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Our top choices for Perissa luxury hotels

Irigeneia Hotel

Irigeneia Hotel
4.0 star property
Santorini
9.4 out of 10, Exceptional, (137)
"Excellent location, very comfortable rooms, clean with nice view. Delicious breakfast and an excellent service, here you have the privilege to be attended by the owners, they a magnificent job."
United States
Wilson
The price is ¥10,300
¥12,251 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Irigeneia Hotel

Zen Suites & Spa

Zen Suites & Spa
5.0 star property
Santorini
The price is ¥40,088
¥46,263 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Zen Suites & Spa

Delion View Hotel

Delion View Hotel
4.0 star property
Santorini
9.4 out of 10, Exceptional, (228)
"The service is amazing"
United States
Diego
The price is ¥26,292
¥30,411 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Delion View Hotel

Ducato di Oia - Adults Only

Ducato di Oia - Adults Only
4.0 star property
Santorini
9.4 out of 10, Exceptional, (331)
"We enjoyed the stay. Thank you."
United States
Kazuiku
The price is ¥24,785
¥28,700 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Ducato di Oia - Adults Only

Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only
4.0 star property
Santorini
9.4 out of 10, Exceptional, (1000)
"Cleaning service provided daily, all hotel staff was very kind and professional. "
United States
EBONY
The price is ¥15,580
¥18,246 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Ira Hotel & Spa - Adults Only

Villa Manos

Villa Manos
4.0 star property
Santorini
8.8 out of 10, Excellent, (345)
"The place was very nice and clean and stuff there at the lobby and the restaurant are welcoming and helpful, food was amazing and price was reasonable."
United States
Amgad
The price is ¥7,161
¥8,685 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Villa Manos

De Sol Spa Hotel

De Sol Spa Hotel
5.0 star property
Santorini
9.4 out of 10, Exceptional, (525)
"The rooms were clean and the service outstanding. "
United States
Teresa
The price is ¥28,239
¥32,807 total
includes taxes & fees
Dec 29 - Dec 30
De Sol Spa Hotel

Suites of the Gods Cave Spa

Suites of the Gods Cave Spa
5.0 star property
Santorini
8.6 out of 10, Excellent, (293)
"From check-in to check-out, everything felt smooth and welcoming. We would happily stay here again and would recommend it to anyone looking for a comfortable and pleasant stay."
Canada
LADONNA
Suites of the Gods Cave Spa

Hotel Omiros

Hotel Omiros
4.0 star property
Santorini
8.2 out of 10, Very Good, (10)
"Good service Receptionist service was best Rooms are clean "
Canada
Dhanwinderjit S
Hotel Omiros

Rocabella Santorini Hotel & SPA

Rocabella Santorini Hotel & SPA
4.0 star property
Santorini
9.4 out of 10, Exceptional, (637)
"Excellent hotel location and friendly staff,good service. we love it. Hope we could come back.again in near future."
Canada
Fei
The price is ¥32,485
¥37,445 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Rocabella Santorini Hotel & SPA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Perissa Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Perissa vacation?
Travel to Santorini National Airport (JTR) Airport and then treat yourself to a stay at one of 5 Perissa luxury hotels. During your visit, you might want to enjoy the beaches which Perissa is known for.
What's the best high-end hotel in Perissa?
Antoperla Luxury Hotel & Spa is a luxury hotel with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Aqua Blue Hotel and Santo Mangata Boutique Hotel - Adults only are two other upscale options for your trip.
How many luxury hotels will I be able to find in Perissa?
Lie in the lap of luxury during your getaway to Perissa in one of Expedia's 5 luxury hotels.
When can I expect good weather in Perissa?
Planning for the weather is a good way to make your trip to Perissa relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 76°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Perissa is 13 inches.
What's there to see and do in Perissa?
Experience all that Perissa has to offer when you visit Perissa Beach, Ancient Thira, and Museum of Minerals and Fossils. If you have a little extra time during your trip, you might want to check out Kamari Beach and Perivolos Beach.