 star property
9.0 out of 10, Wonderful, (327)
"The host was very kind, the property was beautiful. "
United States
Stacey
The price is ￥14,346
￥31,784 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Carroll House Cottages
House (1 Bedroom) | Interior
Wraparound Deck: Unique Bay St Louis Home on Canal

Cottage in Bay St Louis

Wraparound Deck: Unique Bay St Louis Home on Canal
3.0 star property
10.0 out of 10, Exceptional, (1)
"Great stay!"
United States
Edward
The price is ￥15,282
￥44,861 total
includes taxes & fees
Dec 27 - Dec 28
Wraparound Deck: Unique Bay St Louis Home on Canal
House, 3 Bedrooms, Kitchen | Private kitchen
Drackett House by Whiskey Properties

Vacation Home in Old Town Bay St Louis

Drackett House by Whiskey Properties
2.0 star property
9.6 out of 10, Exceptional, (21)
"It was great place place to stay and we will be back."
United States
Pamela
The price is ￥11,636
￥14,396 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Drackett House by Whiskey Properties
Exterior
Cozy room .4 mile walk to beautiful seawall over looking the Bay of Saint Louis.

Apartment in Bay St. Louis

Cozy room .4 mile walk to beautiful seawall over looking the Bay of Saint Louis.
9.6 out of 10, Exceptional, (49)
"Perfect place to stay if you're going to a show at nearby Hollywood Casino or just enjoying Bay St. Louis. "
United States
Juliana
The price is ￥9,122
￥17,593 total
includes taxes & fees
Dec 28 - Dec 29
Cozy room .4 mile walk to beautiful seawall over looking the Bay of Saint Louis.
Exterior
Cozy 2-bedroom cottage near Bay Saint Louis Harbor

Cottage in Bay St. Louis

Cozy 2-bedroom cottage near Bay Saint Louis Harbor
10.0 out of 10, Exceptional, (120)
"Clean and quiet with comfortable beds."
United States
Carole O.
The price is ￥9,134
￥30,550 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Cozy 2-bedroom cottage near Bay Saint Louis Harbor
Fridge, microwave, oven, stovetop
Casa "Pura Vida"

Cottage in Bay Saint Louis

Casa "Pura Vida"
8.8 out of 10, Excellent, (13)
"House was clean."
United States
Vince D.
The price is ￥13,912
￥32,184 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Casa "Pura Vida"
Smart TV
BAY-CAY Getaway, Beaching, Casinos, Swim, Grill, Chill, Memories!

Cottage in Bay St. Louis

BAY-CAY Getaway, Beaching, Casinos, Swim, Grill, Chill, Memories!
10.0 out of 10, Exceptional, (53)
"This place was just wonderful!"
United States
Anna
The price is ￥17,956
￥36,421 total
includes taxes & fees
Jan 5 - Jan 6, 2026
BAY-CAY Getaway, Beaching, Casinos, Swim, Grill, Chill, Memories!
Fridge, microwave, stovetop, dishwasher
Cottage in Diamondhead

Vacation Home in Diamondhead

Cottage in Diamondhead
9.2 out of 10, Wonderful, (7)
"Place was great and owner was always very quick to respond "
United States
Susan
The price is ￥11,901
￥33,395 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Cottage in Diamondhead
Dining
3-bedroom home in the Mississippi Gulf Coast

Vacation Home in Pass Christian

3-bedroom home in the Mississippi Gulf Coast
8.6 out of 10, Excellent, (7)
"Get place to say "
United States
Willie W.
The price is ￥12,866
￥35,848 total
includes taxes & fees
Jan 4 - Jan 5, 2026
3-bedroom home in the Mississippi Gulf Coast
Fridge, microwave, oven, stovetop
Pet Friendly + Close to Casinos + Ample Parking

Vacation Home in Gulfport

Pet Friendly + Close to Casinos + Ample Parking
10.0 out of 10, Exceptional, (1)
"Nice place"
United States
Beth B.
The price is ￥13,935
￥54,050 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Pet Friendly + Close to Casinos + Ample Parking
Smart TV, books
Waterfront Beach & Lake House w/ BBQ, deck, & more

Vacation Home in Pass Christian

Waterfront Beach & Lake House w/ BBQ, deck, & more
9.6 out of 10, Exceptional, (14)
"Great pricing and great place!"
United States
S. John P.
The price is ￥10,624
￥43,288 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Waterfront Beach & Lake House w/ BBQ, deck, & more
Smart TV
Charming 1-bedroom apartment in Heart of Bogalusa, Sleeps 2

Apartment in Bogalusa

Charming 1-bedroom apartment in Heart of Bogalusa, Sleeps 2
9.8 out of 10, Exceptional, (8)
"Very clean very comfortable, very charming,,, in great location "
United States
Leslie
The price is ￥12,475
￥17,231 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Charming 1-bedroom apartment in Heart of Bogalusa, Sleeps 2
Beach nearby, sun loungers, beach towels
New cottage blocks from the beach; pets OK! Firepit! Grill! EV Charger! 65” TV

Cottage in Waveland

New cottage blocks from the beach; pets OK! Firepit! Grill! EV Charger! 65” TV
10.0 out of 10, Exceptional, (12)
"Excellent amenities and location. We had a great time and would stay again."
United States
Alex L.
The price is ￥18,869
￥45,214 total
includes taxes & fees
Jan 11 - Jan 12, 2026
New cottage blocks from the beach; pets OK! Firepit! Grill! EV Charger! 65” TV
Pool
Pool, Walk to Beach, Pet Friendly, Waffle Bar

Vacation Home in Pass Christian

Pool, Walk to Beach, Pet Friendly, Waffle Bar
10.0 out of 10, Exceptional, (6)
"Condo was perfect. Very clean! Close to the beach and close to restaurants and shops Would for sure stay here again! "
United States
Dana J.
The price is ￥19,522
￥54,889 total
includes taxes & fees
Dec 29 - Dec 30
Pool, Walk to Beach, Pet Friendly, Waffle Bar
Fridge, microwave, oven, stovetop
Quaint Cottage, Walk to Beach and Old Town Bay St. Louis

Cottage in Bay St Louis

Quaint Cottage, Walk to Beach and Old Town Bay St. Louis
9.8 out of 10, Exceptional, (83)
"Great location with a small fenced backyard for our K9 travel companions. Comfortable cottage has all you'll need to enjoy Bay St. Louis like a local."
United States
Rick B.
The price is ￥15,594
￥36,884 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Quaint Cottage, Walk to Beach and Old Town Bay St. Louis
Outdoor dining
Old Town Central Station - A home with charm!

Vacation Home in Bay St. Louis

Old Town Central Station - A home with charm!
2.0 star property
8.0 out of 10, Very Good, (12)
"Great location, ample parking, and wonderful communication. "
United States
Nicole Z.
The price is ￥10,821
￥32,048 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Old Town Central Station - A home with charm!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Picayune Hotel Reviews

Quality Inn Slidell I-10

Quality Inn Slidell I-10

10/10 Excellent
"Room is clean. Staff was very polite. "
Evelyn 1-night trip
Posted 3 days ago
Quality Inn Slidell I-10

Find out more about Picayune

Search for holiday rentals in Picayune on Expedia! You can easily find your home rentals, villas, holiday apartments in Picayune using one of the methods below:

  • View our selection of featured holiday rentals in Picayune
  • Use the map to find apartments and other holiday homes in the Picayune neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Picayune while they last

Look no further and take a look at our great range of rental properties in Picayune!

Frequently asked questions

Can I find vacation rentals in Picayune?

Yes, we have vacation rentals in Picayune near Crosby Arboretum, or you can choose a more remote option if you'd like a relaxing place to stay. Picayune is known for its coffeehouses and golf courses.

What are some of the best vacation rentals that Picayune has to offer?

Drackett House by Whiskey Properties: Visitors like this Picayune vacation home rental. It is located in the historical district and has a terrace, a barbecue grill, and free WiFi to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind.

How many vacation rentals are there in Picayune?

Choose from 13 Expedia vacation rentals in Picayune for a memorable vacation.

What can I see and do in Picayune?

Crosby Arboretum and McCarty Island are a couple of lovely local spots to get outside and enjoy nature. Other places in town to visit include Picayune City Hall and Millbrook Country Club.

What are vacation rentals like in Picayune?

Vacation rentals are private properties you can stay in for a short or long stay in Picayune. Vacation rentals feature extras such as hot tubs, fire pits, and patios so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for family trips.