Lodging Image

Search Vacation Homes in Panhandle Plains

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Oct 23 - Oct 25
In two months
Dec 4 - Dec 6
In three months
Jan 1 - Jan 3
In four months
Jan 29 - Jan 31

Our top choices for Panhandle Plains vacation homes

A living room with a brown leather sofa, a coffee table, a wooden side table with a lamp, a patterned rug, and a mirror on the wall.

1. Comfy 2 bedroom home, near Palo Duro Canyon!

Comfy 2 bedroom home, near Palo Duro Canyon!
Canyon
9.4 out of 10, Exceptional, (86 reviews)
"Wonderful home, hosts were exceptional."
United States
Kimberly M.
The price is ￥16,590
￥24,095 total
includes taxes & fees
Nov 4 - Nov 5
Comfy 2 bedroom home, near Palo Duro Canyon!
A covered outdoor area with a wooden fence, a barbecue grill, and a bench.

2. Buffalo airport Fly Inn. 2 bedroom inside a airplane hangar!

Buffalo airport Fly Inn. 2 bedroom inside a airplane hangar!
Amarillo
10.0 out of 10, Exceptional, (57 reviews)
"Great time great place can tell it was a local airport."
United States
Cody
The price is ￥13,225
￥22,203 total
includes taxes & fees
Oct 20 - Oct 21
Buffalo airport Fly Inn. 2 bedroom inside a airplane hangar!
A bedroom with a four-poster bed, a ceiling fan, a bench, a desk with a lamp, and a window.

3. The Canyon Hideaway

The Canyon Hideaway
Canyon
10.0 out of 10, Exceptional, (79 reviews)
"Nice place to stay. "
United States
gayle m.
The price is ￥18,344
￥32,654 total
includes taxes & fees
Oct 14 - Oct 15
The Canyon Hideaway
A modern kitchen with wooden cabinets, a central island, stainless steel appliances, and a microwave.

4. Lincoln’s Landing spacious 3 BD 2 Bath near Palo Duro Canyon and WT

Lincoln’s Landing spacious 3 BD 2 Bath near Palo Duro Canyon and WT
Canyon
9.6 out of 10, Exceptional, (5 reviews)
"Comfortable clean quiet neighborhood. Convenient to things. Amazing musical at Palo Duro canyon. Great communication with Whitney."
United States
jean t.
The price is ￥16,424
￥38,266 total
includes taxes & fees
Oct 12 - Oct 13
Lincoln’s Landing spacious 3 BD 2 Bath near Palo Duro Canyon and WT
A modern kitchen with wooden cabinetry, a central island, and a dining area with stools.

5. Gorgeous Two Bedroom Modern Farmhouse Cottage

Gorgeous Two Bedroom Modern Farmhouse Cottage
Electra
10.0 out of 10, Exceptional, (61 reviews)
"We stayed for the Hotter than Hell ride in Wichita Falls. We were there for about 12 hours. But the place was nice overall."
United States
Andrew
The price is ￥18,802
￥28,952 total
includes taxes & fees
Oct 10 - Oct 11
Gorgeous Two Bedroom Modern Farmhouse Cottage
A modern kitchen with a built-in microwave, oven, and stainless steel refrigerator. There are two wicker chairs with cushions and a dark sofa with a throw blanket.

6. Rustic chic guesthouse located right next to HSU & Hendrick Medical Center

Rustic chic guesthouse located right next to HSU & Hendrick Medical Center
Sears Park Area
10.0 out of 10, Exceptional, (90 reviews)
"Great stay "
United States
Aubrey
The price is ￥19,750
￥37,604 total
includes taxes & fees
Oct 29 - Oct 30
Rustic chic guesthouse located right next to HSU & Hendrick Medical Center
A modern kitchen with white cabinets, a central island, pendant lighting, and stainless steel appliances.

7. Sunshine Casita! A quiet country setting. Short drive to Palo Duro Canyon.

Sunshine Casita! A quiet country setting. Short drive to Palo Duro Canyon.
Canyon
10.0 out of 10, Exceptional, (72 reviews)
"Our stay here was excellent! The property was very easy to find and check-in was very smooth. We only ran into two small issues while we were there, and the hosts were very quick to respond and solve them. We will definitely plan to stay here again when we are spending time in Canyon."
United States
Kelly
The price is ￥21,188
￥31,118 total
includes taxes & fees
Oct 14 - Oct 15
Sunshine Casita! A quiet country setting. Short drive to Palo Duro Canyon.
A kitchen with wooden cabinets, a stainless steel dishwasher, a gas stove, and a ceiling light fixture.

8. Welcoming 2-bedroom house with HVAC in Clarendon with large lot and court yard

Welcoming 2-bedroom house with HVAC in Clarendon with large lot and court yard
Clarendon
10.0 out of 10, Exceptional, (11 reviews)
"Clean, quiet, perfect for a quick stopover."
United States
Phillip
The price is ￥29,230
￥49,391 total
includes taxes & fees
Oct 11 - Oct 12
Welcoming 2-bedroom house with HVAC in Clarendon with large lot and court yard
A modern kitchen with wooden cabinets, a black countertop, and a stainless steel stove.

9. Griffin's Hangout 3 BR 2 Bath near Palo Duro Canyon and WT

Griffin's Hangout 3 BR 2 Bath near Palo Duro Canyon and WT
Canyon
10.0 out of 10, Exceptional, (14 reviews)
"Beautiful place Very clean "
United States
Kathy P.
The price is ￥17,206
￥40,750 total
includes taxes & fees
Oct 13 - Oct 14
Griffin's Hangout 3 BR 2 Bath near Palo Duro Canyon and WT
A kitchen with wooden cabinets, a central island with stools, a built-in oven, and a refrigerator.

10. Yellow Cottage Home Close to I-40 and I-27

Yellow Cottage Home Close to I-40 and I-27
Amarillo
10.0 out of 10, Exceptional, (105 reviews)
"The home was fantastic from the moment we arrived. Everything was exactly as described, clean, comfortable, and well-stocked. The space had a great layout and felt like a true home away from home. I highly recommend to anyone looking for a relaxing, hassle-free stay!"
United States
Estella H.
The price is ￥18,802
￥52,082 total
includes taxes & fees
Oct 17 - Oct 18
Yellow Cottage Home Close to I-40 and I-27
An outdoor area with a wooden floor, a covered seating area with red chairs, and a building entrance with windows and a door.

11. Blanche's Loft

Blanche's Loft
Graham
9.6 out of 10, Exceptional, (10 reviews)
"Great little place to stay! Very clean"
United States
Kayla
The price is ￥21,014
￥34,441 total
includes taxes & fees
Oct 11 - Oct 12
Blanche's Loft
A modern kitchen with white cabinetry, granite countertops, stainless steel appliances, and pendant lighting.

12. Beautifully Decorated New Home, King Bed, Washer/Dryer & Fully Stocked Kitchen

Beautifully Decorated New Home, King Bed, Washer/Dryer & Fully Stocked Kitchen
Canyon
10.0 out of 10, Exceptional, (53 reviews)
"Very clean and welcoming. Will stay again when we visit our daughter at college."
United States
Christopher P.
The price is ￥20,820
￥58,884 total
includes taxes & fees
Oct 14 - Oct 15
Beautifully Decorated New Home, King Bed, Washer/Dryer & Fully Stocked Kitchen
A compact kitchenette with a microwave, coffee maker, and a small refrigerator.

13. The Half Pint - Pet Friendly for 1 Pet Only

The Half Pint - Pet Friendly for 1 Pet Only
Abilene
9.4 out of 10, Exceptional, (23 reviews)
"Very convenient since it was close to the ABI airport and great price as well! I would definitely book again when down in Abilene!"
United States
Cynthia
The price is ￥9,111
￥16,175 total
includes taxes & fees
Oct 12 - Oct 13
The Half Pint - Pet Friendly for 1 Pet Only
A wooden cabinet with a glass door and a handle.

14. McKinley House - Garage, Gym and Fenced Back Yard

McKinley House - Garage, Gym and Fenced Back Yard
Amarillo
9.8 out of 10, Exceptional, (243 reviews)
"This place was amazing. Beautiful and good for more than a couple day visit. Would stay again"
United States
Felica R.
The price is ￥19,417
￥25,489 total
includes taxes & fees
Oct 12 - Oct 13
McKinley House - Garage, Gym and Fenced Back Yard
A concrete pathway leading to a wooden fence and a bench.

15. Horsefeathers 🐾 pet friendly funky comfort

Horsefeathers 🐾 pet friendly funky comfort
Amarillo
9.8 out of 10, Exceptional, (34 reviews)
"Everything was perfect."
United States
Tandy U.
The price is ￥23,542
￥40,992 total
includes taxes & fees
Oct 13 - Oct 14
Horsefeathers 🐾 pet friendly funky comfort
A dining area with a wooden floor, a table with chairs, and a chandelier. There is a staircase leading to another room.

16. Rustic retreat-near the Canyon

Rustic retreat-near the Canyon
Canyon
9.2 out of 10, Wonderful, (32 reviews)
"The home was beautiful and comfortable. It was perfect for our stay."
United States
Sherry G.
The price is ￥23,063
￥38,620 total
includes taxes & fees
Oct 13 - Oct 14
Rustic retreat-near the Canyon
A kitchen with white cabinets, a dishwasher, a refrigerator, and a microwave.

17. Emery’s Place GAME ROOM, 4BD 2BR near Palo Duro Canyon

Emery’s Place GAME ROOM, 4BD 2BR near Palo Duro Canyon
Canyon
9.2 out of 10, Wonderful, (12 reviews)
"Excellent property and exceeded my expectations. Would visit again!"
United States
Jason and Carrie H.
The price is ￥16,111
￥47,730 total
includes taxes & fees
Oct 15 - Oct 16
Emery’s Place GAME ROOM, 4BD 2BR near Palo Duro Canyon
A modern kitchen with dark wood cabinets, stainless steel appliances, and a granite countertop.

18. Cheerful 3-Bedroom Home w King Bed, Fireplace, W/D, 10 min from Palo Duro Canyon

Cheerful 3-Bedroom Home w King Bed, Fireplace, W/D, 10 min from Palo Duro Canyon
Canyon
10.0 out of 10, Exceptional, (76 reviews)
"Absolutely amazing home! The Host was extremely helpful and understanding as we had one accident during our stay. Highly recommend to anyone looking for a cozy and comfortable stay."
United States
Paul E.
The price is ￥19,799
￥57,286 total
includes taxes & fees
Oct 22 - Oct 23
Cheerful 3-Bedroom Home w King Bed, Fireplace, W/D, 10 min from Palo Duro Canyon
A spa area with a hot tub, a fireplace, and a seating area with chairs and a table.

19. Charming 2-bedroom house with indoor hot tub and spa! Free EV Charger!

Charming 2-bedroom house with indoor hot tub and spa! Free EV Charger!
Amarillo
9.4 out of 10, Exceptional, (23 reviews)
"We really loved the space of this home and will definitely book it again in the future."
United States
Andrea W.
The price is ￥26,876
￥43,111 total
includes taxes & fees
Oct 11 - Oct 12
Charming 2-bedroom house with indoor hot tub and spa! Free EV Charger!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Panhandle Plains Hotel Reviews

The Cactus Cove Inn and Suites

The Cactus Cove Inn and Suites

10/10 Excellent
"Kids loved it, had a live mermaid at the pool. I don’t think she was real but the kids like her. Great place for kids, lots to do, clean and good location. Pretty strong chlorine smell from the pool but other than that great stay."
Kristen 1-night trip
Posted 2 hours ago
The Cactus Cove Inn and Suites

Find out more about Panhandle Plains

Panhandle Plains Vacation Homes information

Number of reviews
921
Accommodation
939 Vacation Homes
Lowest Price
￥16,175
Highest Price
￥58,884

Explore a world of travel with Expedia