Default HTG hotel image

Panama Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Panama vacation rentals

1. State Street House; 3-br house; PETS WELCOME; Litchfield

State Street House; 3-br house; PETS WELCOME; Litchfield
Litchfield
9.4 out of 10, Exceptional, (15 reviews)
"Perfect location! Everything was great!"
United States
Kelly C.
The price is ¥25,273
¥40,260 total
includes taxes & fees
Aug 30 - Aug 31
State Street House; 3-br house; PETS WELCOME; Litchfield

2. Edwards House; Litchfield, IL; Pets welcome

Edwards House; Litchfield, IL; Pets welcome
Litchfield
10.0 out of 10, Exceptional, (27 reviews)
"Nice stay as our stopover point between Texas and Northern Wisconsin."
United States
Robert N.
The price is ¥18,915
¥29,649 total
includes taxes & fees
Aug 29 - Aug 30
Edwards House; Litchfield, IL; Pets welcome

3. Harrison House; Litchfield, IL; Pets welcome

Harrison House; Litchfield, IL; Pets welcome
Litchfield
10.0 out of 10, Exceptional, (21 reviews)
"Loved this property. Will def be staying again. "
United States
Amanda G.
The price is ¥18,454
¥30,170 total
includes taxes & fees
Sep 6 - Sep 7
Harrison House; Litchfield, IL; Pets welcome

4. Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!
Mulberry Grove
9.8 out of 10, Exceptional, (35 reviews)
"Went to visit kids who live in the area. Normally we get a hotel but decided to try doing something different. This was so much better than hotels and plan to go back next time we are down."
United States
Julie
The price is ¥15,855
¥31,291 total
includes taxes & fees
Sep 9 - Sep 10
Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews

Find out more about Panama

Search for holiday rentals in Panama on Expedia! You can easily find your home rentals, villas, holiday apartments in Panama using one of the methods below:

  • View our selection of featured holiday rentals in Panama
  • Use the map to find apartments and other holiday homes in the Panama neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Panama while they last

Look no further and take a look at our great range of rental properties in Panama!

Frequently asked questions

Are there vacation rentals in Panama?

Yes, there are vacation rentals close to popular points of interest in Panama, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals in Panama?

Private 7-Acre Family/Event Retreat | Pool, Theater, Game Room & Lake: This vacation home rental near Panama offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a balcony and a selection of games.

What can I see and do in Panama?

While you're exploring the area, Lake Lou Yeager and Walton Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Patriot's Park and Greenville Country Club.

What are vacation rentals like in Panama?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Panama. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for family trips or small group gatherings.