The Best Hotels Closest to Oklahoma Frontier Drugstore Museum in Guthrie for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Oklahoma Frontier Drugstore Museum hotels

A hotel with a covered entrance, a sign reading "La Quinta Inn & Suites," and a brick facade.

A hotel lobby with a red carpet, various seating options including armchairs and ottomans, a television mounted on the wall, and a large window with a view of a building.

A hotel room with a bed, nightstands, a sofa, a bathroom with a bathtub, and a wall-mounted picture.

A kitchenette with a West Bend microwave, a coffee maker, and a small refrigerator.

1. La Quinta Inn & Suites by Wyndham Guthrie

2.9 km from Oklahoma Frontier Drugstore Museum

Cyndi

￥14,090

￥16,346 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a wooden floor, a staircase, and a reception desk.

A hotel room with a large bed, two bedside tables, a chair, and a bathroom visible to the right.

A modern hotel lobby with a wooden desk, two sofas, a coffee table, and a staircase.

A covered outdoor seating area with a wooden pergola, a bench, and a small garden with rocks and plants.

2. Sleep Inn & Suites Guthrie - Edmond North

2.9 km from Oklahoma Frontier Drugstore Museum

Lisa

￥11,256

￥13,057 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a bed, a desk with a chair, a television, a mirror, and a microwave.

A reception desk with a wooden counter, a chandelier, framed pictures on the wall, and a potted plant.

A kitchen with wooden cabinets, a granite countertop, a coffee maker, and framed floral artwork on the wall.

A parking lot with a white truck parked on the right, a building with a green roof in the background, and a clear blue sky.

3. Interstate Motel Guthrie

2.4 km from Oklahoma Frontier Drugstore Museum

Mary

￥13,591

￥15,767 total

includes taxes & fees

Nov 10 - Nov 11

View all properties

Top Oklahoma Frontier Drugstore Museum Hotel Reviews

Stratford House Inns - Edmond

8/10 Good

"Staff was helpful at checking in Air conditioning worked perfectly for the warm weather."

Holiday Inn Express & Suites Oklahoma City North by IHG

10/10 Excellent

"Very clean hotel. Staff was very"

Comfort Inn & Suites Oklahoma City North - Quail Springs

10/10 Excellent

"Exceptional"

Hilton Garden Inn Edmond / Oklahoma City North, OK

8/10 Good

"We loved the bar tenders in evenings but the breakfast staff seemed short handed and overwhelmed . They were kind but we had to ask and wait for service every morning . Food was great."

La Quinta Inn & Suites by Wyndham Stillwater-University Area

10/10 Excellent

"Clean"

Country Inn & Suites by Radisson, Oklahoma City - Quail Springs, OK

10/10 Excellent

"Friendly quick check in room was great"

La Quinta Inn & Suites by Wyndham Edmond

8/10 Good

"Clean hotel"

Best Western Plus Memorial Inn & Suites

8/10 Good

"Very good place to stay. Front desk staff are very friendly."

Sleep Inn & Suites Edmond near University

10/10 Excellent

"Bed was super comfortable! Clean room, friendly and helpful staff. Great place to stay"

Other attractions near Oklahoma Frontier Drugstore Museum

Guthrie City Hall

Guthrie City Hall is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Discover the area's festivals and temples.

See properties

Guthrie Historic District

Learn about the local history of Guthrie when you spend time at Guthrie Historic District. Experience the area's festivals and live music.

See properties

Honor Park

Honor Park is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Experience the area's festivals and live music.

See properties

Pollard Theatre

8.0/10 (30 reviews)

Enjoy a performance at Pollard Theatre, a storied theater in Guthrie. Experience the area's festivals and live music.

See properties

Guthrie Public Library

Guthrie Public Library is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Experience the area's festivals and live music.

See properties

Guthrie Depot

You can learn about the history of Guthrie with a trip to Guthrie Depot. Experience the area's festivals and live music.

See properties

Jelsma Stadium

Catch an event at Jelsma Stadium during your trip to Guthrie. Discover the area's festivals and temples.

See properties

Oklahoma Territorial Museum and Carnegie Library

8.6/10 (51 reviews)

You can browse the exhibits at Oklahoma Territorial Museum and Carnegie Library, a museum with a storied past, during your travels to Guthrie. Experience the area's festivals and live music.

See properties

Frequently asked questions

What's the area like around Oklahoma Frontier Drugstore Museum?

Oklahoma Frontier Drugstore Museum is located in Guthrie. If you're looking for a convenient place to stay, check out the 32 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Oklahoma Frontier Drugstore Museum?

Hilton Garden Inn Edmond / Oklahoma City North, OK is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. You'll find it 13.5 mi (21.7 km) from Oklahoma Frontier Drugstore Museum. Other good options around the area include Executive Inn and La Quinta Inn & Suites by Wyndham Edmond.

How many hotels will I be able to find close to Oklahoma Frontier Drugstore Museum?

Expedia has 32 hotels and other accommodations within a mile from Oklahoma Frontier Drugstore Museum.

If I need to cancel the hotel reservation for my stay near Oklahoma Frontier Drugstore Museum, will I receive a refund?

Yes, most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get top deals close to Oklahoma Frontier Drugstore Museum.

Where can I learn more about changing or cancelling my trip in the area near Oklahoma Frontier Drugstore Museum?

For more details about updating your stay near Oklahoma Frontier Drugstore Museum or cancelling it, click here.

What can I see and do near Oklahoma Frontier Drugstore Museum?

You'll want to browse the exhibits at Scottish Rite Temple and Oklahoma Territorial Museum and Carnegie Library. Learn about local history at Guthrie Historic District and Guthrie Depot. If you have some time to wander around the area, you might stop by Jelsma Stadium, Guthrie Golf & Country Club, or Cimarron National Golf Club.

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Oklahoma Frontier Drugstore Museum hotels

1. La Quinta Inn & Suites by Wyndham Guthrie