A lush valley with dense green forests, rolling hills, and a cloudy sky.

Find hotels in Nuevo Santiago from ￥8,231

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Sep 8 - Sep 9
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Sep 9 - Sep 10
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Sep 11 - Sep 13
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Sep 18 - Sep 20

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Our top choices for Nuevo Santiago hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A restaurant with booths and tables, wooden paneling, and green plants.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
￥13,319
￥14,706 total
includes taxes & fees
Sep 9 - Sep 10
Hotel Mykonos Panama
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A hotel room with two single beds, a desk with a chair, a television, and a door.
A lobby with a reception desk, two armchairs, a sofa, and a table with a lamp.
A bathroom with a tiled shower wall, a sink, and a towel rack.

2. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
￥7,432
￥8,231 total
includes taxes & fees
Oct 9 - Oct 10
Hotel Plaza Los Tucanes
A pool surrounded by palm trees and a tiled roof structure.
A building with a curved facade, a balcony with metal railings, and a door with a sign.
A spacious room with a high ceiling, a large window, and a wooden door leading to another area. There are several potted plants and a small table with a vase.
A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.

3. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
￥10,196
￥11,316 total
includes taxes & fees
Sep 9 - Sep 10
Hotel Gran David
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A multi-story hotel with balconies, a pool, and a reflection in the water.
A hammock suspended between two white walls in a room with a balcony.

4. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Hedwig
￥11,321
￥12,500 total
includes taxes & fees
Sep 19 - Sep 20
HOTEL VISTA LAGO
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Learn more about Nuevo Santiago

Check out Parque Acuatico Italia Guadalupe Panama and Los Pozos Termales—just a couple of the sights around Nuevo Santiago.

See all hotels in Nuevo Santiago
A lush valley with dense green forests, rolling hills, and a cloudy sky.

Top Nuevo Santiago Hotel Reviews

Hotel Gran David

Hotel Gran David

10/10 Excellent
"I love this hotel. Always stay here when visiting Santiago from the states. I definitely fell safe here"
Jessica 1-night trip
Posted 21 hours ago
Hotel Gran David
HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Balcony"
Carmen 1-night trip
Posted 3 days ago
HOTEL VISTA LAGO
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 2 weeks ago
Hotel Plaza Los Tucanes

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Frequently asked questions

Where is the best place for a stay in Nuevo Santiago?
Hotel Mykonos Panama is one of the top choices for your stay based on our traveler data. This hotel offers 3 outdoor pools and a full-service spa. Other good choices for your stay include Hotel Plaza Los Tucanes and Hotel Galería. See all available top hotels, or vacation rentals in Nuevo Santiago.
What's the top vacation rental that Nuevo Santiago has to offer?
Perfect 1-bedroom bungalow with AC in peaceful Playa reina: This vacation home rental near Nuevo Santiago comes with air-conditioning so you can feel at home during your trip. See all vacation rentals in Nuevo Santiago.
If I need to cancel my hotel reservation in Nuevo Santiago, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Nuevo Santiago.
Where can I learn more about changing or cancelling my trip to Nuevo Santiago?
To access more information about changing or cancelling your trip to Nuevo Santiago, go to https://www.expedia.com/service/.
How is it staying in Nuevo Santiago?
Travelers to Nuevo Santiago will find plenty to explore and enjoy. In Nuevo Santiago, there are 4 hotels and other accommodations to choose from. Find out more about Nuevo Santiago.
What should I see while I'm in Nuevo Santiago?
Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Los Pozos Termales, and Plaza Banconal. You'll also find Omar Torrijos Herrera Stadium and Escuela Normal Juan Demostenes Arosemena in the area. Check out what more to see and do in Expedia's Nuevo Santiago guide.
What's the weather like in Nuevo Santiago?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Nuevo Santiago are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.

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